Abstract: Disclosed is a soft tissue excision apparatus having a handle and an elongated blade support member extending from the handle. The distal end of blade support member includes a first thermally conductive blade support arm and a second thermally conductive blade support arm. An electrically heatable blade is supported at and electrically isolated from the distal ends of the two thermally conductive blade support arms. A first electrically conductive lead extends from the proximal end of the thermally conductive blade support member to a first blade heater contact pad. A second electrically conductive lead extends from the proximal end of the thermally conductive blade support member to a second blade heater contact pad. First and second electrically conductive flexible leads extend from the proximal end of the thermally conductive blade support member to a controller.

Abstract: Thermal cutting surgical instruments incorporate a blade incorporating a first substrate of high thermal conductivity material in the heated portion of the blade and a support and, the first substrate of high thermal conductivity material joined to a second substrate of low thermal conductivity material in the support region of the blade; an electrically insulative dielectric layer disposed on the first surface of the first substrate and on the first surface of second substrate; an electrically resistive heating element disposed on the electrically insulative dielectric; electrically conductive power leads and electrically conductive sense leads disposed on the electrically insulative dielectric layer and that are in electrical communication with the electrically resistive heating element; and an electrically insulative dielectric overcoat layer disposed on the electrically resistive heating element and on the distal portion of the electrically conductive power leads and electrically conductive sense leads.

Abstract: An isothermal cooking plate assembly is formed from a first plate of high thermal conductivity material having a back surface and an oppositely disposed top cooking surface. One or more heater circuit assemblies are disposed on the first plate back surface for forming a composite having a back surface. A controller is in electrical connection with the heater circuit assemblies for controlling temperature of the first plate of high thermal conductivity material. The first plate can be aluminum Type 1100 or aluminum Type 6061. The first plate can be a laminate formed from a clad bottom metal layer and clad top cooking surface metal layer, where the clad layers formed from the same material and having about the same thickness. The clad material can be austenitic stainless steel. A second plate of low thermal conductivity material can be attached to the composite back surface of first plate.

Abstract: The recovery of an intact volume of tissue proceeds with a delivery cannula distal end positioned in confronting adjacency with the volume of tissue to be recovered. A tissue cutting and capture assembly formed of a plurality of metal leafs is deployed from the distal end of the delivery cannula. The tips of these leafs carry a pursing cable assembly, which is electrically excited to electrosurgically cut around and circumscribe the tissue volume. These pursing cables are tensioned to complete the envelopment of the tissue volumes by drawing the leaf tips together. An essential attribute of the disclosed apparatus is the confinement of the path of electrical conduction of constant current required to achieve tissue cutting to only those portions of the deploying and retracting resistively heated portion of the electrically conductive cutting and pursing cable that are in direct contact with tissue.

Abstract: A scan completeness auditing system for screening a volume of tissue comprising a manual image scanning device having an imaging probe, a position tracking system configured to track and record the position of the imaging probe during use, and a controller in communication with the recording system and the manual image scanning device, the controller configured to electronically receive and record the scanned images from the manual image scanning device, and to measure an image-to-image spacing and a scan-to-scan spacing between the scanned images within scan sequence and between scan sequences respectively. The scan completeness auditing system is further adapted to provide an alert to the operator if the image-to-image or scan-to-scan spacing exceeds an acceptable value.

Abstract: The disclosure provides wearable cardiac arrest detection and alerting device that incorporates a non-invasive sensor based on optical and/or electrical signals transmitted into and received from human tissue containing blood vessels, and that transcutaneously quantifies the wearer's heart rate. The heart-rate quantification enables the detection of the absence of any heart beat by the wearable detection and alerting device indicative of the occurrence of a cardiac arrest, wherein the heart is no longer achieving effective blood circulation in the individual wearing the device. The display on the wearable cardiac arrest detection and alerting device may include the elapsed time since the time of detection of a heart rate that is below a predetermine lower limit value, i.e., the detected occurrence of a cardiac arrest event.

Abstract: An isothermal cooking plate assembly is formed from a first plate of high thermal conductivity material having a back surface and an oppositely disposed top cooking surface. One or more heater circuit assemblies are disposed on the first plate back surface for forming a composite having a back surface. A controller is in electrical connection with the heater circuit assemblies for controlling temperature of the first plate of high thermal conductivity material. The first plate can be substantially pure one or more aluminum, substantially pure copper, or aluminum nitride. The first plate can be a laminate formed from a clad bottom metal layer and clad top cooking surface metal layer, where the clad layers formed from the same material and having about the same thickness. The clad material can be austenitic stainless steel. A second plate of low thermal conductivity material can be attached to the composite back surface.

Abstract: An isothermal cooking plate assembly is formed from a first plate of high thermal conductivity material having a back surface and an oppositely disposed top cooking surface. One or more heater circuit assemblies are disposed on the first plate back surface for forming a composite having a back surface. A controller is in electrical connection with the heater circuit assemblies for controlling temperature of the first plate of high thermal conductivity material. The first plate can be substantially pure one or more aluminum, substantially pure copper, or aluminum nitride. The first plate can be a laminate formed from a clad bottom metal layer and clad top cooking surface metal layer, where the clad layers formed from the same material and having about the same thickness. The clad material can be austenitic stainless steel. A second plate of low thermal conductivity material can be attached to the composite back surface.

Abstract: Disclosed is a soft tissue excision apparatus having a handle and an elongated blade support member extending from the handle. The distal end of blade support member includes a first thermally conductive blade support arm and a second thermally conductive blade support arm. An electrically heatable blade is supported at and electrically isolated from the distal ends of the two thermally conductive blade support arms. A first electrically conductive lead extends from the proximal end of the thermally conductive blade support member to a first blade heater contact pad. A second electrically conductive lead extends from the proximal end of the thermally conductive blade support member to a second blade heater contact pad. First and second electrically conductive flexible leads extend from the proximal end of the thermally conductive blade support member to a controller.

Abstract: The disclosure provides a wearable cardiac arrest detection and alerting device that incorporates a non-invasive sensor based on optical and/or electrical signals transmitted into and received from human tissue containing blood vessels, and that transcutaneously quantifies the wearer's heart rate. The heart-rate quantification enables the detection of the absence of any heart beat by the wearable detection and alerting device indicative of the occurrence of a cardiac arrest, wherein the heart is no longer achieving effective blood circulation in the individual wearing the device. The display on the wearable cardiac arrest detection and alerting device may include the elapsed time since the time of detection of a heart rate that is below a predetermine lower limit value, i.e., the detected occurrence of a cardiac arrest event.

Abstract: A scan completeness auditing system for use with an ultrasound imaging console in screening a volume of tissue comprising a location tracking system comprising at least one position sensor adapted to couple to an imaging probe and at least one orientation sensor adapted to couple to the probe, the position and orientation sensors configured to provide data corresponding to the position and orientation of the imaging probe and a receiver comprising a controller configured to receive the position and orientation data from the location tracking system and to electronically receive and record a first scan sequence comprising a first set of scanned images representing cross-sections of the tissue from the imaging probe. The controller can be configured to assign a replay dwell time to each image in the scan sequence. The dwell time for each image can be based on a relative spacing for that image in the scan sequence.

Abstract: A scan completeness auditing system for use with an imaging console in screening a volume of tissue comprising a position tracking system configured to track and record a position of a manual imaging probe. The position tracking system com prises a plurality of cameras adapted to couple to the manual imaging probe and configured to provide position data for the manual imaging probe. The scan completeness auditing system includes a receiver comprising a controller-configured to electronically receive position data for the manual ultrasonic imaging probe from the position tracking system and to electronically receive and record a first scan sequence comprising a first set of scanned images representing cross-sections of the tissue from the manual imaging probe. The controller can be configured to compute an image-to-image spacing between successive images within the first scan sequence and to determine whether the computed image-to-image spacing exceeds a maximum limit.

Abstract: Systems and methods are disclosed for reviewing multiple images while monitoring a reviewer's attentiveness during the review. Systems include an image review system configured to output a series of images to the display and a user attention monitoring system configured to monitor at least one attention parameter for a user during the user's review and to generate user attention data based on the at least one attention parameter monitored, wherein the image review system is configured to output the second image to the display if the user attention data indicates sufficient user attentiveness. The image review system may also be configured to generate distraction or review breaks during the review period.

Abstract: An isothermal cooking plate assembly is formed from a first plate of high thermal conductivity material having a back surface and an oppositely disposed top cooking surface. One or more heater circuit assemblies are disposed on the first plate back surface for forming a composite having a back surface. A controller is in electrical connection with the heater circuit assemblies for controlling temperature of the first plate of high thermal conductivity material. The first plate can be substantially pure one or more aluminum, substantially pure copper, or aluminum nitride. The first plate can be a laminate formed from a clad bottom metal layer and clad top cooking surface metal layer, where the clad layers formed from the same material and having about the same thickness. The clad material can be austenitic stainless steel. A second plate of low thermal conductivity material can be attached to the composite back surface.

Abstract: A system, and apparatus for detecting and quantifying circulatory anomalies, including right-to-left cardiac shunts. The apparatus implements a sensor system useful in connection with a circulatory indicator delivery system. The sensor apparatus is preferably configured with a series of emitter/detector pairs to optimize the sensitivity of detection of the circulating indicator. Sensing of the indicator concentration takes place at an arterial vasculature, for example, the pinna of the human ear. A monitor/controller calculates and displays a indicator/dye dilution curve to assess for the presence of a cardiac shunt. The monitor/controller further corrects the indicator/dilution curve displayed for any recirculation phenomena and can quantify any right-to-left shunt calculated conductance associated with detected shunts.

Abstract: Methods, apparatus and systems for precisely controlling a Valsalva maneuver and the timing thereof in conjunction with testing a patient for a cardiac shunt, and for ensuring that a patient performing a Valsalva maneuver creates a required pressure using their diaphragm. Embodiments of a Valsalva maneuver mouthpiece assembly are also disclosed for use with the invention methods, apparatus and systems. The mouthpiece assembly is adapted to selectively operate between a state that produces resistance to the exhalation pressure of a patient into the mouthpiece and a state wherein the pressure resistance is rapidly removed so as to cause an involuntary exhalation of the air in the patient's lungs at a time of desired Valsalva maneuver release.

Abstract: Systems and methods for detecting circulatory anomalies such as, for example, right-to-left cardiac and pulmonary shunts. A fluorescing indicator is injected into the bloodstream of a subject. An optical sensor is used to transcutaneously excite the indicator into fluorescence and to transcutaneously detect the fluorescence, and a relative concentration of the indicator is determined as a function of time. An indicator dilution curve is generated from the relative concentration readings, the curve shape is analyzed for the indication of a shunt and, if a shunt is detected, a ratiometric area under the curve analysis is performed and combined with a calculated cardiac output value to provide a shunt conductance value. A Valsalva maneuver may be performed as a part of the method. System embodiments may include a controller/monitor that monitors, times, cues and/or analyzes various steps of a shunt detection test.

Abstract: A scan completeness auditing system for screening a volume of tissue comprising a manual image scanning device having an imaging probe, a position tracking system configured to track and record the position of the imaging probe during use, and a controller in communication with the recording system and the manual image scanning device, the controller configured to electronically receive and record the scanned images from the manual image scanning device, and to measure an image-to-image spacing and a scan-to-scan spacing between the scanned images within scan sequence and between scan sequences respectively. The scan completeness auditing system is further adapted to provide an alert to the operator if the image-to-image or scan-to-scan spacing exceeds an acceptable value.

Abstract: A hemostatic surgical blade is described which is formed of five symmetrically disposed layers. A martensitic stainless steel core is provided with oppositely disposed faces which are bonded to hard pure copper thermal transfer layers which, in turn, are supported by buttressing layers of austenitic stainless steel. The blade is heated by a blade heater circuit which is provided as a flexible circuit carrying one or more resistor heaters and associated leads supported by a polyimide substrate. A thermally conductive and electrically insulative adhesive is used to bond the flexible circuit to a blade blank. The system employs a multi-lead cable which is removable from an instrument handle. One blade embodiment involves an elongate stem for accessing body cavities and another embodiment incorporates a controller function within an instrument handle.

Abstract: A system, method and apparatus are disclosed for using a transcutaneous detection system to measure the quantity of a circulating organ activity detection analyte in the blood, and thereby assay the activity of an organ. A preferred organ for assay is the human liver and a preferred indicator is indocyanine green (ICG) dye The procedure is under the control of a monitor/controller having a visual display and capable of providing cues to the operator. A sensor array apparatus for use in conjunction with the system monitor/controller is configured for increased sensitivity of assaying organ function.