Patents by Inventor Philip Mallinder

Philip Mallinder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Publication number: 20210371513
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.
    Type: Application
    Filed: April 9, 2021
    Publication date: December 2, 2021
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • Compounds
    Publication number: 20200079845
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.
    Type: Application
    Filed: March 21, 2019
    Publication date: March 12, 2020
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • Compounds
    Publication number: 20180162936
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6 ) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.
    Type: Application
    Filed: June 30, 2017
    Publication date: June 14, 2018
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • Compounds
    Publication number: 20150197568
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.
    Type: Application
    Filed: April 1, 2015
    Publication date: July 16, 2015
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • Compounds
    Patent number: 9005620
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralize its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumors associated with IL-6.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: April 14, 2015
    Assignee: MedImmune Limited
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • Compounds
    Publication number: 20120301462
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.
    Type: Application
    Filed: May 25, 2012
    Publication date: November 29, 2012
    Applicant: MedImmune Limited
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • Anti-human IL-6 antibodies
    Patent number: 8198414
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralize its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumors associated with IL-6.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: June 12, 2012
    Assignee: MedImmune Limited
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder
  • ANTI-PAI-1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20120114652
    Abstract: Provided are anti-PAI-1 antibodies or antibody fragments and methods of using them.
    Type: Application
    Filed: May 2, 2011
    Publication date: May 10, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: John Elvin, Patrick Dufner, Philip Newton, Philip Mallinder
  • Antibodies specific for the complex of interleukin-6 and the interleukin-6 receptor
    Patent number: 8153128
    Abstract: Binding members, especially antibody molecules that bind the IL-6:IL-6Ra complex formed by IL-6 and IL-6Ra, and do not bind either IL-6 or IL-6Ra alone. The binding members may have greater specificity for inhibiting pathological effects of IL-6 rather than beneficial effects of IL-6, as compared with binding members that bind IL-6 or IL-6Ra outside the IL-6:IL-6Ra complex.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: April 10, 2012
    Assignee: MedImmune Limited
    Inventors: Keith Bowers, Steven Godfrey Lane, Philip Mallinder, Isabelle Veronique Yolande Ossona De Mendez
  • Antibodies Specific For The Complex Of Interleukin-6 And The Interleukin-6 Receptor
    Publication number: 20100098709
    Abstract: Binding members, especially antibody molecules that bind the IL-6:IL-6Ra complex formed by IL-6 and IL-6Ra, and do not bind either IL-6 or IL-6Ra alone. The binding members may have greater specificity for inhibiting pathological effects of IL-6 rather than beneficial effects of IL-6, as compared with binding members that bind IL-6 or IL-6Ra outside the IL-6:IL-6Ra complex.
    Type: Application
    Filed: November 28, 2007
    Publication date: April 22, 2010
    Applicants: AstraZeneca AB, MedImmune Limited
    Inventors: Keith Cyril Bowers, Steven Godfrey Lane, Philip Mallinder, Isabelle Veronique Yolande Ossona De Mendez
  • Assays for Allosteric Modulators of G-Protein Coupled Receptors (GPCRs)
    Publication number: 20090305321
    Abstract: The present invention relates to G protein-coupled receptors (GPCRs) and allosteric modulators thereof. More specifically, the invention relates to allosteric modulators of GPCRs that interact at an intracellular binding site. It also relates to methods for designing or identifying small molecule allosteric modulators, including assays (such as competitive binding assays) and methods employing a homology model for the GPCR intracellular site.
    Type: Application
    Filed: March 22, 2006
    Publication date: December 10, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Caroline Grahames, Philip Mallinder, Fraser McIntosh, Nicholas Tomkinson, Tracey Wright
  • COMPOUNDS
    Publication number: 20080188401
    Abstract: Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralise its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumours associated with IL-6.
    Type: Application
    Filed: November 30, 2007
    Publication date: August 7, 2008
    Inventors: Simon Charles Cruwys, Steven Godfrey Lane, Philip Mallinder