Abstract: 6-(2-(2H-tetrazol-5-yl)ethyl)-6-fluorodecahydroisoquinoline-3-carboxylic acid and 6-(2-(2H-tetrazol-5-yl)ethyl)-6-fluorodecahydroisoquinoline-3-carboxylic acid hydrocarbyl ester derivatives of formula are disclosed, as are pharmaceutical compositions and methods for the treatment of pain, epilepsy, convulsions, and seizures employing those compositions.

Abstract: 6-(2-(2H-tetrazol-5-yl)ethyl)-6-fluorodecahydroisoquinoline-3-carboxylic acid and 6-(2-(2H-tetrazol-5-yl)ethyl)-6-fluorodecahydroisoquinoline-3-carboxylic acid hydrocarbyl ester derivatives of formula are disclosed, as are pharmaceutical compositions and methods for the treatment of pain, epilepsy, convulsions, and seizures employing those compositions.

Abstract: A method comprising receiving first data representative of a query received by an electronic device. Device characteristic data indicative of at least one characteristic of the electronic device is received. It is determined, using the device characteristic data, that the electronic device is authorized to access a first portion of at least one knowledge graph, which is an access-controlled portion. The at least one knowledge graph also includes a second portion which is a non-access-controlled portion. The first data is sent to at least the first portion of the at least one knowledge graph. Second data is received from the first portion of the at least one knowledge graph. The second data is representative of an answer to the query. Answer data representative of the answer to the query is generated using the second data.

Abstract: Embodiments relate to formulations comprising sodium acetate trihydrate and other components. In addition, embodiments further relate to methods of preparing such formulations. Furthermore, embodiments relate to products including such formulations.

Abstract: Embodiments relate to formulations comprising sodium acetate trihydrate and other components. In addition, embodiments further relate to methods of preparing such formulations. Furthermore, embodiments relate to products including such formulations.

Abstract: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.

Abstract: The present disclosure relates to methods of using fatty acid amide hydrolase (FAAH) inhibitors alone or in combination for the treatment or prevention of abdominal, visceral or pelvic pain. Also described herein are pharmaceutical compositions comprising a FAAH inhibitor, alone or in combination with an additional therapeutic agent for the treatment of abdominal, visceral or pelvic pain.

Abstract: The present disclosure relates to methods of using fatty acid amide hydrolase (FAAH) inhibitors to treat aspects of Parkinson's disease (PD), restless legs syndrome (RLS) and periodic limb movement disorder (PLMD), the use of FAAH inhibitors for the manufacture of medicaments for use in the treatment of PD, RLS and PLMD, as well as pharmaceutically acceptable compositions comprising FAAH inhibitors for use in the treatment of PD, RLS and PLMD.

Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.

Abstract: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.

Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.

Abstract: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.

Abstract: A system and method for enabling the automatic setting of a mask for displaying live endoscopic images on a monitor device. An imaging node processor selects a pre-determined mask setting based on an automatically detected solid state imager (CCD) type when connected to the video processor, and a selected magnifying ratio. Based on this information, a mask pattern is automatically generated in a main memory. A merge function enables the mask to be displayed with cutout portions where information including, live or frozen image, thumbnail image associated with a static image capture, and patient demographic information is displayed. The user may select the frame coordinate locations corresponding to the corners of the live viewable area, captured image display and other system and demographic information to be displayed. Further, while the system is configured to include pre-defined masks, users are additionally able to create additional masks or modify the system-defined masks.

Abstract: A method and system for assisting a user in generating a report regarding a procedure such as a medical procedure. A first display region provides a hierarchical menu of available keywords from a knowledge base. A second display region provides a hierarchical menu of particular keywords that have been selected by the user. A third display region provides a report from a sentence that was generated by populating a sentence model based on the selected keywords. The sentence can be edited by selecting a keyword from the sentence, then selecting a replacement keyword from the first display region. A grammar engine corrects the grammar of the sentence based on user settings for the keywords.

Abstract: A method and system for capturing patient related data in an endoscopic system comprising an imaging node adapted to capture and display endoscopic images during the course of an endoscopic examination. The patient data capture system and method includes a display device that provides an interface to enable a user to enter data relating to a patient examined during the examination, including patient vital sign information at various phases of care relating to the endoscopic examination and, further including individual graphic controls for enabling entry of values relating to the patient's vitals information. The entered patients vitals information is associated with a timestamp. The patient vitals information and associated timestamps are stored in a database record associated with the patient. Further data capable of being entered into the system includes medications administered, Aldrete scores and intraprocedural assessments.

Abstract: A system and method for enabling the automatic setting of a mask for displaying live endoscopic images on a monitor device. An imaging node processor selects a pre-determined mask setting based on an automatically detected solid state imager (CCD) type when connected to the video processor, and a selected magnifying ratio. Based on this information, a mask pattern is automatically generated in a main memory. A merge function enables the mask to be displayed with cutout portions where information including, live or frozen image, thumbnail image associated with a static image capture, and patient demographic information is displayed. The user may select the frame coordinate locations corresponding to the corners of the live viewable area, captured image display and other system and demographic information to be displayed. Further, while the system is configured to include pre-defined masks, users are additionally able to create additional masks or modify the system-defined masks.

Abstract: A system designed to support and manage the workflow for all user roles pertaining to an endoscopic laboratory, from registration and scheduling of patient information through pre-procedure, procedure and post-procedure phases of an endoscopic examination, including support for the entry, by various users associated with an endoscopic laboratory, of information and data including the processing and storage of endoscopic images captured during an endoscopic exam of a patient, for association with a patient record stored in a database, and including the entry of procedure notes and generation of reports that include the stored images, all via an integrated user interface.