Patents by Inventor Philip Starkey Lewis

Philip Starkey Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TRANSFECTING MACROPHAGES
    Publication number: 20230265389
    Abstract: The development of the method of the invention enables the efficient and reproducible production of genetically modified GMP-grade human macrophages. The inventors have described the effects of the method described on cell viability and efficiency of introduction of genetic material into macrophages. Unlike previous methods of introducing genetic material into macrophages, excellent conditions are demonstrated which produce efficient transgene expression, without compromising cell viability. Critically, the method of the invention does not use virus to introduce genetic material, is efficacious on mature cells, are functional with in vitro assay and in vivo transfer in a liver disease model and complies with practices compatible with manufacture and delivery of these cells to patients.
    Type: Application
    Filed: May 27, 2021
    Publication date: August 24, 2023
    Inventors: Stuart Forbes, Lara Campana, Benjamin Dwyer, Philip Starkey Lewis, John Campbell, Alasdair Fraser
  • Macrophage-based therapy for use in the treatment of liver injury
    Patent number: 11285174
    Abstract: The present invention relates to alternatively activated macrophages (AAMs) for use in the treatment of liver injury and methods of treating and preventing liver injury using AAMs.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: March 29, 2022
    Assignee: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
    Inventors: Stuart Forbes, Philip Starkey Lewis, Lesley Forrester
  • MACROPHAGE-BASED THERAPY FOR USE IN THE TREATMENT OF LIVER INJURY
    Publication number: 20190240256
    Abstract: The present invention relates to alternatively activated macrophages (AAMs) for use in the treatment of liver injury and methods of treating and preventing liver injury using AAMs.
    Type: Application
    Filed: September 18, 2017
    Publication date: August 8, 2019
    Inventors: Stuart Forbes, Philip Starkey Lewis, Lesley Forrester