Abstract: A method of conducting oxidation in an inflatable bag bioreactor or a batch reactor is provided. The inflatable bag bioreactor or the batch reactor is used as an efficient, economical, and convenient reaction vessel. The inflatable bag bioreactor or batch reactor is rotated or rocked during the reaction to ensure continued exposure of the reaction mixture to the headspace gas in the vessel. The ability of the inflatable bag to expand or contract as the volume of the contents changes helps maintain consistent pressure and avoids the need to replenish the headspace gas.

Abstract: Conducting oxidation in an inflatable bag bioreactor (or batch reactor more generally) provides an efficient, economical, and convenient reaction vessel. Rotating or rocking the inflatable bag bioreactor (or batch reactor more generally) during the reaction helps ensure continued exposure of the reaction mixture to the headspace gas in the vessel. The ability of the inflatable bag to expand or contract as the volume of the contents changes helps maintain consistent pressure and avoid the need to replenish the headspace gas.

Abstract: Conducting oxidation in an inflatable bag bioreactor (or batch reactor more generally) provides an efficient, economical, and convenient reaction vessel. Rotating or rocking the inflatable bag bioreactor (or batch reactor more generally) during the reaction helps ensure continued exposure of the reaction mixture to the headspace gas in the vessel. The ability of the inflatable bag to expand or contract as the volume of the contents changes helps maintain consistent pressure and avoid the need to replenish the headspace gas.