Patents by Inventor Philip Paul Chamberlain

Philip Paul Chamberlain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for measuring small molecule affinity to cereblon
    Patent number: 11644461
    Abstract: A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: May 9, 2023
    Assignee: CELGENE CORPORATION
    Inventors: Philip Paul Chamberlain, Mary Matyskiela, Godrej Khambatta
  • METHODS FOR MEASURING SMALL MOLECULE AFFINITY TO CEREBLON
    Publication number: 20210102938
    Abstract: A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.
    Type: Application
    Filed: September 18, 2020
    Publication date: April 8, 2021
    Applicant: CELGENE CORPORATION
    Inventors: Philip Paul CHAMBERLAIN, Mary MATYSKIELA, Godrej KHAMBATTA
  • Methods for measuring small molecule affinity to cereblon
    Patent number: 10816544
    Abstract: A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: October 27, 2020
    Assignee: CELGENE CORPORATION
    Inventors: Philip Paul Chamberlain, Mary Matyskiela, Godrej Khambatta
  • PD-1 binding proteins and methods of use thereof
    Patent number: 10428145
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: October 1, 2019
    Assignee: Celgene Corporation
    Inventors: Brydon Bennett, Philip Paul Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan
  • METHODS FOR MEASURING SMALL MOLECULE AFFINITY TO CEREBLON
    Publication number: 20180224435
    Abstract: A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.
    Type: Application
    Filed: February 2, 2018
    Publication date: August 9, 2018
    Inventors: Philip Paul CHAMBERLAIN, Mary MATYSKIELA, Godrej KHAMBATTA
  • PD-1 BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20170088618
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 30, 2017
    Inventors: Brydon Bennett, Philip Paul Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan