Patents by Inventor Philip T. Cherian

Philip T. Cherian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bisphosphonate quinolone conjugates and uses thereof
    Patent number: 11840549
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: December 12, 2023
    Assignees: BIOVINC, LLC, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Frank H. Ebetino, Shuting Sun, Mark W. Lundy, Charles E. McKenna, Eric Richard, Parish Sedghizadeh, Keivan Sadrerafi, Philip T. Cherian
  • BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF
    Publication number: 20210101920
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 11, 2020
    Publication date: April 8, 2021
    Inventors: Frank H. EBETINO, Shuting SUN, Mark W. LUNDY, Charles E. MCKENNA, Eric RICHARD, Parish SEDGHIZADEH, Keivan SADRERAFI, Philip T. CHERIAN
  • Bisphosphonate quinolone conjugates and uses thereof
    Patent number: 10865220
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: December 15, 2020
    Assignees: BIOVINC, LLC, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Frank H. Ebetino, Shuting Sun, Mark W. Lundy, Charles E. McKenna, Eric Richard, Parish Sedghizadeh, Keivan Sadrerafi, Philip T. Cherian
  • BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF
    Publication number: 20190169214
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 6, 2019
    Inventors: Frank H. EBETINO, Shuting SUN, Mark W. LUNDY, Charles E. MCKENNA, Eric RICHARD, Parish SEDGHIZADEH, Keivan SADRERAFI, Philip T. CHERIAN
  • Treatments for gastrointestinal conditions
    Patent number: 10011589
    Abstract: Compounds for the treatment of bacterial and parasitic infections which are hybrid compounds of compounds having antibacterial or antiparasitic activity and compounds that decrease the absorption of the hybrid compound from the gastrointestinal tract. The compounds are preferably for use against C. difficile infections and comprise a hybrid molecule of an anti-C. difficile compound such as a nitroimidazole and a tetramic acid derivative.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: July 3, 2018
    Assignees: Board of Regents, The University of Texas System, St. Jude Children's Research Hospital, Inc.
    Inventors: Richard E. Lee, Philip T. Cherian, Julian G. Hurdle, Xiaoqian Wu
  • Treatments for Gastrointestinal Conditions
    Publication number: 20170073332
    Abstract: Compounds for the treatment of bacterial and parasitic infections which are hybrid compounds of compounds having antibacterial or antiparasitic activity and compounds that decrease the absorption of the hybrid compound from the gastrointestinal tract. The compounds are preferably for use against C. difficile infections and comprise a hybrid molecule of an anti-C. difficile compound such as a nitroimidazole and a tetramic acid derivative.
    Type: Application
    Filed: March 12, 2015
    Publication date: March 16, 2017
    Inventors: Richard E. Lee, Philip T. Cherian, Julian G. Hurdle, Xiaoqian WU