Patents by Inventor Philip Rybczynski

Philip Rybczynski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for preventing and/or treating lysosomal storage disorders
    Patent number: 10035766
    Abstract: The present invention provides novel compositions as well as methods for preventing and/or treating lysosomal storage disorders. In particular, the present invention provides methods for preventing and/or treating Gaucher's disease.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: July 31, 2018
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • NOVEL COMPOSITIONS FOR PREVENTING AND/OR TREATING DEGENERATIVE DISORDERS OF THE CENTRAL NERVOUS SYSTEM
    Publication number: 20160326114
    Abstract: The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease.
    Type: Application
    Filed: July 22, 2016
    Publication date: November 10, 2016
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • Compositions for preventing and/or treating degenerative disorders of the central nervous system
    Patent number: 9409862
    Abstract: The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: August 9, 2016
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • Substituted dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 8796313
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: August 5, 2014
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Joseph Dudash, Philip Rybczynski, Maud Urbanski, Amy Xiang, Roxanne Zeck, Xiaoyan Zhang, Yongzheng Zhang
  • Novel Compositions for Preventing and/or Treating Lysosomal Storage Disorders
    Publication number: 20140086896
    Abstract: The present invention provides novel compositions as well as methods for preventing and/or treating lysosomal storage disorders. In particular, the present invention provides methods for preventing and/or treating Gaucher's disease.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 27, 2014
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • Novel Compositions for Preventing and/or Treating Degenerative Disorders of the Central Nervous System
    Publication number: 20140080871
    Abstract: The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 20, 2014
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • NEW METHOD FOR PREPARING ISOFAGOMINE AND ITS DERIVATIVES
    Publication number: 20140005372
    Abstract: A method for preparing isofagomine, its derivatives, intermediates and salts thereof using novel processes to make isofagomine from D-(?)-arabinose and L-(?)-xylose.
    Type: Application
    Filed: June 12, 2013
    Publication date: January 2, 2014
    Inventors: Philip Rybczynski, Alexander Tretyakov, Dan Fuerst, Kamlesh Sheth
  • Compositions for preventing and/or treating degenerative disorders of the central nervous system
    Patent number: 8604206
    Abstract: The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: December 10, 2013
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • Compositions for preventing and/or treating lysosomal storage disorders
    Patent number: 8604057
    Abstract: The present invention provides novel compositions as well as methods for preventing and/or treating lysosomal storage disorders. In particular, the present invention provides methods for preventing and/or treating Gaucher's disease.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: December 10, 2013
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • Method for preparing isofagomine and its derivatives
    Patent number: 8487110
    Abstract: A method for preparing isofagomine, its derivatives, intermediates and salts thereof using novel processes to make isofagomine from D-(?)-arabinose and L-(?)-xylose.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: July 16, 2013
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Philip Rybczynski, Alexander Tretyakov, Dan Fuerst, Kamlesh Sheth
  • NOVEL COMPOSITIONS FOR PREVENTING AND/OR TREATING DEGENERATIVE DISORDERS OF THE CENTRAL NERVOUS SYSTEM
    Publication number: 20110092541
    Abstract: The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease.
    Type: Application
    Filed: October 5, 2010
    Publication date: April 21, 2011
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • NOVEL COMPOSITIONS FOR PREVENTING AND/OR TREATING LYSOSOMAL STORAGE DISORDERS
    Publication number: 20110091442
    Abstract: The present invention provides novel compositions as well as methods for preventing and/or treating lysosomal storage disorders. In particular, the present invention provides methods for preventing and/or treating Gaucher's disease.
    Type: Application
    Filed: October 5, 2010
    Publication date: April 21, 2011
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Robert Boyd, Gary Lee, Philip Rybczynski
  • Dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 7928246
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • Tartrate salt of isofagomine and methods of use
    Patent number: 7863453
    Abstract: A novel tartaric acid salt of Isofagomine (Isofagomine tartrate) that can be used for the treatment of Gaucher disease is provided. The invention also provides a crystalline form of isofagomine tartrate, method for preparing the salt, a pharmaceutical composition containing the salt, and a method of treating Gaucher disease.
    Type: Grant
    Filed: February 23, 2009
    Date of Patent: January 4, 2011
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Benjamin Mugrage, Kamlesh A. Sheth, David Palling, Philip Rybczynski
  • Substituted spiroheterocycles
    Patent number: 7825110
    Abstract: The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal insufficiency, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: November 2, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Min A. Xiang, Mona Patel, Philip Rybczynski, Joseph Gunnet, Keith T. Demarest, Richard Look, Bruce Maryanoff, Michael J. Costanzo, Stephen C. Yabut
  • Substituted spiroheterocycles
    Patent number: 7825111
    Abstract: The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: November 2, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Min A. Xiang, Mona Patel, Philip Rybczynski, Joseph Gunnet, Keith T. Demarest, Richard Look, Bruce Maryanoff, Michael J. Costanzo, Stephen C. Yabut
  • Substituted indole-O-glucosides
    Patent number: 7820630
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 26, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted fused heterocyclic C-glycosides
    Patent number: 7816328
    Abstract: This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: October 19, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • NEW METHOD FOR PREPARING ISOFAGOMINE AND ITS DERIVATIVES
    Publication number: 20100160638
    Abstract: A method for preparing isofagomine, its derivatives, intermediates and salts thereof using novel processes to make isofagomine from D-(?)-arabinose and L-(?)-xylose.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 24, 2010
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Philip Rybczynski, Alexander Tretyakov, Dan Fuerst, Kamlesh Sheth
  • SUBSTITUTED INDOLE-O-GLUCOSIDES
    Publication number: 20100009900
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 14, 2010
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang