Patents by Inventor Philip W. Payne

Philip W. Payne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dantagonists, methods of synthesis and methods of use
    Patent number: 9156840
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: October 13, 2015
    Assignee: ALTOS THERAPEUTICS, LLC
    Inventors: Gary W. Luehr, Arathi Sundaram, Priyadarshini Jaishankar, Philip W Payne, Pascal Druzgala
  • APOE IMMUNOTHERAPY
    Publication number: 20140348843
    Abstract: The present invention provides antibodies that preferentially bind to an ApoE(1-272) fragment relative to ApoE(1-299). These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of neurological diseases.
    Type: Application
    Filed: May 28, 2014
    Publication date: November 27, 2014
    Applicant: NEOTOPE BIOSCIENCES LIMITED
    Inventors: Dale B. Schenk, Tarlochan S. Nijjar, Philip W. Payne, Robin Barbour
  • D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE
    Publication number: 20140350005
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Application
    Filed: February 19, 2014
    Publication date: November 27, 2014
    Inventors: GARY W. LUEHR, ARATHI SUNDARAM, PRIYADARSHINI JAISHANKAR, PHILIP W. PAYNE, PASCAL DRUZGALA
  • APOE immunotherapy
    Patent number: 8741298
    Abstract: The present invention provides antibodies that preferentially bind to an ApoE(1-272) fragment relative to ApoE(1-299). These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of neurological diseases.
    Type: Grant
    Filed: February 7, 2012
    Date of Patent: June 3, 2014
    Assignee: Neotope Biosciences Limited
    Inventors: Dale B. Schenk, Tarlochan S. Nijjar, Philip W. Payne, Robin Barbour
  • Dantagonists, methods of synthesis and methods of use
    Patent number: 8691836
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: April 8, 2014
    Assignee: Altos Therapeutics, LLC
    Inventors: Gary W. Luehr, Arathi Sundaram, Priyadarshini Jaishankar, Philip W. Payne, Pascal Druzgala
  • APOE IMMUNOTHERAPY
    Publication number: 20140050733
    Abstract: The present invention provides antibodies that preferentially bind to an ApoE(1-272) fragment relative to ApoE(1-299). These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of neurological diseases.
    Type: Application
    Filed: February 7, 2012
    Publication date: February 20, 2014
    Inventors: Dale B. Schenk, Tarlochan S. Nijjar, Philip w. Payne, Robin Barbour
  • APOE IMMUNOTHERAPY
    Publication number: 20120204275
    Abstract: The present invention provides antibodies that preferentially bind to an ApoE(1-272) fragment relative to ApoE(1-299). These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of neurological diseases.
    Type: Application
    Filed: February 7, 2012
    Publication date: August 9, 2012
    Applicant: Neotope Biosciences Limited
    Inventors: Dale B. Schenk, Tarlochan S. Nijjar, Philip W. Payne, Robin Barbour
  • D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE
    Publication number: 20120010228
    Abstract: Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
    Type: Application
    Filed: June 17, 2011
    Publication date: January 12, 2012
    Inventors: Gary W. Luehr, Arathi Sundaram, Priyadarshini Jaishankar, Philip W. Payne, Pascal Druzgala
  • Bubble silencer for an underwater voice communicator
    Patent number: 4527658
    Abstract: A bubble silencer for use with scuba equipment is comprised of a flat flexible enclosure attached to a scuba regulator valve. Exhaust bubbles issuing from the regulator into the enclosure coalesce into large air parcels to be expelled at low velocity through a rearward exit port. The large size and low velocity of the exhaust bubbles leaving the enclosure are much quieter than the small high velocity bubbles issuing from the regulator itself.
    Type: Grant
    Filed: July 31, 1984
    Date of Patent: July 9, 1985
    Inventor: Philip W. Payne
  • Tapered tube impedance matching underwater voice communicator with bubble silencer
    Patent number: 4527657
    Abstract: An underwater voice communicator in which the preferred embodiment comprises a pair of tapered tubes in communication with a diver's mouth. The tubes are constructed of a material having a sound impedance similar to the sound impedance of water. Sound energy issuing from the mouth of a diver is reflected down the length of the tapered tubes to an area of the tube that concentrates the sound for injection into the surrounding water.
    Type: Grant
    Filed: July 31, 1984
    Date of Patent: July 9, 1985
    Inventor: Philip W. Payne
  • Diver's fish spear
    Patent number: 4024665
    Abstract: The fish spear includes a shaft with scissor-like blades on one end, the front edges of the blades defining barbs and the back edges being smooth. When the blades are in closed position, a spear shape is defined for spearing a fish. When the blades open past each other, the front edges with the barbs penetrate the flesh of the fish and retain the fish on the spear. A manually operable pull cable connected to the blades will move them to their closed position, thus retracting the barbs and permitting easy removal of the spear from the fish.
    Type: Grant
    Filed: March 17, 1976
    Date of Patent: May 24, 1977
    Inventor: Philip W. Payne