Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A layer structure for a thin-film solar cell and production method are provided. The layer structure for the thin-film solar cell includes a photovoltaic absorber layer doped, at least in a region which borders a surface of the photovoltaic absorber layer, with at least one alkali metal. The layer structure has an oxidic passivating layer on the surface of the photovoltaic absorber layer, which is designed to protect the photovoltaic absorber layer from corrosion.

Abstract: A pressure cuff or garment for prophylactic treatment of deep vein thrombosis includes a series of three chambers arranged in series and coupled fluidically to one another by bleed tubes or chokes. The chambers are otherwise sealed to the environment, save for the first chamber which also provides an inlet/outlet for coupling to a fluid pump. The chambers are also of curved shape so as to overlap one another. The cuff or garment provides more effective pulsating pressure treatment than prior art structures.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A method and system for auto recognition of at least one standoff target to determine position information for a mobile machine. One example automatically scans for at least one standoff target. A location for the at least one standoff target is determined. In addition, a distance and direction between the mobile machine and the at least one standoff target is generated. The location information for the at least one standoff target and the distance and direction between the mobile machine and the at least one standoff target is utilized to provide a position for the mobile machine.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: In one embodiment, a method includes identifying at least one transaction-path node as a problem node based, at least in part, on an analysis of end-to-end response times for a group of transactions. The method further includes determining one or more event types for the at least one transaction-path node. Also, the method includes, for each of the one or more event types, inferring a first event-relevance weight from an abstract model. The method also includes, for each of the one or more event types, inferring a second event-relevance weight from a concrete model. Furthermore, the method includes, for each of the one or more event types, determining an event relevance based, at least in part, on the first event-relevance weight and the second event-relevance weight. Additionally, the method includes identifying most-relevant events among a set of active events based, at least in part, on the determined event relevance.

Abstract: A biomimetic skin for an animatronic figure and other applications is provided. The biomimetic skin may include an outer layer having a surface texture, and an inner layer attached to the outer layer. The inner layer may include a compressible cellular material. The outer layer may move correspondingly with the inner layer such that as the inner layer is moved the outer layer moves.

Abstract: The present disclosure includes a method for altering one or more properties of a primary material. The method includes reducing the elasticity of a primary material and creating a delivery aperture through an outer layer of the primary material. Once the delivery aperture is created, or as the delivery aperture is created, introducing through the delivery aperture a secondary material into a sublayer of the primary material and applying a closure treatment to the primary material to close the delivery aperture. The secondary material includes one or more properties that are different from the primary material. By introducing the secondary material into the primary material, the secondary material locally changes the properties of the primary material. Examples of the variable properties include color, strength, flexibility, magnetism, and optical.

Abstract: An input device (10) comprises a panning mechanism (12). The panning mechanism comprises a sensor arrangement having first and second sensor components (46, 48), a movable carrier arrangement (40) for carrying the first sensor component and a fixed carrier arrangement (42) on which the second sensor component is mounted. The movable carrier arrangement is movable relative to the fixed carrier arrangement. The panning mechanism further includes constraining means (50) to constrain movement of the movable carrier arrangement relative to the fixed carrier arrangement in two directions. The movement of the movable carrier arrangement relative to the fixed carrier arrangement effects movement of the first sensor component relative to the second sensor component to create input signals such as input signals for a data processing apparatus.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A layer structure for a thin-film solar cell and production method are provided. The layer structure for the thin-film solar cell includes a photovoltaic absorber layer doped, at least in a region which borders a surface of the photovoltaic absorber layer, with at least one alkali metal. The layer structure has an oxidic passivating layer on the surface of the photovoltaic absorber layer, which is designed to protect the photovoltaic absorber layer from corrosion.

Abstract: The invention relates to compounds in the treatment or prevention of disorders associated with Lamin A and/or Lamin C depletion or LMNA mutations, such as laminopathy, premature ageing disorders, normal ageing and cancer (such as a cancer characterized by low levels of LMNA expression).

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: The invention relates to compounds in the treatment or prevention of disorders associated with Lamin A and/or Lamin C depletion or LMNA mutations, such as laminopathy, premature ageing disorders, normal ageing and cancer (such as a cancer characterised by low levels of LMNA expression).

Abstract: Embodiments of the present invention are directed to systems for performing non-contact based determination of the position of an implement. In one embodiment, a non-contact based measurement system is used to determine the relative position of an implement coupled with a mobile machine. The geographic position of the mobile machine is determined and the geographic position of said implement based upon the geographic position of the mobile machine and the position of the implement relative to the mobile machine.

Abstract: The present disclosure includes a method for altering one or more properties of a primary material. The method includes reducing the elasticity of a primary material and creating a delivery aperture through an outer layer of the primary material. Once the delivery aperture is created, or as the delivery aperture is created, introducing through the delivery aperture a secondary material into a sublayer of the primary material and applying a closure treatment to the primary material to close the delivery aperture. The secondary material includes one or more properties that are different from the primary material. By introducing the secondary material into the primary material, the secondary material locally changes the properties of the primary material. Examples of the variable properties include color, strength, flexibility, magnetism, and optical.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A biomimetic skin for an animatronic figure and other applications is provided. The biomimetic skin may include an outer layer having a surface texture, and an inner layer attached to the outer layer. The inner layer may include a compressible cellular material. The outer layer may move correspondingly with the inner layer such that as the inner layer is moved the outer layer moves.