Abstract: The present disclosure provides a method of treating a central nervous system disorder in a patient in need thereof. The method comprises orally administering between 75 mg and 300 mg xanomeline salt and between 20 mg and 200 mg trospium chloride to the patient during a 24-hour period, the central nervous system disorder being selected from schizophrenia, Alzheimer's disease, Huntington's disease, Parkinson's disease, and Lewy Body dementia, wherein use of the trospium chloride alleviates a side effect associated with use of the xanomeline salt.

Abstract: According to one embodiment, a product includes a composite film comprising a polymer layer directly adjacent a graphene layer. According to another embodiment, a process includes layering a graphene layer onto a polymer layer to form a composite film.

Abstract: A process includes layering a graphene layer onto a polymer layer to form a composite film.

Abstract: A method of making large ultrathin free-standing polymer films without use of a sacrificial layer includes the steps of providing a substrate, applying a polyelectrolyte material to said substrate, applying a polymer material onto said substrate and onto said polyelectrolyte material, and directly delaminating said polymer material from said substrate and said polyelectrolyte to produce the ultrathin free-standing polymer film.

Abstract: According to one embodiment, a product includes a composite film comprising a polymer layer directly adjacent a graphene layer. According to another embodiment, a process includes layering a graphene layer onto a polymer layer to form a composite film.

Abstract: A method of making large ultrathin free-standing polymer films without use of a sacrificial layer includes the steps of providing a substrate, applying a polyelectrolyte material to said substrate, applying a polymer material onto said substrate and onto said polyelectrolyte material, and directly delaminating said polymer material from said substrate and said polyelectrolyte to produce the ultrathin free-standing polymer film.

Abstract: A method of making large ultrathin free-standing polymer films without use of a sacrificial layer includes the steps of providing a substrate, applying a polyelectrolyte material to said substrate, applying a polymer material onto said substrate and onto said polyelectrolyte material, and directly delaminating said polymer material from said substrate and said polyelectrolyte to produce the ultrathin free-standing polymer film.

Abstract: A method for reducing the density of sites on the surface of fused silica optics that are prone to the initiation of laser-induced damage, resulting in optics which have far fewer catastrophic defects, and are better capable of resisting optical deterioration upon exposure to a high-power laser beam.

Abstract: A method for reducing the density of sites on the surface of fused silica optics that are prone to the initiation of laser-induced damage, resulting in optics which have far fewer catastrophic defects, and are better capable of resisting optical deterioration upon exposure to a high-power laser beam.

Abstract: A method for purifying metallic alloys of uranium for use as nuclear reactor fuels in which the metal alloy is first converted to an oxide and then dissolved in nitric acid. Initial removal of metal oxide impurities not soluble in nitric acid is accomplished by filtration or other physical means. Further purification can be accomplished by carbonate leaching of uranyl ions from the partially purified solution or using traditional methods such as solvent extraction.

Abstract: The invention is a specialized reaction cell for converting uranium metal to uranium oxide. In a preferred form, the reaction cell comprises a reaction chamber with increasing diameter along its length (e.g. a cylindrical chamber having a diameter of about 2 inches in a lower portion and having a diameter of from about 4 to about 12 inches in an upper portion). Such dimensions are important to achieve the necessary conversion while at the same time affording criticality control and transportability of the cell and product. The reaction chamber further comprises an upper port and a lower port, the lower port allowing for the entry of reactant gasses into the reaction chamber, the upper port allowing for the exit of gasses from the reaction chamber. A diffuser plate is attached to the lower port of the reaction chamber and serves to shape the flow of gas into the reaction chamber.

Abstract: A method of mounting a thermocouple assembly on a surface of a metal member by fusion welding of the thermocouple assembly sheath to the metal surface whereby the welding operation can be entirely carried out from a remote location either in air or in an underwater environment. The method generally comprises: positioning the thermocouple assembly so that the axis of the sheath extends perpendicular to the surface of the metal member, pressing the thermocouple assembly against the surface of the metal member so that the outer end surface of the tip portion of the sheath contacts the surface of the metal member; and fusion welding the tip portion to the surface of the metal member by connecting a source of d.c. potential across the sheath and the metal member and passing a d.c. current through the metal sheath and the metal member for a desired period of time.

Abstract: Strong dimensionally stable high-melting nonwoven fibrous sheets comprised of filaments from an optically anisotropic melt-forming polymer and self-bonded at a plurality of filament cross-over points, and a process for making such sheets.

Abstract: A method for improving the uniformity in visual appearance of a film-fibril nonwoven sheet of thermoplastic polymer comprising passing said sheet through the nip formed between two rolls, one of which has a hot conductive surface with a specified pattern of bosses and the other of which has a surface with a durometer hardness of at least 70 (Shore D scale); applying a specified pressure to the sheet while heating the pattern areas to fuse the film-fibrils together on the surface of the sheet to form transparent windows in the pattern areas without substantially fusing the film-fibrils in the remaining areas of the sheet.