Patents by Inventor Philip J. Stephens

Philip J. Stephens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180371099
    Abstract: The present invention provides therapeutic and diagnostic methods and compositions for cancer, for example, bladder cancer. The invention provides methods of treating bladder cancer, methods of determining whether a patient suffering from bladder cancer is likely to respond to treatment comprising a PD-L1 axis binding antagonist, methods of predicting responsiveness of a patient suffering from bladder cancer to treatment comprising a PD-L1 axis binding antagonist, and methods of selecting a therapy for a patient suffering from bladder cancer, based on somatic mutation levels of genes of the invention (e.g., somatic mutation levels in a tumor sample obtained from the patient).
    Type: Application
    Filed: August 28, 2018
    Publication date: December 27, 2018
    Inventors: Richard BOURGON, David FABRIZIO, Gregg FINE, Garrett M. FRAMPTON, Priti HEGDE, Sanjeev MARIATHASAN, Philip J. STEPHENS, James Xin SUN, Roman YELENSKY
  • Publication number: 20180363066
    Abstract: Methods of evaluating tumor mutational burden in a sample, e.g., a tumor sample or a sample derived from a tumor, from a subject, are disclosed.
    Type: Application
    Filed: August 28, 2018
    Publication date: December 20, 2018
    Inventors: Zachary R. Chalmers, Caitlin F. Connelly, David Fabrizio, Garrett Michael Frampton, Priti Hegde, Marcin Kowanetz, Philip J. Stephens, James Xin Sun, Roman Yelensky
  • Publication number: 20140336943
    Abstract: Various embodiments provide interfaces to access genomic testing information and incorporate it into daily physician practice. In some embodiments, presentation of genomic alteration data is simplified and/or coupled with contextual applications. Volumes of genomic alterations and associated information (e.g., journal articles, clinical trial information, therapies, etc.) are analyzed and synthesized into actionable information items viewable on an alteration system. According to one embodiment, the system can be configured to focus practitioners on discrete portions of the alteration information on which they can act. According to other aspects, curated information is provided on the system to enable practitioners to make informed decisions regarding the implications of the presence of specific genomic alterations.
    Type: Application
    Filed: January 3, 2014
    Publication date: November 13, 2014
    Inventors: Michael Pellini, Gary Palmer, Mary P. Lancelotta, Matthew J. Hawryluk, Philip J. Stephens
  • Patent number: 6261103
    Abstract: An interactive computer system for teaching laboratory-based sciences. According to one embodiment, the system includes a data acquisition module, an internet-based coursework database, and internet-based interactive software tools. Using the interactive software tools, an instructor can select academic course materials and related laboratory experiments from the coursework database. The instructor can create an Internet web page, which provides students with an interactive visual interface with the selected course materials and laboratories, along with various analysis tools. The data acquisition module is located at the site of an experimentation laboratory, and interfaces with laboratory equipment to capture data from selected experiments. Experimental data is transmitted in real-time to an internet-based storage location.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: July 17, 2001
    Assignee: CB Sciences, Inc.
    Inventors: Philip J. Stephens, Christopher J. Dufort, Clifford C. Bredenberg, Ashish More, William P. Mitchell