Patents by Inventor Philip Arden Beachy

Philip Arden Beachy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for hedgehog pathway blockade in proliferative disorders, including hematopoietic malignancies
    Patent number: 7867492
    Abstract: Elevated Hedgehog (Hh) pathway activity, including ligand stimulated Hh pathway activity, was detected in hematopoietic malignancy cells, and determined to be associated with growth and proliferation of the malignancy cells. Accordingly, methods are provided for treating a hematopoietic cell malignancy associated with elevated Hh pathway activity by reducing or inhibiting the Hh pathway activity. Also provided are methods of determining the responsiveness of a hematopoietic cell malignancy to treatment with an Hh pathway antagonist.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: January 11, 2011
    Assignees: The John Hopkins University, The Board Trustees of the Leland Stanford Junior University
    Inventors: Philip Arden Beachy, Jynho Kim
  • COMPOUNDS FOR HEDGEHOG PATHWAY BLOCKADE IN PROLIFERATIVE DISORDERS, INCLUDING HEMATOPOIETIC MALIGNANCIES
    Publication number: 20090130091
    Abstract: Elevated Hedgehog (Hh) pathway activity, including ligand stimulated Hh pathway activity, was detected in hematopoietic malignancy cells, and determined to be associated with growth and proliferation of the malignancy cells. Accordingly, methods are provided for treating a hematopoietic cell malignancy associated with elevated Hh pathway activity by reducing or inhibiting the Hh pathway activity. Also provided are methods of determining the responsiveness of a hematopoietic cell malignancy to treatment with an Hh pathway antagonist.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 21, 2009
    Applicants: The Johns Hopkins University, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Philip Arden Beachy, Jynho Kim