Patents by Inventor Philip J. Beeby

Philip J. Beeby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cephalosporin type antibacterials
    Patent number: 4139618
    Abstract: 3-[3-(methyl-1,3,4-thiadiazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha.-s ubstituted acetamido)-ceph-3-em-4-carboxylic acids; 3-[3-(3-methyl-1,2,4-thiadiazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha .-substituted acetamido)-ceph-3-em-4-carboxylic acids; and 3-[3-(2-methyl-1,3,4-oxadiazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha. -substituted acetamido)-ceph-3-em-4-carboxylic acids and derivatives and salts thereof and processes for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.
    Type: Grant
    Filed: June 28, 1976
    Date of Patent: February 13, 1979
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Philip J. Beeby
  • Cephalosporin type antibacterials having a substituted propenyl group in the 3-position
    Patent number: 4112087
    Abstract: Compounds of the formula ##STR1## wherein R is alkyl having 1 to 4 carbon atoms, .beta.-haloethyl, allyl, propargyl, cyclopentyl or benzyl; R.sup.1 is hydrogen or an .alpha.-substituted acetamido group; R.sup.2 is hydrogen or a protecting group; and the pharmaceutically acceptable salts thereof. The 7.beta.-amino compounds are useful as intermediates for the 7.beta.-(.alpha.-substituted acetamido) compounds which are useful as antibacterials against a wide variety of gram positive and gram negative bacteria.
    Type: Grant
    Filed: November 4, 1976
    Date of Patent: September 5, 1978
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Philip J. Beeby
  • 3-Propenyl derivatives of cephalosporin, compositions and their use
    Patent number: 4094978
    Abstract: 3-(3-hydroxyprop-1-(t)-enyl)-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids; 3-(3-carbamoyloxyprop-1-(t)-enyl)-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids; and 3-[3-(N-substituted carbamoyloxy)prop-1-(t)-enyl]-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids and derivatives and salts thereof and process for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.
    Type: Grant
    Filed: July 29, 1976
    Date of Patent: June 13, 1978
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Philip J. Beeby
  • Cephalosporin type antibacterials
    Patent number: 4049806
    Abstract: 3-[3-(1-Methyltetrazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha.-phenylac etamido)-ceph-3-em-4-carboxylic acid; 7.beta.-(.alpha.-phenylacetamido)-3-[3-(1,2,4-triazol-5-ylthio)-prop-1-(t) -enyl]-ceph-3-em-4-carboxylic acid derivatives and salts thereof; and intermediates and processes for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.
    Type: Grant
    Filed: August 15, 1975
    Date of Patent: September 20, 1977
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Philip J. Beeby
  • Cephalosporin type antibacterials
    Patent number: 3983113
    Abstract: 3-[3-(1-Methyltetrazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha.-substitu ted acetamido)-ceph-3-em-4-carboxylic acid; 7.beta.-(.alpha.-substituted acetamido)-3-[3-(1,2,4-triazol-5-ylthio)-prop-1-(t)-enyl]-ceph-3-em-4-carb oxylic acid derivatives and salts thereof; and ester intermediates and processes for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.
    Type: Grant
    Filed: October 14, 1975
    Date of Patent: September 28, 1976
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Philip J. Beeby