Patents by Inventor Philip Pitis

Philip Pitis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Opioid receptor ligands and methods of using and making same
    Patent number: 11931350
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: March 19, 2024
    Assignee: TREVENA, INC.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE
    Publication number: 20240018158
    Abstract: The present disclosure provides bifunctional compounds comprising a target protein binding moiety and a E3 ubiquitin ligase binding moiety, and associated methods of use.
    Type: Application
    Filed: May 15, 2023
    Publication date: January 18, 2024
    Inventors: Hong Lin, Philip Pitis, Liang Lu, Andrew Paul Combs
  • BRM targeting compounds and associated methods of use
    Patent number: 11702423
    Abstract: The present disclosure provides bifunctional compounds comprising a target protein binding moiety and a E3 ubiquitin ligase binding moiety, and associated methods of use.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: July 18, 2023
    Assignee: Prelude Therapeutics Incorporated
    Inventors: Hong Lin, Philip Pitis, Liang Lu, Andrew Paul Combs
  • Opioid Receptor Ligands And Methods Of Using And Making Same
    Publication number: 20220175747
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: July 2, 2021
    Publication date: June 9, 2022
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C.K. Yuan
  • SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)
    Publication number: 20220177481
    Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
    Type: Application
    Filed: February 17, 2022
    Publication date: June 9, 2022
    Inventors: Juan Luengo, Hong Lin, Michael Hawkins, Rupa Shetty, Philip Pitis, Gisela Saborit Villarroya
  • Selective Inhibitors Of Protein Arginine Methyltransferase 5 (PRMT5)
    Publication number: 20220152073
    Abstract: The disclosure is directed to methods of treatment using compounds of Formula (I).
    Type: Application
    Filed: April 3, 2020
    Publication date: May 19, 2022
    Inventors: Hong Lin, Juan Luengo, Rupa Shetty, Michael Hawkins, Philip Pitis, Gisela Saborit Villarroya
  • Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)
    Patent number: 11254683
    Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: February 22, 2022
    Assignee: Prelude Therapeutics Incorporated
    Inventors: Juan Luengo, Hong Lin, Michael Hawkins, Rupa Shetty, Philip Pitis, Gisela Saborit Villarroya
  • BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE
    Publication number: 20220033409
    Abstract: The present disclosure provides bifunctional compounds comprising a target protein binding moiety and a E3 ubiquitin ligase binding moiety, and associated methods of use.
    Type: Application
    Filed: June 9, 2021
    Publication date: February 3, 2022
    Inventors: Hong Lin, Philip Pitis, Liang Lu, Andrew Paul Combs
  • Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)
    Patent number: 11214574
    Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: January 4, 2022
    Assignee: Prelude Therapeutics, Incorporated
    Inventors: Juan Luengo, Hong Lin, Michael Hawkins, Rupa Shetty, Philip Pitis, Gisela Saborit Villarroya
  • Opioid receptor ligands and methods of using and making same
    Patent number: 11077098
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: August 3, 2021
    Assignee: Trevena, Inc.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)
    Publication number: 20200361945
    Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 19, 2020
    Inventors: Juan Luengo, Hong Lin, Michael Hawkins, Rupa Shetty, Philip Pitis, Gisela Saborit Villarroya
  • SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)
    Publication number: 20200291037
    Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Inventors: Juan Luengo, Hong Lin, Michael Hawkins, Rupa Shetty, Philip Pitis, Gisela Saborit Villarroya
  • Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)
    Patent number: 10711007
    Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: July 14, 2020
    Assignee: Prelude Therapeutics Incorporated
    Inventors: Juan Luengo, Hong Lin, Michael Hawkins, Rupa Shetty, Philip Pitis, Gisela Saborit Villarroya
  • Opioid receptor ligands and methods of using and making same
    Patent number: 10588898
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: March 17, 2020
    Assignee: TREVENA, INC.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • Opioid Receptor Ligands And Methods Of Using And Making Same
    Publication number: 20190343819
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • Opioid Receptor Ligands And Methods Of Using And Making Same
    Publication number: 20180311222
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: December 1, 2017
    Publication date: November 1, 2018
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C.K. Yuan
  • Opioid receptor ligands and methods of using and making same
    Patent number: 9849119
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: December 26, 2017
    Assignee: TREVENA, INC.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • Opioid Receptor Ligands And Methods Of Using And Making Same
    Publication number: 20170326124
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: March 29, 2017
    Publication date: November 16, 2017
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C.K. Yuan
  • Opioid receptor ligands and methods of using and making same
    Patent number: 9642842
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: May 9, 2017
    Assignee: Trevana, Inc.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • Opioid Receptor Ligands And Methods Of Using And Making Same
    Publication number: 20160250199
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: April 7, 2016
    Publication date: September 1, 2016
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C.K. Yuan