Patents by Inventor Philip Coish

Philip Coish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for reducing enones to saturated alcohols or ketones
    Patent number: 11760708
    Abstract: The invention relates to novel, scalable synthetic routes that allow for direct reduction of enones to the corresponding saturated alcohols. The invention relates, in certain aspects, to synthetic routes that allow for the reduction of enones to the corresponding ketones. Such reactions take place under mild conditions, are compatible with a wide range of functional groups, and expand the repertoire of existing green chemistry methodology. In certain embodiments, the reactions are run in aqueous solvent.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: September 19, 2023
    Assignee: YALE UNIVERSITY
    Inventors: Laurene Petitjean, Paul Thomas Anastas, Tamara Marie DeWinter, Philip Coish, Hanno Christian Erythropel, Predrag Petrovic
  • Compositions and Methods for Reducing Enones to Saturated Alcohols
    Publication number: 20210163384
    Abstract: The invention relates to novel, scalable synthetic routes that allow for direct reduction of enones to the corresponding saturated alcohols. The invention relates, in certain aspects, to synthetic routes that allow for the reduction of enones to the corresponding ketones. Such reactions take place under mild conditions, are compatible with a wide range of functional groups, and expand the repertoire of existing green chemistry methodology. In certain embodiments, the reactions are run in aqueous solvent.
    Type: Application
    Filed: December 2, 2020
    Publication date: June 3, 2021
    Inventors: Laurene Petitjean, Paul Thomas Anastas, Tamara Marie DeWinter, Philip Coish, Hanno Christian Erythropel, Predrag Petrovic
  • Pyrimidinothienoindazoles useful for the treatment of hyperproliferative disorders
    Patent number: 8207172
    Abstract: The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: June 26, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Chengzhi Zhang, Jacques Dumas, Qingming Zhu, Roger Smith, Qingjie Liu, Sharad Verma, Jason Duquette, Qian Zhao, Dongping Fan, Georgiy Bondar, Philip Coish
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 8013166
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: September 6, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Roger A. Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen J. O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • NOVEL HETEROCYCLES
    Publication number: 20110172224
    Abstract: The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
    Type: Application
    Filed: August 19, 2005
    Publication date: July 14, 2011
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Chengzhi Zhang, Jacques Dumas, Qingming Zhu, Roger Smith, Qingjie Liu, Sharad Verma, Jason Duquette, Qian Zhao, Dongping Fan, Georgiy Bondar, Philip Coish
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7968576
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: June 28, 2011
    Inventors: Roger A. Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen J. O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20110118302
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: July 14, 2010
    Publication date: May 19, 2011
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen J. O'Connor, Philip Coish, Derek Lowe, Roger B. Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20100234307
    Abstract: This invention relates to certain biphenyl amino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: May 6, 2010
    Publication date: September 16, 2010
    Applicant: Bayer HealthCare LLC
    Inventors: Roger A. Smith, Derek Lowe, Tatiana Shelekhin, Georgiy Bondar, Philip Coish, Stephen J. O'Connor
  • Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity
    Patent number: 7759376
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: July 20, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Roger Smith, Stephen J. O'Connor, Philip Coish, Derek Lowe, Roger B. Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity
    Publication number: 20100016295
    Abstract: This invention relates to certain biphenyl amino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: July 31, 2006
    Publication date: January 21, 2010
    Applicant: Bayer Healthcare LLC
    Inventors: Roger A. Smith, Derek Lowe, Tatiana Shelekhin, Georgiy Bondar, Philip Coish, Stephen J. O'Connor
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Publication number: 20090270468
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: September 5, 2008
    Publication date: October 29, 2009
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Minghao Zhang, Lei Zhu
  • PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20090253762
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: September 8, 2008
    Publication date: October 8, 2009
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity
    Publication number: 20090215780
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: April 18, 2006
    Publication date: August 27, 2009
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Derek Lowe, Philip Coish, Ann-Marie Campbell, Gan Wang, Manoj Patel, Gerogiy Bondar
  • PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20090197795
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: August 4, 2008
    Publication date: August 6, 2009
    Applicant: Bayer HealthCare LLC
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Selective neuropeptide y2 receptor agonists
    Publication number: 20090105122
    Abstract: This invention provides peptides that act as selective NPY2 receptor agonists in vitro and are efficacious in vivo to reduce food intake. The invention is a peptide selected from a specific group of derivatized NPY-related peptides, or functional equivalents thereof. The invention is also directed to a method of treating a metabolic disease in a mammal comprising administering a therapeutically effective amount of the peptides to said mammal to reduce food intake and body weight.
    Type: Application
    Filed: November 23, 2004
    Publication date: April 23, 2009
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Kevin Lumb, Lynn Decarr, Philip Coish, Stephen O'Connor
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7423156
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: September 9, 2008
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity
    Publication number: 20070265298
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: October 14, 2005
    Publication date: November 15, 2007
    Applicant: Bayer Pharmaceuticals corporation
    Inventors: Roger Smith, Stephen O'Connor, Philip Coish, Derek Lowe, Roger Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
    Publication number: 20060205723
    Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
    Type: Application
    Filed: May 5, 2006
    Publication date: September 14, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Derek Lowe, Philip Wickens, Xin Ma, Mingbao Zhang, William Bullock, Philip Coish, Ingo Mugge, Andreas Stolle, Ming Wang, Yamin Wang, Chengzhi Zhang, Hai-Jun Zhang, Lei Zhu, Manami Tsutsumi, James Livingston
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Publication number: 20060194859
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: January 27, 2006
    Publication date: August 31, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7091228
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: August 15, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu