Abstract: A coaxial loudspeaker apparatus (10) comprising a first unit (20) being arranged to propagate sound in a first frequency range; a second unit comprising a first waveguide (30) arranged to propagate sound in a second frequency range that is higher than the first frequency range, and a second waveguide (60) arranged to move, during operation, relative to the first waveguide (30); wherein the second waveguide (60) extends substantially in prolongation of the first waveguide (30). The invention also extends to a loudspeaker (190) incorporating the coaxial loudspeaker apparatus (10).

Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A, L, and B are as defined herein, and methods of making and using the same.

Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.

Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (Ia): including stereoisomers and pharmaceutically acceptable salts thereof, wherein A?, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: The disclosure provides TNF-like ligand 1a (TL1a)-binding proteins comprising an antigen binding domain of an antibody which binds specifically to TL1a and inhibits interaction of TL1a and Death Receptor 3 (DR3) and which does not inhibit the interaction of TL1a and Decoy Receptor 3 (DcR3). The disclosure also provides uses of the TL1a-binding proteins.

Abstract: In some embodiments an apparatus includes a processor included within a compute device, operatively coupled to a memory, and is configured to execute an application module and a recording module. The application module is configured to receive, at a compute device, an indication of a user selection of a video request from a list of video requests. The video request is associated with a list of characteristics and is associated with a video request identifier. The application module is configured to, based on the video request identifier, define a video recording environment in accordance with the list of characteristics. The recording module is configured to record, during a time and using a camera integrated with the compute device, a video such in accordance with the list of characteristics. The application module is configured to associate the video with a relationship indicator indicative of the relationship between the video and the video request.

Abstract: Provided herein is an antibody comprising an antigen binding domain which binds to human IL-12 and human IL-23. The antibody binds human IL-12p40 existing as a monomer (human IL-12p40) and as a homodimer (human IL-12p80), and the antibody inhibits the binding of human IL-12 to human IL-12R?2 and human IL-23 to human IL-23R but does not inhibit the binding of human IL-12 or human IL-23 or human IL-12p40 or human IL-12p80 to human IL-12R?1.

Abstract: Inter-profile commissioning method and apparatus for a network The invention relates to a commissioning apparatus (130, 140) and method for configuring a joining node (150) of a first profile for operation in a network in accordance with a second profile, wherein the commissioning apparatus (130, 140) is arranged to emulate a commissioning process corresponding to the first profile.

Abstract: The invention relates to a system and method for monitoring a handshaking exchange between a call initiator and a call recipient to determine if handshaking has failed, to avoid repeated failed calls between the call initiator and the call recipient.

Abstract: In some embodiments an apparatus includes a processor included within a compute device, operatively coupled to a memory, and is configured to execute an application module and a recording module. The application module is configured to receive, at a compute device, an indication of a user selection of a video request from a list of video requests. The video request is associated with a list of characteristics and is associated with a video request identifier. The application module is configured to, based on the video request identifier, define a video recording environment in accordance with the list of characteristics. The recording module is configured to record, during a time and using a camera integrated with the compute device, a video such in accordance with the list of characteristics. The application module is configured to associate the video with a relationship indicator indicative of the relationship between the video and the video request.

Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (Ia): including stereoisomers and pharmaceutically acceptable salts thereof, wherein A?, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: The invention enables digital music content to be downloaded to and used on a portable wireless computing device. An application running on the wireless device has been automatically adapted to parameters associated with the wireless device without end-user input (e.g. the application has been configured in dependence on the device OS and firmware, related bugs, screen size, pixel number, security models, connection handling, memory etc. This application enables an end-user to browse and search music content on a remote server using a wireless network; to download music content from that remote server using the wireless network and to playback and manage that downloaded music content. The application also includes a digital rights management system that enables unlimited legal downloads of different music tracks to the device and also enables any of those tracks stored on the device to be played so long as a subscription service has not terminated.

Abstract: The present invention relates to an apparatus, method and computer program product for controlling reception in an asynchronous operation mode, wherein a transmitter sends an extended preamble sequence of length longer than the maximum length of a wake up message itself plus the maximum length of a gap between wake up messages, such that a receiver turning on during a sequence of wake up commands and not detecting the wake up commands, can be sure to successfully detect a preamble if it tries again a second time a set interval later.

Abstract: The invention relates a wireless node and to a method for operating the wireless node, wherein the wireless node comprises a controller arranged for communicating wirelessly with at least one further wireless node so as to determine an ability of the wireless node and to create a network, wherein a characteristic of the network depends on the ability of the wireless node.

Abstract: A control system including: a base including a central axis; a knob rotatably connected to the base, the knob rotatable about the central axis; a plurality of individually indexed light emitting elements distributed along the base perimeter and arranged to direct light radially outward of the central axis; a diffuser arranged radially outward of the light emitting elements; a wireless communication module enclosed between the knob and base; and a processor enclosed between the knob and base, the processor connected to the wireless communication mechanism and plurality of light emitting elements, the processor configured to individually control each light emitting element based on a control signal received from the wireless communication mechanism.

Abstract: Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.