Patents by Inventor Philip Paik
Philip Paik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240408597Abstract: An instrument includes a reagent management system. The reagent management system includes a plurality of reagent wells, each reagent well operable to contain a reagent of a plurality of reagents positioned therein. The reagent management system is operable to select a flow of reagent from one of the plurality of reagents. A flexible connection includes a laminate stack and includes a first flexible channel in fluid communication with the reagent management system. The first flexible channel is operable to route the flow of reagent therethrough. A flow cell includes a flow channel in fluid communication with the first flexible channel. The flow channel is operable to route the flow of reagent over analytes positioned in the flow channel. The flexible connection enables the flow cell to be moved by the instrument relative to a fixed reference point in the instrument.Type: ApplicationFiled: August 19, 2024Publication date: December 12, 2024Applicant: Illumina, Inc.Inventors: Cyril DELATTRE, Minsoung RHEE, Jeffrey LIU, Wesley COX-MURANAMI, Paul CRIVELLI, Jennifer FOLEY, Darren SEGALE, Jay TAYLOR, Matthew HAGE, Philip PAIK, Erik ALLEGOREN, David HERTZOG, Alex MOROZ-SMIETANA, Xiaoxiao MA, Tsukasa TAKAHASHI, Brandon WESTERBERG
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Patent number: 12064761Abstract: An instrument includes a reagent management system. The reagent management system includes a plurality of reagent wells, each reagent well operable to contain a reagent of a plurality of reagents positioned therein. The reagent management system is operable to select a flow of reagent from one of the plurality of reagents. A flexible connection includes a laminate stack and includes a first flexible channel in fluid communication with the reagent management system. The first flexible channel is operable to route the flow of reagent therethrough. A flow cell includes a flow channel in fluid communication with the first flexible channel. The flow channel is operable to route the flow of reagent over analytes positioned in the flow channel. The flexible connection enables the flow cell to be moved by the instrument relative to a fixed reference point in the instrument.Type: GrantFiled: May 2, 2019Date of Patent: August 20, 2024Assignee: Illumina, Inc.Inventors: Cyril Delattre, Minsoung Rhee, Jeffrey Liu, Wesley Cox-Muranami, Paul Crivelli, Jennifer Foley, Darren Segale, Jay Taylor, Matthew Hage, Philip Paik, Erik Allegoren, David Hertzog, Alex Moroz-Smietana, Xiaoxiao Ma, Tsukasa Takahashi, Brandon Westerberg
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Patent number: 11174513Abstract: A stack of fluidics layers of a microfluidic cartridge for sequencing nucleic acid molecules includes a sequencing chamber layer having a sequencing chamber area configured for carrying out clustering and sequencing reactions, and a sequencing chamber bottom layer disposed under the sequencing chamber layer. The sequencing chamber bottom layer has an opening configured to hold an image sensor with the image sensor having an active area disposed under the sequencing chamber area. The sequencing chamber area spans substantially all of the active area of the image sensor. The stack of fluidics layers includes a flexible printed circuit board (PCB) layer under the sequencing chamber bottom layer, and a fluidics channels layer disposed under the flexible PCB layer. The fluidics channels layer includes fluidics channels that are configured to deliver reactants to the sequencing chamber area. The fluidics channels do not substantially overlap with the active area of the image sensor.Type: GrantFiled: May 7, 2019Date of Patent: November 16, 2021Assignee: Illumina, Inc.Inventors: Poorya Sabounchi, Behnam Javanmardi, Tarun Khurana, Philip Paik, Yan-You Lin
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Patent number: 10767219Abstract: The disclosed embodiments concern microfluidic cartridges for detecting biological reactions. In some embodiments, the microfluidic cartridges are configured to perform sequencing operations on a nucleic acid sample. In one aspect, a microfluidic cartridge includes a stack of fluidics layers defining channels and valves for processing the nucleic acid sample to be sequenced, and a solid state CMOS biosensor integrated in the stack. The biosensor has an active area configured to detect signals of biological reactions, wherein substantially all of the active area is available for reagent delivery and illumination during operation. In another aspect, a microfluidic cartridge includes: (a) a flow cell including a reaction site area encompassing one or more reaction sites; (b) fluidics channels for delivering reactants to and/or removing reactants from the reaction site area; (c) a biosensor having an active area configured to detect signals of biological reactions in the reaction site area.Type: GrantFiled: March 11, 2015Date of Patent: September 8, 2020Assignee: ILLUMINA, INC.Inventors: Poorya Sabounchi, Behnam Javanmardi, Tarun Khurana, Philip Paik, Yan-You Lin
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Publication number: 20190351413Abstract: An instrument includes a reagent management system. The reagent management system includes a plurality of reagent wells, each reagent well operable to contain a reagent of a plurality of reagents positioned therein. The reagent management system is operable to select a flow of reagent from one of the plurality of reagents. A flexible connection includes a laminate stack and includes a first flexible channel in fluid communication with the reagent management system. The first flexible channel is operable to route the flow of reagent therethrough. A flow cell includes a flow channel in fluid communication with the first flexible channel. The flow channel is operable to route the flow of reagent over analytes positioned in the flow channel. The flexible connection enables the flow cell to be moved by the instrument relative to a fixed reference point in the instrument.Type: ApplicationFiled: May 2, 2019Publication date: November 21, 2019Applicant: Illumina, Inc.Inventors: Cyril DELATTRE, Minsoung RHEE, Jeffrey LIU, Wesley COX-MURANAMI, Paul CRIVELLI, Jennifer FOLEY, Darren SEGALE, Jay TAYLOR, Matthew HAGE, Philip PAIK, Erik ALLEGOREN, David HERTZOG, Alex MOROZ-SMIETANA, Xiaoxiao MA, Tsukasa TAKAHASHI, Brandon WESTERBERG
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Publication number: 20190264276Abstract: A stack of fluidics layers of a microfluidic cartridge for sequencing nucleic acid molecules includes a sequencing chamber layer having a sequencing chamber area configured for carrying out clustering and sequencing reactions, and a sequencing chamber bottom layer disposed under the sequencing chamber layer. The sequencing chamber bottom layer has an opening configured to hold an image sensor with the image sensor having an active area disposed under the sequencing chamber area. The sequencing chamber area spans substantially all of the active area of the image sensor. The stack of fluidics layers includes a flexible printed circuit board (PCB) layer under the sequencing chamber bottom layer, and a fluidics channels layer disposed under the flexible PCB layer. The fluidics channels layer includes fluidics channels that are configured to deliver reactants to the sequencing chamber area. The fluidics channels do not substantially overlap with the active area of the image sensor.Type: ApplicationFiled: May 7, 2019Publication date: August 29, 2019Inventors: Poorya Sabounchi, Behnam Javanmardi, Tarun Khurana, Philip Paik, Yan-You Lin
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Publication number: 20170016060Abstract: The disclosed embodiments concern microfluidic cartridges for detecting biological reactions. In some embodiments, the microfluidic cartridges are configured to perform sequencing operations on a nucleic acid sample. In one aspect, a microfluidic cartridge includes a stack of fluidics layers defining channels and valves for processing the nucleic acid sample to be sequenced, and a solid state CMOS biosensor integrated in the stack. The biosensor has an active area configured to detect signals of biological reactions, wherein substantially all of the active area is available for reagent delivery and illumination during operation. In another aspect, a microfluidic cartridge includes: (a) a flow cell including a reaction site area encompassing one or more reaction sites; (b) fluidics channels for delivering reactants to and/or removing reactants from the reaction site area; (c) a biosensor having an active area configured to detect signals of biological reactions in the reaction site area.Type: ApplicationFiled: March 11, 2015Publication date: January 19, 2017Inventors: Poorya Sabounchi, Behnam Javanmardi, Tarun Khurana, Philip Paik, Yan-You Lin
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Patent number: D895146Type: GrantFiled: November 25, 2019Date of Patent: September 1, 2020Assignee: Illumina, Inc.Inventors: James Osmus, Erik Allegoren, James Blake, Philip Paik, Jay Taylor, Jack Godfrey-Wood
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Patent number: D913518Type: GrantFiled: November 25, 2019Date of Patent: March 16, 2021Assignee: Illumina, Inc.Inventors: James Osmus, Erik Allegoren, James Blake, Philip Paik, Jay Taylor
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Patent number: D942033Type: GrantFiled: November 25, 2019Date of Patent: January 25, 2022Assignee: Illumina, Inc.Inventors: James Osmus, Erik Allegoren, James Blake, Philip Paik, Jay Taylor, Jack Godfrey-Wood
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Patent number: D942034Type: GrantFiled: August 5, 2020Date of Patent: January 25, 2022Assignee: Illumina, Inc.Inventors: James Osmus, Erik Allegoren, James Blake, Philip Paik, Jay Taylor, Jack Godfrey Wood
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Patent number: D949432Type: GrantFiled: November 25, 2019Date of Patent: April 19, 2022Assignee: Illumina, Inc.Inventors: James Osmus, Erik Allegoren, James Blake, Philip Paik, Jay Taylor, Jack Godfrey-Wood
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Patent number: D953573Type: GrantFiled: November 25, 2019Date of Patent: May 31, 2022Assignee: ILLUMINA, INC.Inventors: Jay Taylor, James Osmus, Philip Paik, Jack Godfrey Wood, Carlos Dominguez
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Patent number: D953574Type: GrantFiled: November 25, 2019Date of Patent: May 31, 2022Assignee: Illumina, Inc.Inventors: Jay Taylor, James Osmus, Philip Paik, Jack Godfrey Wood, Carlos Dominguez, Max Pollock
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Patent number: D953575Type: GrantFiled: November 25, 2019Date of Patent: May 31, 2022Assignee: Illumina, Inc.Inventors: Jay Taylor, James Osmus, Philip Paik, Jack Godfrey-Wood, Carlos Dominguez
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Patent number: D952892Type: GrantFiled: November 25, 2019Date of Patent: May 24, 2022Assignee: Illumina, Inc.Inventors: James Osmus, Erik Allegoren, James Blake, Philip Paik, Jay Taylor, Jack Godfrey-Wood, Carlos Dominguez
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Patent number: D962467Type: GrantFiled: November 25, 2019Date of Patent: August 30, 2022Assignee: Illumina, Inc.Inventors: Jay Taylor, Bradley Drews, James Osmus, Philip Paik, Tsukasa Takahashi, Brandon Westerberg, Jack Godfrey Wood, Carlos Dominguez
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Patent number: D999425Type: GrantFiled: November 25, 2019Date of Patent: September 19, 2023Assignee: Illumina, Inc.Inventors: Jay Taylor, James Osmus, Philip Paik, Jack Godfrey Wood, Max Pollock
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Patent number: D1003452Type: GrantFiled: July 27, 2022Date of Patent: October 31, 2023Assignee: Illumina, Inc.Inventors: Jay Taylor, Bradley Drews, James Osmus, Philip Paik, Tsukasa Takahashi, Brandon Westerberg, Jack Godfrey Wood, Carlos Dominguez
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Patent number: D1012313Type: GrantFiled: May 31, 2022Date of Patent: January 23, 2024Assignee: Illumina, Inc.Inventors: Jay Taylor, James Osmus, Philip Paik, Jack Godfrey Wood, Carlos Dominguez