Patents by Inventor Philip Rosenstiel

Philip Rosenstiel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXO1 Promotor Polymorphism Associated with Exceptional Life Expectancy in Humans
    Publication number: 20110027783
    Abstract: The invention relates to an exonuclease 1 (EXO1) promoter polymorphism associated with exceptional life expectancy in humans. More specifically, the invention relates to the promoter region of EXO1 where the gene has been found to be mutated. Moreover, the invention relates to a gene regulation mechanism involving transcription factor E47 as a transcriptional repressor of EXO1.
    Type: Application
    Filed: December 22, 2008
    Publication date: February 3, 2011
    Applicant: UNIVERSITAETSKLINIKUM SCHLESWIG-HOLSTEIN
    Inventors: Stefan Schreiber, Almut Nebel, Andreas Till, Friederike Flachsbart, Philip Rosenstiel
  • METHODS AND AGENTS FOR EVALUATING INFLAMMATORY BOWEL DISEASE, AND TARGETS FOR TREATMENT
    Publication number: 20100167285
    Abstract: The invention provides methods for evaluating irritable bowel disease (IBD), including Crohn Disease and Ulcerative Colitis, methods for determining a patient's susceptibility to developing an IBD, and methods for determining a patient's IBD genotype. The invention includes methods, polynucleotides, polypeptides, and antibodies relating to disclosed variants of, and polymorphisms in, the nel-like 1 precursor (NELL1), as well as the 5p13.1 locus, and other genes disclosed herein to be associated with IBD. Thus, the invention provides diagnostic and/or therapeutic targets for IBD, as well as diagnostic and therapeutic agents for IBD.
    Type: Application
    Filed: March 26, 2008
    Publication date: July 1, 2010
    Inventors: Stefan Schreiber, Philip Rosenstiel, Andreas Ruether, Andre Franke, John Raelson, Randall D. Little, Tim Keith, Helene Fournier