Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting expression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.

Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting expression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.

Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting epression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.

Abstract: In one embodiment, an apparatus cascades groups of serialized data streams through devices, and performs operations based on information communicated therein. A received group of serialized data streams is aligned, but not framed, and forwarded to a next device (e.g., a next stage in a linear or tree cascaded formation of devices). Eliminating the framing and subsequent serialization operations performed on the received group of serialized data streams reduces the latency of communications through the cascaded devices, which can be significant when considered in relation to the high-speed communication rates. The received group of serialized data streams is also framed to create a sequence of data frames for processing (e.g., associative memory lookup operations, controlling multiplexing of received downstream serialized data streams, general or other processing) within the device.

Abstract: In one embodiment, an apparatus cascades groups of serialized data streams through devices, and performs operations based on information communicated therein. A received group of serialized data streams is aligned, but not framed, and forwarded to a next device (e.g., a next stage in a linear or tree cascaded formation of devices). Eliminating the framing and subsequent serialization operations performed on the received group of serialized data streams reduces the latency of communications through the cascaded devices, which can be significant when considered in relation to the high-speed communication rates. The received group of serialized data streams is also framed to create a sequence of data frames for processing (e.g., associative memory lookup operations, controlling multiplexing of received downstream serialized data streams, general or other processing) within the device.

Abstract: Disclosed is a fluid catalytic cracking apparatus. The apparatus includes means for decreasing and increasing the slip velocity of a hydrocarbon reaction stream to further enhance catalytic cracking of the hydrocarbon within the reaction stream. The apparatus allows for control of residence time within both a riser and a collection and velocity reducing means to provide for more complete cracking of the hydrocarbon without leading to additional coking of the catalytic cracking catalyst.

Abstract: A method and apparatus are described for contacting solid particles and fluid. A liquid is sprayed as liquid droplets from the discharge tip of a nozzle into hot solid particles passing upwardly in a vertical pipe. A venturi is formed in the pipe, and the venturi has an entrance portion which is upwardly convergent to the throat and an exit portion which is upwardly divergent from the throat. The tip of the nozzle is so located relative to the venturi that liquid droplets commence vaporization, due to heat transfer from the hot solid particles, no further up stream (relative to the direction of movement of solid particles up the pipe) than the throat of the venturi thereby resulting in a high degree of turbulence which causes good mixing of particles and vapor downstream of the venturi throat. The particles-vapor mixture leaving the exit portion of the venturi is well mixed and particles are substantially uniformly mixed with vapor in radial planes of the pipe downstream of the venturi.

Abstract: Disclosed is a system for fluid catalytic cracking. The system includes a method and means for decreasing and increasing the slip velocity of a hydrocarbon reaction stream to further enhance catalytic cracking of the hydrocarbon within the reaction stream. The system also allows for control of residence time within both a riser and a collection and velocity reducing means to provide for more complete cracking of the hydrocarbon without leading to additional coking of the catalytic cracking catalyst.

Abstract: A catalytic cracking process and apparatus wherein particles of cracking catalyst circulate continuously between a reaction zone and a regeneration zone and hot regenerated catalyst from the regeneration zone contacts hydrocarbon feed in the reaction zone to produce cracked hydrocarbon products and spent catalyst. The spent catalyst is recovered and subjected to stripping in a stripping zone to remove strippable material therefrom. The stripped spent catalyst is circulated to the regeneration zone for oxidative exothermic regeneration. Some hot regenerated catalyst is passed directly from the regenerator to the stripping zone via a conduit provided for this purpose. Another hydrocarbon stream is passed into contact with the hot regenerated catalyst in this conduit. The said other hydrocarbon stream is converted to products of enhanced value (e.g., olefins) during contact with catalyst in the conduit, and the said products are recovered.