Patents by Inventor Philip M. Friden

Philip M. Friden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LEU3 gene sequence of S. cerevisiae and use in regulation of amino acid synthesis
    Patent number: 5032681
    Abstract: An analysis of LEU3, a leucine-specific regulatory locus encoding a factor for control of RNA levels of a group of leucine-specific genes, is provided.DNA sequence analysis of a clone of LEU3 shows that it contains an open reading frame of 886 amino acids. There are three regions of particular interest: a cluster of acidic amino acids that are located in the C-terminal half of the coding region, a region with a repeated cysteine motif, and a region of partial homology with MATalpha2. A LEU3-dependent DNA binding activity is demonstrated to interact with homologous portions of the 5'-region of LEU1 and LEU2.
    Type: Grant
    Filed: November 16, 1988
    Date of Patent: July 16, 1991
    Assignee: Massachusetts Institute of Technology
    Inventors: Philip M. Friden, Paul R. Schimmel
  • LEU3 gene sequence of S. cerevisiae and use in regulation of amino acid synthesis
    Patent number: 4870159
    Abstract: An analysis of LEU3, a leucine-specific regulatory locus encoding a factor for control of RNA levels of a group of leucine-specific genes, is provided.DNA sequence analysis of a clone of LEU3 shows that it contains an open reading frame of 886 amino acids. There are three regions of particular interest: a cluster of acidic amino acids that are located in the C-terminal half of the coding region, a region with a repeated cysteine motif, and a region of partial homology with MATalpha2. A LEU3-dependent DNA binding activity is demonstrated to interact with homologous portions of the 5'-region of LEU1 and LEU2.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: September 26, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Philip M. Friden, Paul R. Schimmel