Abstract: An infusion set for subcutaneous delivery of an infusant. The infusion set may include a base removably attachable to an infusion site and a connector temporarily lockable to the base. The connector can engage the base in a plurality of orientations. The connector locks into the base after at least partial rotation of the connector about the base. The connector may include flexible arms which unlock the connector from the base. The base includes a cannula for insertion through the infusion site. The connector includes a tubing for passing the infusant. The infusant is subcutaneously passable from the tubing through the cannula when the connector is attached to the base. The infusion set may also include a hub removably attachable to the base that includes a needle that extends through the base and the cannula and a guard removably attachable to the base opposite the hub for surrounding the needle.

Abstract: A reservoir, made from a cyclic olefin copolymer (COC), for containing a fluid for infusion into a body of a patient includes a proximal end adapted to connect to an infusion set, a distal end, a cylindrical wall longitudinally extending from the proximal end to the distal end, and a piston adapted to be slidably mounted within the reservoir at the distal end. The COC may be Topas® and the reservoir may be used to contain insulin. The piston forms a fluid tight seal and may be connected to a linear actuation member. Additionally, the piston may be formed from an elastomeric material including rubber, silicone, bromobutyl, natural synthetic isoprene, nitrile, and/or ethylene propylene diene monomers. The piston may also be made from a COC such as Topas®.

Abstract: A multiple layer tubing for conveying a fluidic media in a medical or laboratory environment includes at least one outer layer of a copolyester ether (COPE) material. The tubing also includes an inner layer of a material compatible with sensitive fluidic media and at least one intermediate layer for bonding the outer layer to the inner layer. The material of the inner layer may be a high density polyethylene or a polyurethane material. The material of the intermediate layer may be ethylene-vinyl acetate (EVA). With the use of a COPE outer layer, a multiple layer medical tubing may be made without polyvinylchloride (PVC) or PVC plasticizers. The multiple layer tubing may be made by extrusion. The three layers may be co-extruded, simultaneously, as part of an efficient manufacturing processes.