Patents by Inventor Philip Lowe
Philip Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240083997Abstract: This invention relates to methods employing IL-1 beta-ligand/IL-1 receptor disrupting compounds, such as IL-1 beta antibodies or IL-1 receptor antibodies, in the treatment and/or prevention of auto-inflammatory syndromes in mammals, particularly humans.Type: ApplicationFiled: February 28, 2023Publication date: March 14, 2024Inventors: Hermann GRAM, Thomas JUNG, Philip LOWE, Trevor MUNDEL, Timothy WRIGHT
-
Publication number: 20230179678Abstract: Methods, systems, and computer programs are presented for lowering network latency for cloud-based services. Service-delivery edge locations allow customers to improve communication-providers public and private network connectivity for improved performance. One method includes operations for performing, by an edge server, a handshake to establish a communication session between a client and a main server, and for exchanging data between the client and the main server via the edge server. The handshake includes exchanging, by the edge server, communication initiation messages with the client, and validating, by the edge server, authentication credentials for the communication session based on the communication initiation messages.Type: ApplicationFiled: February 2, 2023Publication date: June 8, 2023Inventors: Alexander Philip Lowe, Madeleine Genevieve Muscari, Robert Charles Hagemann, III, Christer Jan Erik Fahlgren, Jeremy Andrew McEntire, Erik A. Jansson, Humberto Reyes, Evan Kyle Fossier, Jingming Niu
-
Patent number: 11601519Abstract: Methods, systems, and computer programs are presented for lowering network latency for cloud-based services. Service-delivery edge locations allow customers to improve communication-providers public and private network connectivity for improved performance. One method includes operations for performing, by an edge server, a handshake to establish a communication session between a client and a main server, and for exchanging data between the client and the main server via the edge server. The handshake includes exchanging, by the edge server, communication initiation messages with the client, and validating, by the edge server, authentication credentials for the communication session based on the communication initiation messages.Type: GrantFiled: August 12, 2020Date of Patent: March 7, 2023Assignee: Twilio Inc.Inventors: Alexander Philip Lowe, Madeleine Genevieve Muscari, Robert Charles Hagemann, III, Christer Jan Erik Fahlgren, Jeremy Andrew McEntire, Erik A. Jansson, Humberto Reyes, Evan Kyle Fossier, Jingming Niu
-
Publication number: 20210385292Abstract: Methods, systems, and computer programs are presented for lowering network latency for cloud-based services. Service-delivery edge locations allow customers to improve communication-providers public and private network connectivity for improved performance. One method includes operations for performing, by an edge server, a handshake to establish a communication session between a client and a main server, and for exchanging data between the client and the main server via the edge server. The handshake includes exchanging, by the edge server, communication initiation messages with the client, and validating, by the edge server, authentication credentials for the communication session based on the communication initiation messages.Type: ApplicationFiled: August 12, 2020Publication date: December 9, 2021Inventors: Alexander Philip Lowe, Madeleine Genevieve Muscari, Robert Charles Hagemann, III, Christer Jan Erik Fahlgren, Jeremy Andrew McEntire, Erik A. Jansson, Humberto Reyes, Evan Kyle Fossier, Jingming Niu
-
Publication number: 20210147533Abstract: This invention relates to methods employing IL-1 beta-ligand/IL-1 receptor disrupting compounds, such as IL-1 beta antibodies or IL-1 receptor antibodies, in the treatment and/or prevention of auto-inflammatory syndromes in mammals, particularly humans.Type: ApplicationFiled: June 19, 2020Publication date: May 20, 2021Inventors: Philip LOWE, Hermann GRAM, Thomas JUNG, Timothy WRIGHT, Trevor MUNDEL
-
Publication number: 20180201674Abstract: This invention relates to methods employing IL-1 beta-ligand/IL-1 receptor disrupting compounds, such as IL-1 beta antibodies or IL-1 receptor antibodies, in the treatment and/or prevention of auto-inflammatory syndromes in mammals, particularly humans.Type: ApplicationFiled: March 12, 2018Publication date: July 19, 2018Inventors: Philip Lowe, Hermann Gram, Thomas Jung, Timothy Wright, Trevor Mundel
-
Publication number: 20170218063Abstract: This invention relates to methods employing IL-1?-Ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules as described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.Type: ApplicationFiled: April 11, 2017Publication date: August 3, 2017Inventors: Philip Lowe, Hermann Gram, Thomas Jung, Timothy Wright, Trevor Mundel
-
Patent number: 9649377Abstract: This invention relates to methods employing IL-1?-ligand/IL-1 receptor disrupting compounds such as IL-1? antibodies or IL-1 receptor antibodies, in the treatment and/or prevention of Familial Mediterranean Fever (FMF), in mammals, particularly humans.Type: GrantFiled: July 28, 2015Date of Patent: May 16, 2017Assignee: Novartis AGInventors: Philip Lowe, Hermann Gram, Thomas Jung, Timothy Wright, Trevor Mundel
-
Publication number: 20150322148Abstract: This invention relates to methods employing IL-1?-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1? ligand-IL-1 receptor interaction, IL-1? antibodies or IL-1 receptor antibodies, e.g. IL-1? binding molecules as described herein, e.g. antibodies disclosed herein, e.g. IL-1? binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1? ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.Type: ApplicationFiled: July 28, 2015Publication date: November 12, 2015Applicant: Novartis AGInventors: Philip Lowe, Hermann Gram, Thomas Jung, Timothy Wright, Trevor Mundel
-
Patent number: 6499965Abstract: An air compressor system having a cast separator tank for use with an oil-flooded air compressor. The cast separator tank including an integrally cast air-end inlet opening which is mountable in face-to-face engagement with an air-end discharge opening of the compressor; an integrally cast first channel which extends between the air-end inlet opening and a separation chamber; an integrally cast second channel which communicates with a lower portion of the separation chamber and which extends along an outer portion of the cast separator tank; and an integrally cast lip which extends around an inner wall of the separation chamber. The integrally cast air-end inlet opening which is mounted to the discharge opening of the compressor, serves as a mounting foot, and supports the compressor on its discharge end. The compressor system further having a motor, such that the compressor, the motor and the cast separator tank are attached to from a single unit for ease of handling.Type: GrantFiled: February 2, 2001Date of Patent: December 31, 2002Assignee: Ingersoll-Rand CompanyInventors: Roger Cook, Jason J. Link, Elizabeth B. Warner, Norman Philip Lowe, James R. Dickey
-
Patent number: 6431210Abstract: An inlet valve for use in a gas compressor, the inlet valve including a piston movable within a housing chamber toward and away from a housing inlet and a valve disc movable with the piston, the valve disc including an aperture for selectively providing air flow from the housing inlet into the chamber, and a flexible member engageable with the valve disc to close the aperture. The inlet valve also includes a valve seat disposed near the housing inlet, and the piston is movable between a first position where the valve disc contacts the valve seat, and a second position where the valve disc is spaced from the valve seat. A spring biases the valve disc toward the valve seat.Type: GrantFiled: March 27, 2001Date of Patent: August 13, 2002Assignee: Ingersoll-Rand CompanyInventors: Norman Philip Lowe, Thomas E. Vincent
-
Publication number: 20020106287Abstract: An air compressor system having a cast separator tank for use with an oil-flooded air compressor. The cast separator tank including an integrally cast airend inlet opening which is mountable in face-to-face engagement with an airend discharge opening of the compressor; an integrally cast first channel which extends between the airend inlet opening and a separation chamber; an integrally cast second channel which communicates with a lower portion of the separation chamber and which extends along an outer portion of the cast separator tank; and an integrally cast lip which extends around an inner wall of the separation chamber. The compressor system further having a motor, such that the compressor, the motor and the cast separator tank are attached to form a single unit for ease of handling. The compressor system also has a plurality of mounting feet for attachment to an appropriate subbase.Type: ApplicationFiled: February 2, 2001Publication date: August 8, 2002Applicant: Ingersoll-Rand CompanyInventors: Roger Cook, Jason J. Link, Elizabeth B. Warner, Norman Philip Lowe, James R. Dickey
-
Patent number: 6409804Abstract: A separator tank assembly for use in a fluid compression system includes a separator element having a base, a support element mounted to the separator element, and a scavenge tube. The scavenge tube has a first end and a second end. The scavenge tube is fixed to the support element so that the first end of the scavenge tube is located at a predetermined position relative to the base of the separator element. The separator tank assembly also includes a tank housing having an outer flange at a top end thereof. The tank housing is dimensioned to receive the separator element. The separator tank assembly further includes a tank cover to attach to the outer flange of the tank housing. The tank cover has a cover orifice, and the separator tank assembly includes an adapter extending through the cover orifice. The adapter has a first section to connect to the second end of the scavenge tube and a second section to connect to a line component of the fluid compression system.Type: GrantFiled: September 29, 2000Date of Patent: June 25, 2002Assignee: Ingersoll-Rand CompanyInventors: Roger Cook, N. Philip Lowe
-
Patent number: 6004112Abstract: A compressor including a prime mover having an output element which supplies a motive force produced by the prime mover; a compression module having an input element; a tensioned belt connecting the prime mover output element and the compression module input element to transmit the motive force from the prime mover to the compression module, and a self-adjusting belt tensioning member for applying a substantially constant tensioning force to the belt to maintain substantially constant the predetermined required belt tension. The compressor also includes an anchor bracket connected to the compression module, and a locator plate connected to the anchor bracket, the locator plate being movable relative to the anchor bracket, the anchor bracket having a stop member for limiting movement of the locator plate.Type: GrantFiled: April 27, 1998Date of Patent: December 21, 1999Assignee: Ingersoll-Rand CompanyInventors: Roger Cook, Norman Philip Lowe