Patents by Inventor Philip Whitcome

Philip Whitcome has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain imidazoquinoxalines; a new class of GABA brain receptor ligands
    Patent number: 5744602
    Abstract: The invention encompasses compounds of the formula: ##STR1## and the pharmaceutically acceptable salts thereof wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and X are variables; andW is phenyl optionally substituted with straight or branched chain lower alkyl having 1-6 carbon atoms or straight or branched chain lower alkoxy having 1-6 carbon atoms.These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine drugs, and enhancement of memory.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: April 28, 1998
    Assignee: Neurogen Corporation
    Inventors: Philip Whitcome, Kenneth Shaw