Patents by Inventor Philip J. Lee

Philip J. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11938536
    Abstract: Metal powder particles for use in additive manufacturing are made by removing material from the surface of the particles using wet chemical etching to create a nanoscale texturing of the surface, increasing absorptivity by the metal powder particles of incident laser light and maintaining flowability. The nanoscale texturing has sub-wavelength features at laser wavelengths in the range 800-1100 nm. The particles are substantially spherical and have mean diameters in the range 10-70 ?m.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: March 26, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Ottman A. Tertuliano, Philip J. DePond, Andrew Curtis Lee, Xun Gu, Wei Cai, Adrian J. Lew
  • Publication number: 20240080905
    Abstract: Methods, devices and systems are provided for performing a random access (RA) procedure. A wireless transmit/receive unit (WTRU) may be configured to receive RA resource sets, where each of the RA resource sets is associated with a node-B directional beam, select an RA resource set from among the RA resource sets, and initiate an RA procedure based on the selected RA resource set. The RA procedure may include selecting multiple preambles which include a preamble for each resource of a plurality of resources corresponding to the selected RA resource set. The WTRU may be configured to sequentially transmit the selected multiple preambles in sequential RA transmissions, and may be configured to receive, from a node-B, in response to the RA transmissions, at least one RA response (RAR), where each of the received at least one RAR corresponds to one of the transmitted multiple preambles.
    Type: Application
    Filed: November 2, 2023
    Publication date: March 7, 2024
    Applicant: InterDigital Patent Holdings, Inc.
    Inventors: Tao DENG, Philip J. Pietraski, Ravikumar V. Pragada, Yugeswar Deenoo, Janet A. Stern-Berkowitz, Moon-il Lee, Mihaela C. Beluri, Kyle Jung-Lin Pan
  • Patent number: 11034925
    Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: June 15, 2021
    Assignee: EMD Millipore Corporation
    Inventors: Paul J. Hung, Philip J. Lee
  • Patent number: 10843189
    Abstract: Methods and systems are described for improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: November 24, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Paul J. Hung, Philip J. Lee, Luke P. Lee
  • Publication number: 20200208089
    Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
    Type: Application
    Filed: December 13, 2019
    Publication date: July 2, 2020
    Inventors: Paul J. Hung, Philip J. Lee
  • Patent number: 10526572
    Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: January 7, 2020
    Assignee: EMD Millipore Corporaticn
    Inventors: Paul J. Hung, Philip J. Lee
  • Publication number: 20190106664
    Abstract: Method and systems that provide improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays.
    Type: Application
    Filed: March 19, 2018
    Publication date: April 11, 2019
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Paul J. Hung, Philip J. Lee, Luke P. Lee
  • Patent number: 10190085
    Abstract: A micro-incubator manifold for improved microfluidic configurations and systems and methods of manufacture and operation for a manifold and automated microfluidic systems are disclosed. Various embodiments relate to assays, systems, and/or devices for culturing cells or other biologic material in controlled environments and are applicable to related fields generally using microfluidic systems. Particular embodiments involve configurations that can be used with various standard automated handling systems, with active or passive loading and perfusion of medium and to provide high-throughput multi-assay automated systems for culturing, viewing, and analyzing cell growth, invasion, movement, chemotaxis or other properties. More specifically, specific embodiments relate to heat control systems for microfluidic culture plates and other automated systems for culture plates.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: January 29, 2019
    Assignee: EMD Millipore Corporation
    Inventors: Philip J. Lee, Terry Gaige, Wei Hsuan (Jessie) Ho
  • Patent number: 10179897
    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation for a microfluidic invasion assay system.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: January 15, 2019
    Assignee: EMD Millipore Corporation
    Inventors: Ju-Sung Paul Hung, Philip J. Lee, Amedeo J. Cappione
  • Patent number: 10138453
    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for independent cell culture systems in a cell culture array. In a second aspect, artificial sinusoids with artificial epithelial barriers are provided with just one (optionally shared or multiplexed) fluidic inlet and one (optionally shared or multiplexed) fluidic output, where the medium output also functions as a cellular input. A pneumatic cell loader combined with other components provides a fully automated cell culture system. Magnetic alignment of plate molds provides advantages and ease of molded manufacture.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: November 27, 2018
    Assignee: EMD Millipore Corporation
    Inventors: Paul J. Hung, Philip J. Lee
  • Patent number: 9969963
    Abstract: Methods and systems are described for improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: May 15, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Paul J. Hung, Philip J. Lee, Luke P. Lee
  • Publication number: 20170267961
    Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 21, 2017
    Inventors: Paul J. Hung, Philip J. Lee
  • Patent number: 9637715
    Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
    Type: Grant
    Filed: April 1, 2012
    Date of Patent: May 2, 2017
    Assignee: EMD Millipore Corporation
    Inventors: Paul J. Hung, Philip J. Lee
  • Publication number: 20160340630
    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation for a microfluidic invasion assay system.
    Type: Application
    Filed: May 23, 2016
    Publication date: November 24, 2016
    Inventors: Ju-Sung Paul Hung, Philip J. Lee, Amedeo J. Cappione
  • Publication number: 20160333298
    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation.
    Type: Application
    Filed: June 7, 2016
    Publication date: November 17, 2016
    Inventors: Paul J. Hung, Philip J. Lee
  • Publication number: 20160312166
    Abstract: A micro-incubator manifold for improved microfluidic configurations and systems and methods of manufacture and operation for a manifold and automated microfluidic systems.
    Type: Application
    Filed: May 25, 2016
    Publication date: October 27, 2016
    Inventors: Philip J. Lee, Terry Gaige, Wei Hsuan (Jessie) Ho
  • Patent number: 9428723
    Abstract: A micro-incubator manifold for improved microfluidic configurations and systems and methods of manufacture and operation for a manifold and automated microfluidic systems.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: August 30, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Philip J. Lee, Terry Gaige, Wei Hsuan (Jessie) Ho
  • Patent number: 9388374
    Abstract: In one embodiment, a microfluidic structure comprises a culture chamber having an object flow inlet disposed between a pair of object flow outlets. A flow-around channel provides fluidic mass transport to the culture chamber through a perfusion barrier disposed opposite from the object flow inlet and object flow outlets. The perfusion barrier surrounds the culture chamber, defines an opposite wall of the culture chamber, and prevents cell passage into the flow around-channel. The perfusion barrier creates a low fluidic resistance path within the culture chamber, such that a flow of cells entering the culture chamber from the object flow inlet encounters a flow of media passing through the perfusion barrier. This causes the cells to take an approximately 180 degree turn and exit the culture chamber via the object flow outlets. The low fluidic resistance path allows the cells to settle onto the chamber floor without needing any physical barrier.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: July 12, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Paul J. Hung, Philip J. Lee
  • Patent number: 9376658
    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for independent cell culture systems in a cell culture array. In a second aspect, artificial sinusoids with artificial epithelial barriers are provided with just one (optionally shared or multiplexed) fluidic inlet and one (optionally shared or multiplexed) fluidic output, where the medium output also functions as a cellular input. A pneumatic cell loader combined with other components provides a fully automated cell culture system. Magnetic alignment of plate molds provides advantages and ease of molded manufacture.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: June 28, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Paul J. Hung, Philip J. Lee
  • Patent number: 9353343
    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation for a microfluidic invasion assay system.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: May 31, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Ju-Sung Paul Hung, Philip J. Lee, Amedeo J. Cappione