Patents by Inventor Philip D. Drew

Philip D. Drew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligands That Bind Il-4 and/or Il-13
    Publication number: 20110159003
    Abstract: Disclosed are ligands that have binding specificity for interleukin-4 (IL-4), for interleukin-13 (IL-13), or for IL-4 and IL-13. Also disclosed are methods of using these ligands. In particular, the use of these ligands for treating allergic asthma is described.
    Type: Application
    Filed: January 24, 2007
    Publication date: June 30, 2011
    Applicant: Domantis Limited
    Inventors: Ian Tomlinson, Allart Adriaan Stoop, Armin Sepp, Inusha De Silva, Caroline J. Dimech, Malgorzata Pupecka, Rudolf M.T. De Wildt, Philip D. Drew, Steve Holmes
  • Anti-IL-1R1 Single Domain Antibodies And Therapeutic Uses
    Publication number: 20090191217
    Abstract: Disclosed is the use of an antagonist of Interleukin 1 receptor type 1 (IL-1R1) for the manufacture of a medicament treating, preventing or suppressing lung inflammation or a respiratory disease. In some embodiments of the described invention, the medicament is for local administration to pulmonary tissue. Also disclosed are methods for treating lung inflammation or a respiratory disease.
    Type: Application
    Filed: December 1, 2005
    Publication date: July 30, 2009
    Inventors: Ruud M. de Wildt, Philip D. Drew, Ian M. Tomlinson, Mary Fitzgerald, Craig Fox, Steve Holmes
  • Noncompetitive Domain Antibody Formats That Bind Interleukin 1 Receptor Type 1
    Publication number: 20090155283
    Abstract: The invention relates to dAb monomers that bind IL-1R1 and inhibit binding of IL-1 (e.g., IL-1? and/or IL-1?) to the receptor but do not inhibit binding of IL-1ra to IL-1R1, and to ligands comprising such dAb monomers. The invention relates to protease resistand dAb monomers, and to ligands comprising protease resistant dAb monomers. The invention also relates to nucleic acids including vectors that encode the dAb monomers and ligand, to host cells that comprise the nucleic acids and to method for producing a dAb monomer or ligand. The invention also relates to pharmaceutical compositions that comprise the dAb monomers or ligands, and to therapeutic methods that comprise administering a dAb monomer of ligand.
    Type: Application
    Filed: November 30, 2006
    Publication date: June 18, 2009
    Inventors: Philip D. Drew, Rudolf M.T. de Wildt, Ian M. Tomlinson, Amrik Basran
  • Competitive Domain Antibody Formats That Bind Interleukin 1 Receptor Type 1
    Publication number: 20080311111
    Abstract: The invention relates to dAb monomers that bind IL-1R1 and inhibit binding of IL-1 (e.g., IL-1? and/or IL-1?) and IL-1ra to IL-1R1, and to ligands comprising such dAb monomers. The invention relates to protease resist and dAb monomers, and to ligands comprising protease resistant dAb monomers. The invention also relates to nucleic acids including vectors that encode the dAb monomers and ligand, to host cells that comprise the nucleic acids and to method for producing a dAb monomer or ligand. The invention also relates to pharmaceutical compositions that comprise the dAb monomers or ligands, and to therapeutic methods that comprise administering a dAb monomer of ligand.
    Type: Application
    Filed: November 30, 2006
    Publication date: December 18, 2008
    Inventors: Philip D. Drew, Rudolf M.T. De Wildt, Ian M. Tomlinson, Amrik Basran