Patents by Inventor Philip P. Wang

Philip P. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOASSAYS EXHIBITING REDUCED CROSS-REACTIVITY WITH HYDROPHOBIC DRUG ANALYTE METABOLITES
    Publication number: 20080311676
    Abstract: The present disclosure provides among other things immunoassays exhibiting reduced cross-reactivity with analyte metabolites. Additionally, the present disclosure provides diagnostic immunoassays to determine the concentration or level in a test sample of a hydrophobic drug that metabolizes in vivo or in vitro to form cross-reacting metabolites wherein cross-reactivity with such metabolites of the drug analyte is reduced. In particular, the disclosure provides such immunoassays where the hydrophobic drug is an immunosuppressant drug such as cyclosporine A.
    Type: Application
    Filed: May 23, 2008
    Publication date: December 18, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: Elaine M. Brate, David M. Finley, Shelley R. Holets-McCormack, David P. Pacenti, Ryan E. Piktel, Michelle Shields, Thomas G. Spring, Philip P. Wang
  • Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
    Patent number: 5427960
    Abstract: The present invention is directed to a fluorescence polarization immunoassay for cyclosporin A and metabolites thereof. The present invention also relates to novel cyclosporin A derivative compounds useful in fluorescence polarization techniques. Included among the novel compounds are cyclosporin A derivatives where the amino acid in the first position is altered. The cyclosporin A derivatives are useful in forming immunogens for raising antibodies specific to cyclosporin A and metabolites thereof.
    Type: Grant
    Filed: October 5, 1994
    Date of Patent: June 27, 1995
    Assignee: Abbott Laboratories
    Inventors: Nai-Yi Wang, Philip P. Wang, Marjorie A. Morrison
  • Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
    Patent number: 5239057
    Abstract: The present invention is directed to a fluorescence polarization immunoassay for cyclosporin A and metabolites thereof. The present invention also relates to novel cyclosporin A derivative compounds useful in fluorescence polarization techniques. Included among the novel compounds are cyclosporin A derivatives where the amino acid in the first position is altered. The cyclosporin A derivatives are useful in forming immunogens for raising antibodies specific to cyclosporin A and metabolites thereof.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: August 24, 1993
    Assignee: Abbott Laboratories
    Inventors: Nai-Yi Wang, Philip P. Wang, Marjorie A. Morrison
  • Precipitation of interfering proteins in fluorescence polarization immunoassay for digoxin
    Patent number: 4734378
    Abstract: Interfering proteins are precipitated and digoxin extracted in a fluorescence polarization immunoassay for digoxin with a protein precipitating reagent. The reagent contains about 3 to 4% 5-sulfosalicyclic acid in an aqueous solution including about 40 to 60% of a straight or branch chained organic alcohol having from 1 to 4 carbon atoms.
    Type: Grant
    Filed: June 26, 1985
    Date of Patent: March 29, 1988
    Assignee: Abbott Laboratories
    Inventors: Philip P. Wang, Gloria J. Hockerman