Patents by Inventor Philip HUMPHREYS

Philip HUMPHREYS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS
    Publication number: 20190202799
    Abstract: Compounds of formula (I) and salts thereof: wherein R1, R2, R3, a, X1, X2, X3, X4, and X5 are as defined hereinbefore. Compounds of formula (I) and salts thereof have been found to inhibit the binding of the BET family of bromodomain containing proteins to, for example, acetylated lysine residues and thus may have use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis; and cancers.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 4, 2019
    Inventors: Andrew BAXTER, Rino Antonio BIT, John Alexander BROWN, David HIRST, Philip HUMPHREYS, Katherine Louise JONES, Vipulkumar Kantibhai PATEL
  • IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS
    Publication number: 20190175571
    Abstract: Compounds of formula (I) and salts thereof: wherein R1, R2, R3 and a are as defined herein. Compounds of formula (I) and salts thereof have been found to inhibit the binding of the BET family of bromodomain containing proteins to, for example, acetylated lysine residues and thus may have use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis; and cancers.
    Type: Application
    Filed: August 31, 2017
    Publication date: June 13, 2019
    Inventors: Andrew BAXTER, John Alexander BROWN, David HIRST, Philip HUMPHREYS, Katherine Louise JONES, Vipulkumar Kantibhai PATEL