Patents by Inventor Philip Floyd Hughes

Philip Floyd Hughes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS FOR TARGETING HSP90
    Publication number: 20220135572
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.
    Type: Application
    Filed: January 10, 2022
    Publication date: May 5, 2022
    Inventors: Timothy A. J. Haystead, Philip Floyd Hughes
  • Compounds and methods for targeting HSP90
    Patent number: 11261187
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: March 1, 2022
    Assignee: Duke University
    Inventors: Timothy A. J. Haystead, Philip Floyd Hughes
  • Substituted heterocycles for targeting Hsp90
    Patent number: 10927115
    Abstract: Substituted indazoles linked to a substituted adenine with a polyethylene glycol moiety selectively bind to Hsp90. The compounds include detection moieties such as fluorophores and are useful in methods and kits for selective detection of Hsp90 in a sample.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: February 23, 2021
    Assignee: Duke University
    Inventors: Timothy Haystead, Philip Floyd Hughes
  • COMPOUNDS AND METHODS FOR TARGETING HSP90
    Publication number: 20200354365
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.
    Type: Application
    Filed: April 21, 2017
    Publication date: November 12, 2020
    Applicant: Duke University
    Inventors: Timothy A.J. HAYSTEAD, Philip Floyd HUGHES
  • COMPOUNDS AND METHODS FOR TARGETING HSP90
    Publication number: 20200216452
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Application
    Filed: August 26, 2019
    Publication date: July 9, 2020
    Inventors: Timothy Haystead, Philip Floyd Hughes
  • Substituted heterocycles for targeting HSP90
    Patent number: 10442806
    Abstract: Described herein are substituted indazoles comprising formula (II) that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. Formula (II) may link to detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: October 15, 2019
    Assignee: Duke University
    Inventors: Timothy Haystead, Philip Floyd Hughes, Christopher D. Lascola
  • COMPOUNDS AND METHODS FOR TARGETING HSP90
    Publication number: 20190031661
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Application
    Filed: June 5, 2018
    Publication date: January 31, 2019
    Inventors: Timothy Haystead, Philip Floyd Hughes, Christopher D. Lascola
  • Substituted 6-aminopurines for targeting HSP90
    Patent number: 10112947
    Abstract: Described herein are 6-aminopurine compounds comprising formula (III) that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. Formula (III) may link to detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: October 30, 2018
    Assignee: Duke University
    Inventors: Timothy Haystead, Philip Floyd Hughes
  • COMPOUNDS AND METHODS FOR TARGETING HSP90
    Publication number: 20170369491
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Application
    Filed: July 18, 2017
    Publication date: December 28, 2017
    Inventors: Timothy Haystead, Philip Floyd Hughes
  • Substituted indazoles for targeting Hsp90
    Patent number: 9738643
    Abstract: Described herein are substituted indazoles that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 22, 2017
    Assignee: Duke University
    Inventors: Timothy Haystead, Philip Floyd Hughes
  • COMPOUNDS AND METHODS FOR TARGETING HSP90
    Publication number: 20150191471
    Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.
    Type: Application
    Filed: March 14, 2013
    Publication date: July 9, 2015
    Applicant: Duke University
    Inventors: Timothy Haystead, Philip Floyd Hughes
  • Pharmaceutical compounds
    Patent number: 6395735
    Abstract: The present invention provides novel indane-like compounds which can be useful for treating psychosis and other conditions associated with the modulation of a muscarinic receptor. The invention provides formulations and methods for using the novel compounds.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: May 28, 2002
    Assignee: Eli Lilly and Company
    Inventors: Sean Patrick Hollinshead, Philip Floyd Hughes, Jose Serafin Mendoza, Joseph Wendell Wilson, Bret Eugene Huff, Charles Howard Mitch, Michael Alexander Staszak, John Stanley Ward
  • Pharmaceutical compounds
    Publication number: 20010012848
    Abstract: The present invention provides novel indane-like compounds which can be useful for treating psychosis and other conditions associated with the modulation of a muscarinic receptor. The invention provides formulations and methods for using the novel compounds.
    Type: Application
    Filed: December 19, 2000
    Publication date: August 9, 2001
    Inventors: Sean Patrick Hollinshead, Philip Floyd Hughes, Jose Serafin Mendoza, Joseph Wendell Wilson, Bret Eugene Huff, Charles Howard Mitch, Michael Alexander Staszak, John Stanley Ward
  • Potassium channel inhibitors
    Patent number: 6083986
    Abstract: Compounds useful as potassium channel inhibitors and especially useful for the treatment of cardiac arrhythmias and cell proliferative disorders are described.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: July 4, 2000
    Assignees: ICAgen, Inc., Eli Lilly & Company
    Inventors: Neil Alexander Castle, Sean Patrick Hollinshead, Philip Floyd Hughes, Jose Serafin Mendoza, Joseph Wendell Wilson, George Salvatore Amato, Serge Beaudoin, Michael Gross, Grant McNaughton-Smith