Patents by Inventor Philip R. LeDuc

Philip R. LeDuc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220269168
    Abstract: A method of replicating master molds used in the fabrication of microsystems having micron to millimeter sized features. Master molds are replicating using a polymer sheet, which is heated and melted onto an elastomeric mold fabricated from the master mold. The copy molds accurately replicate the geometries of the master mold, such as high aspect ratio features, microposts, and channels with slender sidewalls. The polymer sheet encases the elastomeric mold without the application of an external force, permitting copying without deformation of the features.
    Type: Application
    Filed: February 25, 2022
    Publication date: August 25, 2022
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Philip R. LeDuc, Utku Sonmez
  • Publication number: 20220081329
    Abstract: Provided herein are highly porous electrode structures made from natural materials and retaining natural architecture, which are highly permeable and find use in capacitive deionization desalination systems and methods. Also provided herein are methods of making the electrodes and desalination systems, as well as methods of desalinating water.
    Type: Application
    Filed: January 27, 2020
    Publication date: March 17, 2022
    Inventors: Alan J. Russell, Philip R. LeDuc, Adam Wood
  • Publication number: 20210178636
    Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 17, 2021
    Applicants: CARNEGIE MELLON UNIVERSITY, University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Philip R. LeDuc, O. Burak Ozdoganlar, Mary E. Wilson, Emrullah Korkmaz, Yadong Wang, Donna Beer-Stolz
  • Patent number: 10919183
    Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: February 16, 2021
    Assignees: CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Philip R. LeDuc, O. Burak Ozdoganlar, Mary E. Wilson, Emrullah Korkmaz, Yadong Wang, Donna Beer-Stolz
  • Publication number: 20200047401
    Abstract: A method and device for fabricating vascular networks in for tissue engineering. The vascular network is embedded in a porous scaffold and is created from a sacrificial wax template, according to one embodiment. A extrusion-based three dimensional printer is used to create the template, wherein the printer utilizes an extruder incorporating a mixer to maintain the consistency of the extrudate.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Zhou Yu, Philip R. LeDuc, O. Burak Ozdoganlar
  • Publication number: 20200029428
    Abstract: A flexible and stretchable integrated electronic device comprising a substrate having a stiffness gradient, wherein a rigid electronic device is embedded within the substrate. The stiffness gradient within the substrate prevents delamination at the interface between the substrate and the embedded device. A method of fabricating an integrated electronic device having a stiffness gradient comprises applying a curing agent to an uncured polymer base material.
    Type: Application
    Filed: September 17, 2019
    Publication date: January 23, 2020
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Gary K. Fedder, Carmel Majidi, Philip R. LeDuc, Lee E. Weiss, Christopher J. Bettinger, Naser Naserifar
  • Patent number: 10462897
    Abstract: A flexible and stretchable integrated electronic device comprising a substrate having a stiffness gradient, wherein a rigid electronic device is embedded within the substrate. The stiffness gradient within the substrate prevents delamination at the interface between the substrate and the embedded device. A method of fabricating an integrated electronic device having a stiffness gradient comprises applying a curing agent to an uncured polymer base material.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: October 29, 2019
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Gary K. Fedder, Carmel Majidi, Philip R. LeDuc, Lee E. Weiss, Christopher J. Bettinger, Naser Naserifar
  • Publication number: 20180206336
    Abstract: A flexible and stretchable integrated electronic device comprising a substrate having a stiffness gradient, wherein a rigid electronic device is embedded within the substrate. The stiffness gradient within the substrate prevents delamination at the interface between the substrate and the embedded device. A method of fabricating an integrated electronic device having a stiffness gradient comprises applying a curing agent to an uncured polymer base material.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 19, 2018
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Gary K. Fedder, Carmel Majidi, Philip R. LeDuc, Lee E. Weiss, Christopher J. Bettinger, Naser Naserifar
  • Patent number: 9976113
    Abstract: This invention provides an apparatus and method for culturing cells to probe the influence that the properties of a surface onto which the cells are bonded has on the properties of the cell.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: May 22, 2018
    Assignees: Agency for Science, Technology and Research, Carnegie Mellon University
    Inventors: Yukai Zeng, Philip R. Leduc, Keng-Hwee Chiam
  • Publication number: 20160160165
    Abstract: This invention provides an apparatus and method for culturing cells to probe the influence that the properties of a surface onto which the cells are bonded has on the properties of the cell.
    Type: Application
    Filed: August 7, 2014
    Publication date: June 9, 2016
    Inventors: Yukai Zeng, Philip R. Leduc, Keng-Hwee Chiam
  • Publication number: 20160122701
    Abstract: Described herein are devices, systems and methods for lysing algae cells, for production of a lysate product such as a biofuel. The systems and methods use a passive device that lyses the cells through flow configurations, geometries, and surfaces that would induce different stresses and negative pressure on the microalgae cells. When the stress is designed to exceed the mechanical strength of the microalgae cells, the cells are lysed, causing, e.g., lipid release which can be used to produce biofuels. Through an internally-created computational framework, the concept is validated and can be optimized for the lowest energy input with the highest level of lipid release. Also provided herein are computer-implemented methods for optimizing lysis in such systems and computer-readable media containing instructions for performing the computer-implemented methods.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 5, 2016
    Inventors: C. Fred Higgs, III, Philip R. LeDuc, Kristin M. Warren, Jeremiah N. Mpagazehe
  • Publication number: 20150376595
    Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.
    Type: Application
    Filed: June 25, 2015
    Publication date: December 31, 2015
    Applicants: CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation, University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Philip R. LeDuc, O. Burak Ozdoganlar, Mary E. Wilson, Emrullah Korkmaz, Yadong Wang, Donna Beer-Stolz
  • Patent number: 8695618
    Abstract: Methods of controllably creating three-dimensional (3D) combined-flow-interface patterns in multi-lane fluidic devices, and systems, apparatuses and software therefor. In one example, the 3D-pattern is created and varied as a function of one or more of the geometry of the inlets to a main fluidic channel in which the 3D-pattern is formed, the Reynolds number of the flows, the dimensions of the main fluidic channel and the inlets, and the spacing of adjacent inlets. In one embodiment particularly disclosed, differing 3D combined-flow-interface patterns are created using a three-lane fluidic device having a fixed inlet geometry. In another embodiment particularly disclosed, differing 3D combined-flow-interface patterns are created using a five-lane fluidic device having a fixed inlet geometry that can be used to effectively mimic variable inlet geometries.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: April 15, 2014
    Assignee: Carnegie Mellon University
    Inventors: Yong Tae Kim, William C. Messner, Philip R. LeDuc
  • Publication number: 20130014828
    Abstract: Methods of controllably creating three-dimensional (3D) combined-flow-interface patterns in multi-lane fluidic devices, and systems, apparatuses and software therefor. In one example, the 3D-pattern is created and varied as a function of one or more of the geometry of the inlets to a main fluidic channel in which the 3D-pattern is formed, the Reynolds number of the flows, the dimensions of the main fluidic channel and the inlets, and the spacing of adjacent inlets. In one embodiment particularly disclosed, differing 3D combined-flow-interface patterns are created using a three-lane fluidic device having a fixed inlet geometry. In another embodiment particularly disclosed, differing 3D combined-flow-interface patterns are created using a five-lane fluidic device having a fixed inlet geometry that can be used to effectively mimic variable inlet geometries.
    Type: Application
    Filed: December 22, 2011
    Publication date: January 17, 2013
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Yong Tae Kim, William C. Messner, Philip R. LeDuc
  • Publication number: 20120264065
    Abstract: A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.
    Type: Application
    Filed: May 11, 2012
    Publication date: October 18, 2012
    Inventors: Chao-Min Cheng, Bin Li, Philip R. LeDuc
  • Patent number: 8192922
    Abstract: A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.
    Type: Grant
    Filed: October 3, 2006
    Date of Patent: June 5, 2012
    Assignee: Carnegie Mellon University
    Inventors: Chao-Min Cheng, Bin Li, Philip R. LeDuc
  • Publication number: 20090233241
    Abstract: A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.
    Type: Application
    Filed: October 3, 2006
    Publication date: September 17, 2009
    Inventors: Chao-min Cheng, Bin Li, Philip R LeDuc