Abstract: Methods and devices for controlling arbitration in an implantable medical device capable of issuing therapy stimulus for a plurality of therapy programs. The system defines a therapy program at multiple levels including pulse programs, aggregate instructions, and therapy programs. Holdoff and/or arbitration settings are available at several levels of the therapy program definition, allowing increased flexibility and control.

Abstract: An implantable neurostimulation device is configured with a current delivery architecture having at least two digital to analog converters (DACs), and a therapy definition circuit using therapy configurations is provided that allows two therapy configurations to be linked together. When two therapy configurations are linked, each therapy configuration uses a different one of the DACs to deliver therapy in overlapping or simultaneous fashion, using identical or different electrodes.

Abstract: A system may include data acquisition circuitry, local extremum detection circuitry, difference monitoring circuitry, comparator circuitry and extremum data recorder circuitry. The data acquisition circuitry may be configured to access a series of data samples from a sensor signal. The local extremum detection circuitry may be configured to find a local extremum in the series of data samples. The difference monitoring circuitry may be configured to determine a difference between the local extremum and the series of data samples subsequent to and receding from the local extremum toward the first direction. The comparator circuitry may be configured to compare the difference to a predefined threshold. The extremum data recorder circuitry may be configured to write extremum data into storage when the difference exceeds the predefined threshold.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. The aggregate programs also include an amplitude modulation factor that modulates the amplitude defined by the pulse program. The inclusion of an amplitude modulation factor in the aggregate program allows complex amplitude-modulated waveforms to be produced. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. The aggregate programs also include an amplitude modulation factor that modulates the amplitude defined by the pulse program. The inclusion of an amplitude modulation factor in the aggregate program allows complex amplitude-modulated waveforms to be produced. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: An electrical stimulation system includes at least one electrical stimulation lead having stimulation electrodes; and a processor coupled to the at least one electrical stimulation lead to perform actions, including: directing delivery of at least one stimulation pulse to tissue of a patient during each charge injection phase, where each consecutive pair of the charge injection phases is separated by a charge recovery phase; and, for at least one stimulation pulse: during delivery of the stimulation pulse, directing application of at least one charge recovery pulse to interrupt the delivery of the stimulation pulse, where each one of the at least one charge recovery pulse has a relative amplitude that is larger in magnitude than an amplitude of the stimulation pulse; and, after application of the charge recovery pulse, directing resumption of delivery of the stimulation pulse at the amplitude of the stimulation pulse.

Abstract: A system may include a stimulator, sensing circuitry and a controller. The stimulator may be operably connected to at least one stimulation electrode, and configured to deliver an electrical waveform for an electrical therapy using the at least one stimulation electrode. The sensing circuitry may be operably connected to at least one sensing electrode, and configured to sense electrical potentials that are evoked by the electrical waveform to provide sensed evoked signals. The controller may be operably connected to the stimulator and the sensing circuitry. The controller may be configured to automatically define a sampling window, sample the sensed evoked potentials during the sampling window to provide sampled values, detect at least one feature from the sampled values, and automatically provide feedback for closed-loop control of the electrical therapy based on the at least one feature.

Abstract: A system may include an implantable device and a controller. The implantable device may include sensing-capable electrodes. The controller may be configured to receive a trigger signal indicative of a trigger to evaluate sensing capabilities of the sensing capable electrodes, respond to the received trigger signal by evaluating the sensing capabilities of the sensing-capable electrodes to assess or reassess which of the sensing-capable electrodes are available to be activated for sensing ECAPs, activate at least one of the sensing-capable electrodes that are available to be activated based on the evaluating the sensing capabilities, and sense the ECAPs using the activated ones of the sensing-capable electrodes.

Abstract: The present disclosure provides temperature reactive acoustic particles comprising nitrate esters, organic peroxides, organic azides, nitro compounds, organic nitroamines, or mixtures thereof, which react when exposed to a certain temperature for a certain amount of time generating an acoustic signal. The acoustic signal can be used to generate a geographic evaluation of a geologic formation.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. The aggregate programs also include an amplitude modulation factor that modulates the amplitude defined by the pulse program. The inclusion of an amplitude modulation factor in the aggregate program allows complex amplitude-modulated waveforms to be produced. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Improved circuitry for measuring analog values in an implantable pulse generator is disclosed. The measurement circuitry executes instructions that define the timing and parameters of measurements to be taken. The instructions include instructions that are responsive to different types of triggers issued by different pulse definition circuits, which pulse definition circuits generate different stimulation waveforms at different groups of electrodes. The measurement circuitry is configurable to update the groups of electrodes used to deliver stimulation.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.

Abstract: Production of 2,4,6-triamino-1,3,5-trinitrobenzene (TATB) through a safer, less harmful process while yielding a superior product is disclosed. The biphasic production process may include mixing a solution of 1,3,5-trichloro-2,4,6-trinitrobenzene (TCTNB) and a surfactant into a solvent in a sealed, heated vessel such that TATB is formed in a mixture. The biphasic production process may also include pressurizing the vessel with gaseous ammonia such that aqueous TATB is formed and separating the TATB from the mixture.

Abstract: Aspects of the present invention relate to a textile fiber, thread or yarn. The fiber, thread or yarn is generally for production into a fabric. Alternative aspects are described for achieving a cooling effect, energy harvesting, heating, energy generation, energy emission, and others.

Abstract: A formulation for a composite propellant including an oxidant suspended or embedded in a binder matrix, and the binder matrix having a cured or partially cured binder precursor including two or more functional groups.

Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.