Patents by Inventor Philip Oh

Philip Oh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue-specific imaging and therapeutic agents targeting proteins expressed on lung endothelial cell surface
    Patent number: 8815235
    Abstract: Methods of delivering an agent in a tissue-specific manner, particularly lung tissue, by targeting a protein expressed on the endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating pathologies, as well as for diagnostics.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: August 26, 2014
    Inventors: Jan E. Schnitzer, Philip Oh
  • Vascular targets for detecting, imaging and treating neoplasia or neovasculature
    Patent number: 8715675
    Abstract: Methods of delivering an agent in a tissue-specific manner, by targeting annexin A1, a derivative of annexin A1, or a binding partner of annexin A1, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy. Antibodies to annexin A1 are also described, as are methods screening for agents altering annexin A1 activity.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: May 6, 2014
    Inventors: Jan E. Schnitzer, Philip Oh
  • ECTOPIC, ORTHOTOPIC MODEL FOR REVASCULARIZATION AND TUMOR ASSESSMENT
    Publication number: 20110173709
    Abstract: Improved vascularization and tumor models, comprising a test animal having a dorsal skin window chamber, and an exogenous tissue sample implanted ectopically in the skin within the window chamber, are described, as are methods of using the models.
    Type: Application
    Filed: February 29, 2008
    Publication date: July 14, 2011
    Inventors: Jan E. Schnitzer, Philip Oh, Per Borgstrom
  • VASCULAR TARGETS FOR DETECTING, IMAGING AND TREATING NEOPLASIA OR NEOVASCULATURE
    Publication number: 20110044893
    Abstract: Methods of delivering an agent in a tissue-specific manner, by targeting annexin A1, a derivative of annexin A1, or a binding partner of annexin A1, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy. Antibodies to annexin A1 are also described, as are methods screening for agents altering annexin A1 activity.
    Type: Application
    Filed: April 23, 2010
    Publication date: February 24, 2011
    Inventors: Jan E. Schnitzer, Philip Oh
  • Imaging and therapeutic agents targeting proteins expressed on endothelial cell surface
    Publication number: 20060024232
    Abstract: Methods of delivering an agent in a tissue-specific manner, by targeting proteins expressed on endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy.
    Type: Application
    Filed: June 2, 2005
    Publication date: February 2, 2006
    Applicant: Sidney Kimmel Cancer Center
    Inventors: Jan Schnitzer, Philip Oh
  • Tissue-specific imaging and therapeutic agents targeting proteins expressed on lung endothelial cell surface
    Publication number: 20060024231
    Abstract: Methods of delivering an agent in a tissue-specific manner, particularly lung tissue, by targeting a protein expressed on the endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating pathologies, as well as for diagnostics.
    Type: Application
    Filed: June 2, 2005
    Publication date: February 2, 2006
    Applicant: Sidney Kimmel Cancer Center
    Inventors: Jan Schnitzer, Philip Oh
  • Vascular targets for detecting, imaging and treating neoplasia or neovasculature
    Publication number: 20060024315
    Abstract: Methods of delivering an agent in a tissue-specific manner, by targeting annexin A1, a derivative of annexin A1, or a binding partner of annexin A1, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy. Antibodies to annexin A1 are also described, as are methods screening for agents altering annexin A1 activity.
    Type: Application
    Filed: June 2, 2005
    Publication date: February 2, 2006
    Applicant: Sidney Kimmel Cancer Center
    Inventors: Jan Schnitzer, Philip Oh
  • Immunoisolation of caveolae
    Patent number: 6737516
    Abstract: Method of producing purified caveolae are described, in which a sample of interest comprising plasma membranes is subjected to an immunoisolation method in which the sample of interest is incubated with an antibody that is specific for caveolin and which binds to caveolin in its native (oligomeric) state, preferably for a brief time period, and caveolae that are bound to the antibody are separated from other materials in the sample of interest. Purified caveolae produced by the methods, and uses for the purified caveolae, are also described.
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: May 18, 2004
    Inventors: Jan E. Schnitzer, Philip Oh