Patents by Inventor Philip Stewart Low et al.

Philip Stewart Low et al. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT FIBROBLAST-TARGETED AGENTS AND METHODS OF USE
    Publication number: 20220265870
    Abstract: Multivalent ligand-targeted active agents, such as detectable agents or therapeutic agents, for the imaging and treatment, respectively, of fibroblast activation protein (FAP)-positive cancer-associated fibroblasts (CAFs) and activated myofibroblasts in cancers and other fibrotic diseases.
    Type: Application
    Filed: July 22, 2020
    Publication date: August 25, 2022
    Inventors: Philip Stewart Low et al., Madduri Srinivasarao, Ramesh Mukkamala
  • REJUVENATION OF CAR T CELL
    Publication number: 20210308267
    Abstract: A payload of drug conjugated to a targeting ligand specifically designed to deliver to exhausted CART cells to rejuvenate these CAR T cells is provided herein. The targeted CAR T cells are modified with a fusion receptor which can bind to the targeting ligand and internalize the conjugated payload of drug to execute its regulatory function to exhausted CAR T cell.
    Type: Application
    Filed: July 21, 2019
    Publication date: October 7, 2021
    Inventors: Philip Stewart Low et al., Boning Zhang, John V. Napoleon