Abstract: Methods and apparatus, including computer program products, are provided for remote monitoring. In some example implementations, there is provided a method. The method may include receiving, at a remote monitor, a notification message representative of an event detected, by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, wherein the remote monitor is configured by the server to receive the notification message to augment the receiver monitoring of the analyte state of the host; accessing, by the remote monitor, the server, in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.

Abstract: An aspect of the present disclosure is directed to and provides radar-reflecting systems and apparatus that employ metasurfaces to produce enhanced radar cross sections that are greater than those produced by the geometry of the surfaces alone. Another aspect of the present disclosure is directed to and provides heat-ducting systems and apparatus that include metasurfaces. A further aspect of the present disclosure is directed to and provides cards with metasurfaces. Exemplary embodiments utilize fractal plasmonic surfaces for a metasurface.

Abstract: Techniques are disclosed for handling database queries from multiple different application versions using a single database. A computer system executing a database management system (DBMS) may receive a database query for a database, where the database query is received from a particular version of an application having a plurality of versions. The database query may specify the particular version. The computer system may then identify catalog tables, where the catalog tables include version information columns storing version access information. The computer system may determine that version access information for the database query indicates that one or more database objects corresponding to the database query are accessible to the particular version of the application.

Abstract: The present invention is directed to a method of making at least a portion of a garment that includes at least one three-dimensional contour. The disclosed method includes providing a fiber and solvent mixture that includes fibers and a solvent capable to causing a plurality of covalent bonds to be created between the fibers. In many embodiments, the plurality of covalent bonds form when a catalyst, such as heat, is provided to the fiber and solvent mixture. The process can be performed using, for example, either a 3D printer or mold form. The fibers used can be natural, synthetic, or a blend of natural and/or synthetic fibers. The solvent preferably includes ionic salts in water.

Abstract: An electronic wagering system may include a wager selection station, a server, and a software application executed by a mobile communication device. At least one processor of the wager selection station may accept user input specifying parameters of an event on which to place a wager, generate a unique reference from which the specified event parameters are derivable, encode the unique reference in a machine-readable optical code, and display the generated optical code. The software application may operate the user's mobile communication device to scan the displayed optical code, retrieve the unique reference by decoding the scanned optical code, transmit the unique reference to the server for deriving the specified event parameters from the unique reference at the server, receive user input to place a wager on the event with the specified parameters, and transmit a request to the server to place the wager on behalf of the user.

Abstract: The disclosure relates to transferred learning from a first language (e.g., a source language for which a semantic parser has been defined) to a second language (e.g., a target language for which a semantic parser has not been defined). A system may use knowledge from a trained model in one language to model another language. For example, the system may transfer knowledge of a semantic parser from a first (e.g., source) language to a second (e.g., target) language. Such transfer of knowledge may occur and be useful when the first language has sufficient training data but the second language has insufficient training data. The foregoing transfer of knowledge may extend the semantic parser for multiple languages (e.g., the first language and the second language).

Abstract: The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.

Abstract: The disclosure relates to transferred learning from a first language (e.g., a source language for which a semantic parser has been defined) to a second language (e.g., a target language for which a semantic parser has not been defined). A system may use knowledge from a trained model in one language to model another language. For example, the system may transfer knowledge of a semantic parser from a first (e.g., source) language to a second (e.g., target) language. Such transfer of knowledge may occur and be useful when the first language has sufficient training data but the second language has insufficient training data. The foregoing transfer of knowledge may extend the semantic parser for multiple languages (e.g., the first language and the second language).

Abstract: The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.

Abstract: The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.

Abstract: An electronic wagering system may include a wager selection station, a server, and a software application executed by a mobile communication device. At least one processor of the wager selection station may accept user input specifying parameters of an event on which to place a wager, generate a unique reference from which the specified event parameters are derivable, encode the unique reference in a machine-readable optical code, and display the generated optical code. The software application may operate the user's mobile communication device to scan the displayed optical code, retrieve the unique reference by decoding the scanned optical code, transmit the unique reference to the server for deriving the specified event parameters from the unique reference at the server, receive user input to place a wager on the event with the specified parameters, and transmit a request to the server to place the wager on behalf of the user.

Abstract: The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.

Abstract: The present invention relates to compounds of formula I: or pharmaceutically acceptable acid addition salts thereof, where; R1 is C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C3 alkyl, substituted C3-C7 cycloalkyl-C1-C3 alkyl, phenyl, substituted phenyl, heterocycle, or substituted heterocycle; R2 is hydrogen, C1-C3 alkyl, C3-C6 cycloalkyl-C1-C3 alkyl, or a group of formula II R3 is hydrogen or C1-C3 alkyl; R4 is hydrogen, halo, or C1-C3 alkyl; R5 is hydrogen or C1-C3 alkyl; R6 is hydrogen or C1-C6 alkyl; and n is an integer from 1 to 6 inclusively. The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds of Formula I.

Abstract: The present invention relates to compounds of formula I: or pharmaceutically acceptable acid addition salts thereof, where; R1 is C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C3 alkyl, substituted C3-C7 cycloalkyl-C1-C3 alkyl, phenyl, substituted phenyl, heterocycle, or substituted heterocycle; R2 is hydrogen, C1-C3 alkyl, C3-C6 cycloalkyl-C1-C3 alkyl, or a group of formula II R3 is hydrogen or C1-C3 alkyl; R4 is hydrogen, halo, or C1-C3 alkyl; R5 is hydrogen or C1-C3 alkyl; R6 is hydrogen or C1-C6 alkyl; and n is an integer from 1 to 6 inclusively. The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds of Formula I.

Abstract: The invention relates to kinase inhibitors of the formula (I) in which —R1 to R4?H; ether or polyether, amino; NO2; NH-carbamate; NH—CO—R, with R such as defined above; N3 and derivatives thereof of the 1,2,3-triazole type; —R5=—OH; halogen; —OR with R such as defined above; OH-carbamate; OH-carbonate; NH2, NH-carbamate; NH—CO—R, with R such as defined above; N3 and derivatives thereof of the 1,2,3-triazole type; N(R9,R10); —R5??H or a C1-C12 alkyl, —R6?H; R; (R or R?)3—Si, with R such as defined above; optionally substituted aryl, heteroaryl; halogen (iodine); alkynyl; —R7 and R8?H, C1-C12 alkyl; —R9 and R10?H, R (or R?) such as defined above. These compounds can be used as kinase inhibitors in particular for treating cancer.

Abstract: The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.

Abstract: The present invention relates to compounds of formula I: or pharmaceutically acceptable acid addition salts thereof, where; R1 is C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C3 alkyl, substituted C3-C7 cycloalkyl-C1-C3 alkyl, phenyl, substituted phenyl, heterocycle, or substituted heterocycle; R2 is hydrogen, C1-C3 alkyl, C3-C6 cycloalkyl-C1-C3 alkyl, or a group of formula II R3 is hydrogen or C1-C3 alkyl; R4 is hydrogen, halo, or C1-C3 alkyl; R5 is hydrogen or C1-C3 alkyl; R6 is hydrogen or C1-C6 alkyl; and n is an integer from 1 to 6 inclusively. The compounds of the present invention are useful for activating 5-HTlF receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds of Formula I.

Abstract: The invention relates to pyrrolo[2,3-a]carbazole derivatives, to a method for preparing the same, and to the use thereof as PIM kinase inhibitors. The invention can particularly be used in the pharmaceutical field.

Abstract: The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently —C(H)? or —N?, provided that at least one of A and B is —N?, n is 1-3, m is 0-3, and R1-4 are as defined herein.

Abstract: An adjustable gastric band (AGB) positionable around a human stomach to limit the flow of food therethrough is provided with an improved structure for receiving and retaining suture from the stomach to the gastric restrictive device and thereby enabling a safer gastro-gastric plication while simultaneously preventing movement of the gastric fundus relative to the gastric restrictive device while additionally reducing the risk of tissue in-growth around and through the fenestrations, apertures or interstices of prior adjustable gastric band (AGB) structures for receiving and retaining sutures, which will render this embodiment safer in regard to the need for any potential revision procedures which may require relocating, removing or replacing the adjustable gastric bands in the future as well as enabling a safer gastro-gastricbuttress plication which will reduce the incidence of both “slippage” and “erosion.