Patents by Inventor Philip Blatcher

Philip Blatcher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purine derivative
    Patent number: 7737126
    Abstract: A compound of formula (I) and salts and solvates thereof are disclosed. Compounds of formula (I) are agonists of the adenosine A2A receptor and are believed to be of potential use in the treatment of inflammatory diseases such as asthma and chronic obstructive pulmonary disease.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: June 15, 2010
    Assignee: Glaxo Group Limited
    Inventors: Philip Blatcher, Richard Peter Charles Cousins, Derek Norman Evans
  • Novel Process and Formulations
    Publication number: 20080268044
    Abstract: The present invention provides for a novel process of making 6-carboxylic acid derivatives of pyrido[2,3-d]pyrimidin-7-one's, as well as a novel process for making 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]-amino}pyrido[2,3-d]pyrimidin-7(8H)-one, and salts thereof.
    Type: Application
    Filed: November 15, 2006
    Publication date: October 30, 2008
    Inventors: John Robert George Appleby, Philip Blatcher, Ann M. Diederich, Lesley Anne Humphries, Jiri Kasparec, As'ad Abu Khalil, Richard S. Lloyd, Paul G. Spoors, John J. Taggart, Lois E. Vernon
  • Purine Derivative
    Publication number: 20080132526
    Abstract: The present invention provides a compound of formula (I) and salts and solvates thereof. Compounds of formula (I) are agonists of the adenosine A2A receptor and are believed to be of potential use in the treatment of inflammatory diseases such as asthma and chronic obstructive pulmonary disease.
    Type: Application
    Filed: May 23, 2005
    Publication date: June 5, 2008
    Applicant: GLAXO GROUP LIMITED
    Inventors: Philip Blatcher, Richard Peter Charles Cousins, Derek Norman Evans
  • Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulphonamide
    Patent number: 5786473
    Abstract: A process for the preparation of the compound of formula (I) ##STR1## or a salt thereof which comprises reducing the compound of formula (II) ##STR2## or a salt thereof. The novel intermediate of formula (II) and processes for preparing it are also described.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: July 28, 1998
    Assignee: Glaxo Group Limited
    Inventors: Philip Blatcher, Malcolm Carter, Roy Hornby, Martin Richard Owen
  • Process for the preparation of N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulphonamide
    Patent number: 5659040
    Abstract: A process for the preparation of the compound of formula (I) ##STR1## or a salt thereof which comprises reducing the compound of formula (II) ##STR2## or a salt thereof. The novel intermediate of formula (II) and processes for preparing it are also described.
    Type: Grant
    Filed: February 29, 1996
    Date of Patent: August 19, 1997
    Assignee: Glaxo Group Limited
    Inventors: Philip Blatcher, Malcolm Carter, Roy Hornby, Martin Richard Owen
  • Heterocyclic derivatives
    Patent number: 4585781
    Abstract: This invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts and hydrates thereof, in which R.sub.1 represents a hydrogen atom or an alkyl, alkanoyl, aroyl or trifluoroalkyl group;R.sub.2 represents a hydrogen atom or an alkyl or alkenyl group or C.sub.2-6 alkyl group substituted by a hydroxy or alkoxy group;X represents a sulphur atom or NH;Y represents an oxygen or sulphur atom or a bond;m represents 1, 2 or 3; andn represents 2, 3 or 4.The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.
    Type: Grant
    Filed: December 30, 1983
    Date of Patent: April 29, 1986
    Assignee: Glaxo Group Limited
    Inventors: David Bays, Roger Hayes, Philip Blatcher
  • 1,2,4-Triazole-3-amines, their pharmaceutical compositions and method of use
    Patent number: 4518598
    Abstract: The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts, and hydrates thereof. The substituents are defined in the specification.The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.
    Type: Grant
    Filed: January 9, 1984
    Date of Patent: May 21, 1985
    Assignee: Glaxo Group Limited
    Inventors: Roger Hayes, David E. Bays, John W. M. Mackinnon, Linda Carey, Philip Blatcher
  • 1,2,4-Triazole-3-amine and 1,2,4 triazole-3,5-diamine compounds and their pharmaceutical use
    Patent number: 4481199
    Abstract: The invention provides compounds of the general formula (I) ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which the substituents are defined later.The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.
    Type: Grant
    Filed: July 6, 1983
    Date of Patent: November 6, 1984
    Assignee: Glaxo Group Limited
    Inventors: Linda Carey, Barry J. Price, John W. Clitherow, John Bradshaw, Michael Martin-Smith, David E. Bays, Philip Blatcher