Abstract: The present invention is directed to 4?-substituted nucleoside derivatives of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC. The present invention also provides processes for the preparation of 4?-substituted nucleoside derivatives of Formula I and derivatives thereof.

Abstract: The present invention is directed to 4?-substituted nucleoside derivatives of Formula (I) and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC. The present invention also provides processes for the preparation of 4?-substituted nucleoside derivatives of Formula (I) and derivatives thereof.

Abstract: An enantioselective route to compounds of formula I is disclosed: The compounds of formula I are key intermediates in the synthesis of compounds useful in treatment of Alzheimer's disease.

Abstract: A landing gear monitor for aircraft landing gear including a plurality of pairs of wheels on a bogie, in which the main strut oil pressure serves to indicate landing load and is monitored in relation to, respectively, the two-wheel mode and the four-wheel mode, the two-wheel mode being the condition when a first of the plurality of pairs of wheels on the bogie contacts the ground and the four-wheel mode being the condition of a first and a second of the plurality of pairs of wheels on the bogie being in full contact with the ground.

Abstract: The present invention relates to the synthesis of intermediates for the preparation of compounds of formula (A): wherein n is 2 or 3 and various salt forms of these compounds.

Abstract: A continuous power system assembly is provided that includes an integrated shaft-driven unit. The unit contains a turbine, an alternator, a flywheel and a feed pump, all of which are coupled to the shaft. During various modes of operation, any of the turbine, alternator or flywheel may provide the torque used to drive the shaft. When the alternator is not providing the necessary torque to drive the shaft, it is operated as a generator that provides back-up power to a load. The present invention also includes a unique nozzle design that improves the ease with the nozzles may be manufactured in comparison to known designs. The nozzle is manufactured as two halves which are mated as part of the manufacturing process. The individual nozzles may, because only half of the nozzle segments exist on either half of the nozzle block, be easily manufactured using conventional machining.

Abstract: Memory system having contiguous storage locations with sequential addresses is partitioned into units to permit separate unit write-in and parallel unit read-out, operations. Each unit is responsive to common word address signals and unique combinations of block address signals. In response to a control signal in a first of two possible states, the memory system operates in a conventional manner, i.e., data is read from or written to a particular location in the memory to or from a data bus, the address of the particular location being supplied over an address bus and having a block select portion and a word select portion. When the control signal is in its second state, each unit is responsive only to the word address signals to read data from or write data to common word locations in each unit simultaneously.