Abstract: Disclosed herein are methods and compositions for targeted integration of an exogenous sequence into the human PPP1R12C locus, for example, for expression of a polypeptide of interest.

Abstract: A jacking tower installation system comprises a jacking tower having at least two forward and at least two rear legs, wherein each of the legs is supported on one of a plurality of support stands attached to and horizontally offset from the leg, the legs including dollies which enable horizontal movement of the jacking tower and lifts capable of raising and lowering the jacking tower clear of the sill beams of a cargo container crane, such that the legs of the jacking tower can be lifted and positioned over and lowered onto the sill beams.

Abstract: A jacking tower installation system comprises a jacking tower having at least two forward and at least two rear legs, wherein each of the legs is supported on one of a plurality of support stands attached to and horizontally offset from the leg, the legs including dollies which enable horizontal movement of the jacking tower and lifts capable of raising and lowering the jacking tower clear of the sill beams of a cargo container crane, such that the legs of the jacking tower can be lifted and positioned over and lowered onto the sill beams.

Abstract: A cargo container handling cart and system comprises a plurality of cargo container handling carts 10, each cart comprising a frame 12 supported on wheels 16, the frame having two support surfaces 26 and at least one centrally disposed container guide 20, each support surface having two cart pins 32, and a cart end edge 28, the support surface 26 bounded by the container guide 20 and the cart end edge 28 for supporting the end of a cargo container, wherein the support surface 26 has a width substantially equivalent to a standard cargo container, the container guide 20 abuts a container end resting on one of the support surfaces 26, and the cart pins 32 extend upwardly from the support surface 26 between the container guide 20 and the cart end edge 28 for engaging with the corner casting holes of the corner fittings of the container end for holding the container end on the support surface 26 against the container guide 20.

Abstract: Nucleases and methods of using these nucleases for alteration of a CFTR gene and generation of cells and animal models.

Abstract: A removable frame for detachable mounting onto a trailer flatbed chassis for suspending a carrier beam extending transversely to and beyond the lateral edges of the chassis, the carrier beam having a pair of movable trolley hoists suspended therefrom whereby cargo can be loaded onto and off from both sides of the bed of the trailer chassis.

Abstract: A cargo container handling cart and system comprises a plurality of cargo container handling carts 10, each cart comprising a frame 12 supported on wheels 16, the frame having two support surfaces 26 and at least one centrally disposed container guide 20, each support surface having two cart pins 32, and a cart end edge 28, the support surface 26 bounded by the container guide 20 and the cart end edge 28 for supporting the end of a cargo container, wherein the support surface 26 has a width substantially equivalent to a standard cargo container, the container guide 20 abuts a container end resting on one of the support surfaces 26, and the cart pins 32 extend upwardly from the support surface 26 between the container guide 20 and the cart end edge 28 for engaging with the corner casting holes of the corner fittings of the container end for holding the container end on the support surface 26 against the container guide 20.

Abstract: A removable frame for detachable mounting onto a trailer flatbed chassis for suspending a carrier beam extending transversely to and beyond the lateral edges of the chassis, the carrier beam having a pair of movable trolley hoists suspended therefrom whereby cargo can be loaded onto and off from both sides of the bed of the trailer chassis.

Abstract: A shield for radiation used for scanning freight containers is relocatable by cranes and lifts found in freight terminals. The relocatable radiation shield comprises a shield block having at least one solid shielding layer. A layer of the relocatable shield is adapted to hold a shielding fluid for altering a shielding property of the relocatable shield. The fluid-containing layer may optionally be a fluid container attached to or partially embedded within the shield block. The shielding fluid may be removed to reduce the weight of the relocatable radiation shield. In some embodiments the relocatable shield has a channel large enough for passage of a freight container on a conveyance such as a railroad car. An extended shielding structure for shielding a selected path may be assembled from two or more relocatable radiation shields. Some embodiments of a relocatable radiation shield include a freight container.

Abstract: A mobile cargo container handling buffer crane having a bridge crane mounted thereon for transferring cargo containers between a ship and land transportation with nonintrusive inspection apparatus located at an intermediate transfer position past which a container can be longitudinally translated on a shuttle and thereby non-intrusively inspected.

Abstract: A mobile cargo container handling buffer crane having a bridge crane mounted thereon for transferring cargo containers between a ship and land transportation with an intermediate transfer position at which a suspended container can be noninvasively inspected by a longitudinally reciprocating container traversing nonintrusive inspection apparatus.

Abstract: A method for nonintrusive scanning of cargo containers quay side while the containers are being transferred between ship and land transportation utilizing a mobile cargo container handling buffer crane having a bridge crane mounted thereon for transferring cargo containers between a ship and land transportation with an intermediate transfer position whereby a suspended container can be noninvasively inspected by a longitudinally reciprocating container traversing radiation emitter apparatus.