Abstract: A method of operating an EWOD device to employs a magnetic field to separate magnetically responsive particles from a polar liquid droplet. The method includes the steps of dispensing a liquid droplet onto an element array of the EWOD device, wherein the liquid droplet includes magnetically responsive particles; performing an electrowetting operation to move the liquid droplet along the element array to a location relative to a magnet element in proximity to that location of the EWOD device; operating the magnet element to apply a magnetic field to the liquid droplet, wherein at least a portion of the magnetically responsive particles aggregate within the liquid droplet in response to the magnetic field; and separating the aggregated magnetically responsive particles from the liquid droplet with the magnetic field, wherein the aggregated magnetically responsive particles move in response to the magnetic field to a location on the element array in proximity to the magnet element.

Abstract: A microfluidic control system for controlling an EWOD device has an enhanced thermal control system for generating a temperature profile within an EWOD device that is inserted into the microfluidic control system. The microfluidic control system includes a housing that defines an aperture for receiving an EWOD device; an active heating component located within the housing at a base of the aperture; and a lid attached to the housing that is moveable between a closed position and an open position, the lid including a thermal control component. When the lid is in the closed position, the thermal control component is positioned at the aperture and aligned oppositely from the active heating component. The active heating component may include a plurality of independently controllable individual heating elements, and the thermal control component may include a respective plurality of individual thermal control elements.

Abstract: An EWOD device and a related method of performing a digital biological assay are described that employs two volume measurements for enhanced assay determination. The method includes partitioning a sample reservoir and measuring the volume of each partition; initiating a biological assay wherein the biological assay includes measuring a partition property and a volume of each partition in real time as part of determining a concentration of the product substance in each partition based on the measured partition property and volume; and categorizing the partitions by a number of biological entities contained in each partition from which the number of biological entities may be calculated, which in turn may be used to calculate the total number of biological entities or concentration in the sample reservoir. The method further may include an enhanced partitioning process that minimizes variation in the volume of the partitions.

Abstract: A method of digital quantification of a species in an EWOD device includes inputting a sample volume and a diluent volume into the EWOD device; performing an electrowetting operation to generate a first sample droplet from the sample volume; performing an amplification process on the first sample droplet and measuring a turn-on value for the sample droplet; comparing the measured turn-on value to a target turn-on value for digital quantification; calculating a dilution factor based on the comparison of the measured and target turn-on values; performing an electrowetting operation to extract a second sample droplet from the sample volume; performing an electrowetting operation to dilute the second sample droplet with the diluent volume by the dilution factor to form a diluted second sample droplet; and performing a digital quantification on the diluted second sample droplet to quantify an initial concentration of the species in the sample volume.

Abstract: A microfluidic control system for controlling an EWOD device has an enhanced thermal control system for generating a temperature profile within an EWOD device that is inserted into the microfluidic control system. The microfluidic control system includes a housing that defines an aperture for receiving an EWOD device; an active heating component located within the housing at a base of the aperture; and a lid attached to the housing that is moveable between a closed position and an open position, the lid including a thermal control component. When the lid is in the closed position, the thermal control component is positioned at the aperture and aligned oppositely from the active heating component. The active heating component may include a plurality of independently controllable individual heating elements, and the thermal control component may include a respective plurality of individual thermal control elements.

Abstract: An active matrix electro-wetting on dielectric (AM-EWOD) device has an optically black array element structure to enhance optical detection of constituents within a liquid droplet. The AM-EWOD device includes a thin film transistor (TFT) substrate assembly having a hydrophobic layer; thin film electronics having a plurality of array elements arranged in an array of rows and columns, each of the array elements including an array element electrode and a TFT device; and an optically black material disposed between a plane of the TFT device and the hydrophobic layer. The TFT substrate assembly further includes a planarization structure that includes a component having the optically black material. The planarization structure has a planarization component disposed between the TFT device and the array element electrode, and an ionic barrier disposed between the array element electrode and the hydrophobic coating. The planarization component or the ionic barrier includes the optically black material.

Abstract: A microfluidic system is configured for enhanced temperature control by combining spatial and temporal temperature control. The microfluidic system includes an electro-wetting on dielectric (EWOD) device comprising an element array configured to receive one or more liquid droplets, the element array comprising a plurality of individual array elements; a control system configured to control actuation voltages applied to the element array to perform manipulation operations of the liquid droplets; and a plurality of thermal control elements located at different spatial locations along the EWOD device, at least one of the thermal control elements being variable in temperature with respect to time. The control system includes a thermal control unit configured to control temperatures of the thermal control elements to generate a plurality of thermal zones located at different spatial locations along the EWOD device, at least one of the thermal zones being variable in temperature with respect to time.

Abstract: An electrowetting on dielectric (EWOD) device and a related method of performing a digital biological assay in an EWOD device are described.

Abstract: An active matrix electro-wetting on dielectric (AM-EWOD) device has an optically black array element structure to enhance optical detection of constituents within a liquid droplet. The AM-EWOD device includes a thin film transistor (TFT) substrate assembly having a hydrophobic layer; thin film electronics having a plurality of array elements arranged in an array of rows and columns, each of the array elements including an array element electrode and a TFT device; and an optically black material disposed between a plane of the TFT device and the hydrophobic layer. The TFT substrate assembly further includes a planarization structure that includes a component having the optically black material. The planarization structure has a planarization component disposed between the TFT device and the array element electrode, and an ionic barrier disposed between the array element electrode and the hydrophobic coating. The planarization component or the ionic barrier includes the optically black material.

Abstract: A method of performing a digital quantification of a species in an electrowetting on dielectric (EWOD) device comprising the steps of: inputting a sample volume into the EWOD device; inputting a diluent volume into the EWOD device; performing an electrowetting operation to generate a first sample droplet from the sample volume; performing an amplification process on the first sample droplet within the EWOD device; measuring a turn-on value for the sample droplet; comparing the measured turn-on value of the sample droplet to a target turn-on value for digital quantification; calculating a dilution factor based on the comparison of the measured turn-on value of the sample droplet to the target turn-on value; performing an electrowetting operation to extract a second sample droplet from the sample volume; performing an electrowetting operation to dilute the second sample droplet with the diluent volume in accordance with the dilution factor to form a diluted second sample droplet; and performing a digital quanti

Abstract: A microfluidic system is configured for enhanced temperature control by combining spatial and temporal temperature control. The microfluidic system includes an electro-wetting on dielectric (EWOD) device comprising an element array configured to receive one or more liquid droplets, the element array comprising a plurality of individual array elements; a control system configured to control actuation voltages applied to the element array to perform manipulation operations of the liquid droplets; and a plurality of thermal control elements located at different spatial locations along the EWOD device, at least one of the thermal control elements being variable in temperature with respect to time. The control system includes a thermal control unit configured to control temperatures of the thermal control elements to generate a plurality of thermal zones located at different spatial locations along the EWOD device, at least one of the thermal zones being variable in temperature with respect to time.

Abstract: A water purifier includes a first crystallization chamber and a second crystallization chamber that each receives a supply of input water; wherein each of the first and second crystallization chambers is a freeze/thaw chamber in which water is alternately frozen and thawed. A refrigerant circuit alternately supplies cold refrigerant to freeze the input water in one of the crystallization chambers, and supplies heated refrigerant to the other of the crystallization chambers to thaw the purified water. The first and second crystallization chambers operate concurrently and out-of-phase whereby heat recovered from freezing in one of the crystallization chambers is transferred by the refrigerant circuit for use in thawing in the other of the crystallization chambers.

Abstract: An apparatus extracts water from the air using a single circuit of gas containing a compressor, a cooling element, a heat exchanger and an ion source, where a single stream of air is used to provide water and to pre-cool the inlet air.

Abstract: A composite material comprises magnetic particles dispersed in electrically insulating material. The magnetic particles have an aspect ratio greater than 1 (preferably greater than 10) and a concentration sufficiently high to produce negative permeability. The magnetic particles may be magnetic flakes of reduced carbonyl iron of average diameter 50 ?m, average thickness 1 ?m and aspect ratio 50, the magnetic flakes being at least 25% by volume of the composite material. The magnetic flakes may be aligned to produce enhanced permeability. The electrically insulating material may be paraffin wax, particulate PTFE, or another polymer. To control permittivity, the composite material may include an electrically conducting component such as graphite or conductive coatings upon the magnetic flakes.

Abstract: This invention relates to the field of an electromagnetic (EM) field shielding paint compositions, in particular, those capable of providing substantially non metallic finish. The paint composition finds particular use in attenuating EM signals that may be used to carry data between communication devices, especially mobile phone and wi-fi devices. EM field shielding paints are typically available in jet-black or bright metallic finishes and usually possess limited scratch & abrasion resistance. The paint composition provides a one-pot solution to furnish a composition which has the visual appearance of a domestic type paint i.e. one with a non-metallic finish, with the ability to shield electromagnetic radiation. The composition comprises a supported metallic flake and a pigment, which have been provided in a narrowly defined range to furnish a desirable non-metallic appearance and possess electromagnetic shielding properties.

Abstract: A core-shell nanoparticle which includes a core formed of a transparent material and a shell including vanadium dioxide (VO2) doped to have a semiconductor-metal phase transition within a range of 10° C. to 40° C. A ratio of thicknesses of the core to the shell is in a range of 1:1 to 50:1.

Abstract: A composite materil comprises magnetic particles dispersed in electrically insulating material. The magnetic particles have an aspect ratio greater than 1 (preferably greater than 10) and a concentration sufficiently high to produce negative permeability. The magnetic particles may be magnetic flakes of reduced carbonyl iron of average diameter 50 ?m, average thickness 1 ?m and aspect ratio 50, the magnetic flakes being at least 25% by volume of the composite material. The magnetic flakes may be aligned to produce enhanced permeability. The electrically insulating material may be paraffin wax, particulate PTFE, or another polymer. To control permittivity, the composite material may include an electrically conducting component such as graphite or conductive coatings upon the magnetic flakes.