Patents by Inventor Philip P. Grous

Philip P. Grous has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diphenylamine cardiovascular agents, compositions and use
    Patent number: 5185362
    Abstract: Propylamines of the formula (I): ##STR1## and isomers thereof, particularly those enantiomers and racemates relative to the chiral carbon indicated by an asterisk (*). The propylamines can be used for the treatment of hypertension or angina in humans. A is pyrrolidine, piperidine or morpholine and B is an aromatic heterocycle, aromatic carbocycle or saturated carbocycle.
    Type: Grant
    Filed: July 8, 1991
    Date of Patent: February 9, 1993
    Assignee: McNeilab, Inc.
    Inventors: Philip P. Grous, Richard J. Mohrbacher
  • 3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents
    Patent number: 4888335
    Abstract: Propylamines of the formula (I): ##STR1## and isomers thereof, particularly those enantiomers and racemates relative to the chiral carbon indicated by an asterisk (*). The propylamines can be used for the treatment of hypertension or angina in humans. A is pyrrolidine, piperidine or morpholine, Z is alkylene, alkenylene, oxygen or a sulfur atom and W is an oxygen or a sulfur atom.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: December 19, 1989
    Assignee: McNeilab, Inc.
    Inventors: Richard J. Mohrbacher, Philip P. Grous
  • 3-alkoxy-2-aminopropyamines, cardiovascular compositions and use
    Patent number: 4758563
    Abstract: Propylamines of the formula (I): ##STR1## and isomers thereof, particularly those enantiomers and racemates relative to the chiral carbon indicated by an asterisk (*). The propylamines can be used for the treatment of hypertension or angina in humans. A is pyrrolidine, piperidine or morpholine and B is an aromatic heterocycle, aromatic carbocycle or saturated carbocycle.
    Type: Grant
    Filed: November 9, 1987
    Date of Patent: July 19, 1988
    Assignee: McNeilab, Inc.
    Inventors: Philip P. Grous, Richard J. Mohrbacher
  • 3-alkoxy-2-aminopropylamines compositions and use as cardiovascular agents
    Patent number: 4727072
    Abstract: Propylamines of the formula (I): ##STR1## and isomers thereof, particularly those enantiomers and racemates relative to the chiral carbon indicated by an asterisk (*). The propylamines can be used for the treatment of hypertension or angina in humans. A is pyrrolidine, piperidine or morpholine and B is an aromatic heterocycle, aromatic carbocycle or saturated carbocycle.
    Type: Grant
    Filed: February 12, 1986
    Date of Patent: February 23, 1988
    Assignee: McNeilab, Inc.
    Inventors: Philip P. Grous, Richard J. Mohrbacher
  • Intermediates for 2-aminobenzodiazepine-5-ones
    Patent number: 4031079
    Abstract: Compounds of the class of 2-amino-3,4-dihydro-4-loweralkyl-5H-1,4-benzodiazepine-5-ones useful as CNS depressants and hypotensive agents.
    Type: Grant
    Filed: June 23, 1976
    Date of Patent: June 21, 1977
    Assignee: McNeil Laboratories, Incorporated
    Inventors: Richard J. Mohrbacher, Philip P. Grous
  • 2-Aminobenzodiazepine-5-ones
    Patent number: 4022767
    Abstract: Compounds of the class of 2-amino-3,4-dihydro-4-loweralkyl-5H-1,4-benzodiazepine-5-ones useful as CNS depressants and hypotensive agents.
    Type: Grant
    Filed: June 23, 1976
    Date of Patent: May 10, 1977
    Assignee: McNeil Laboratories, Incorporated
    Inventors: Richard J. Mohrbacher, Philip P. Grous
  • Intermediates for 2-aminobenzodiazepine-5-ones
    Patent number: 4020055
    Abstract: Compounds of the class of 2-amino-3,4-dihydro-4-loweralkyl-5H-1,4-benzodiazepine-5-ones useful as CNS depressants and hypotensive agents.
    Type: Grant
    Filed: June 23, 1976
    Date of Patent: April 26, 1977
    Assignee: McNeil Laboratories, Incorporated
    Inventors: Richard J. Mohrbacher, Philip P. Grous
  • 2-Aminobenzodiazepine-5-ones
    Patent number: 4002610
    Abstract: Compounds of the class of 2-amino-3,4-dihydro-4-loweralkyl-5H-1,4-benzodiazepine-5-ones useful as CNS depressants and hypotensive agents.
    Type: Grant
    Filed: September 22, 1975
    Date of Patent: January 11, 1977
    Assignee: McNeil Laboratories, Incorporated
    Inventors: Richard J. Mohrbacher, Philip P. Grous