Patents by Inventor Philip Chun-Ying Wong

Philip Chun-Ying Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mouse expressing non-native wild-type and familial Alzheimer's Disease mutant presenilin 1 protein on native presenilin 1 null background
    Patent number: 6452065
    Abstract: The present invention relates to a transgenic non-human animal embryo lacking native presenilin 1 and a transgenic non-human animal having only a non-native presenilin 1. The transgenic animals and cells derived therefrom can be used in the study of the expression pattern, activity and modulators of presenilin 1, in the study of the role of presenilin 1 in Alzheimer's Disease and in the study of disorders of the central nervous system.
    Type: Grant
    Filed: May 14, 1998
    Date of Patent: September 17, 2002
    Assignees: Merck & Co., Inc., Johns Hopkins University
    Inventors: Hui Zheng, Ping Jiang, Su Qian, Leonardus H. T. Van Der Ploeg, Philip Chun-Ying Wong, Sangram S. Sisodia
  • TRANSGENIC ANIMAL EXPRESSING NON-NATIVE WILD-TYPE AND FAMILIAL ALZHEIMER'S DISEASE MUTANT PRESENILIN 1 PROTEIN ON NATIVE PRESENILIN 1 NULL BACKGROUND
    Publication number: 20020016978
    Abstract: The present invention relates to a transgenic non-human animal embryo lacking native presenilin 1 and a transgenic non-human animal having only a non-native presenilin 1. The transgenic animals and cells derived therefrom can be used in the study of the expression pattern, activity and modulators of presenilin 1, in the study of the role of presenilin 1 in Alzheimer's Disease and in the study of disorders of the central nervous system.
    Type: Application
    Filed: May 14, 1998
    Publication date: February 7, 2002
    Inventors: HUI ZHENG, PING JIANG, SU QIAN, LEONARDUS H. T. VAN DER PLOEG, PHILIP CHUN-YING WONG, SANGRAM S. SISODIA