Abstract: One exemplary surgical apparatus may include at least one carrier, staples fixed to a corresponding carrier, and a feeder belt to which at least one carrier is frangibly connected.

Abstract: One example of a surgical method of treating tissue within the body of a patient may include providing a surgical instrument that includes a handle; a shaft extending from the handle, an end effector connected to the shaft, where the shaft includes a lumen defined therethrough and an articulated region; and at least one feeder belt extending through the lumen of the shaft into the end effector, where the feeder belt includes at least one staple frangibly united therewith; inserting the end effector into the body of a patient; orienting the end effector relative to tissue to be treated within the body of the patient and relative to a remainder of the shaft; actuating the end effector to staple tissue; and removing the end effector from the body of the patient.

Abstract: An exemplary surgical apparatus may include a flexible articulation insert separated into segments, where at least one segment is longitudinally slidable relative to at least one other segment, and where at least one passage is defined longitudinally through the insert; and at least one feeder belt extending through a corresponding passage in the insert, where staples are frangibly connected to the feeder belt.

Abstract: An exemplary surgical apparatus may include an anvil with a body having a cavity defined therein, and at least one insert fixed within the cavity. Another exemplary surgical apparatus may include an anvil with an upper layer composed of a first material, and a lower layer composed of a second material different from the first material, where the lower layer is fixed to the upper layer. A method of manufacturing a surgical apparatus may include fabricating an anvil that includes a insert composed of a first material, the insert located within a cavity in a body composed of a second material, where the first material and the second material have different properties.

Abstract: One example of a surgical instrument may include a staple holder; staples held by the staple holder; an anvil, where at least one of the staple holder and anvil is movable relative to the other; and at least one electrode located on a surface of the staple holder and/or anvil. Another example of a surgical instrument may include a staple holder; staples held by the staple holder; an anvil, where at least one of the staple holder and the anvil is movable relative to the other between an open configuration and a closed configuration; where an adjustable gap exists between the staple holder and the anvil in the closed configuration; and at least one electrode located on a surface of at least one of the staple holder and/or anvil. An exemplary method may include providing a surgical instrument including an end effector; clamping tissue with the end effector; selecting stapling or electrocautery; and stapling or performing electrocautery accordingly.

Abstract: One exemplary surgical apparatus may include at least one carrier, staples fixed to a corresponding carrier, and a feeder belt to which at least one carrier is frangibly connected. Another exemplary surgical apparatus may include a staple holder, an anvil movably connected to the staple holder, a feeder belt, where at least part of the feeder belt extends into the staple holder, and staples fixed to and frangibly separable from the feeder belt; where the staples are organized into at least two groups spaced apart from one another; and where at least one staple is deployable to a different closed shape than at least one other staple.

Abstract: An exemplary surgical stapler may include a staple holder, staples positioned within the staple holder, and at least one structure slidable within the staple holder to contact directly at least one staple, where that direct contact deploys at least one staple from the staple holder. Another exemplary surgical stapler may include a staple holder, an anvil movably connected to the staple holder, staples positioned within the staple holder; and a sled slidable within the staple holder to contact directly at least one staple, where that direct contact urges at least one staple out of the staple holder and against the anvil.

Abstract: One example of a surgical instrument may include a handle, an end effector, and a shaft that connects the handle to the end effector, where the shaft includes an articulated region. At least one feeder belt may extend through the lumen of the shaft into the end effector, where at least one feeder belt may include at least one staple frangibly connected thereto.

Abstract: A method for closing a patent foramen ovale in the heart tissue of a patient may include percutaneously advancing a connector applicator to the patent foramen ovale, registering the connector applicator with the patent foramen ovale, deploying connectors into heart tissue to close the patent foramen ovale; and percutaneously removing the connector applicator from the heart. One or more anchors may be used to register the connector applicator with the patent foramen ovale. The connector applicator may include a driver having a longitudinal passage therein, where at least part of at least one connector is positioned within the passage.

Abstract: An integrated anastomosis tool may include an effector that both makes an opening in the wall of a target vessel and connects a graft vessel to the target vessel. The connection between the graft vessel and the target vessel may be compliant, and may be achieved by deploying a plurality of connectors such as staples into tissue. The effector may include a cutter assembly and a connection module that are independently actuatable. The cutter assembly and/or the connection module may be cable-actuated.

Abstract: An anastomosis tool includes a handle connected to a tissue effector that may be capable of being oriented in two or more positions relative to the handle. The tissue effector holds a graft vessel having at least one flap defined in at least one end thereof against the side of a target vessel. Actuation of a trigger or other mechanism on the handle causes the tissue effector to deploy one or more connectors into the flaps of the graft vessel and the side of the target vessel, thereby connecting the graft vessel to the target vessel.

Abstract: A method for anastomosing a first vessel to a second vessel may include connecting an end of the first vessel to the side of the second vessel and creating an opening in the wall of the second vessel from within the lumen of the second vessel, where that opening allows fluid communication between the lumen of the first vessel and the lumen of the second vessel.

Abstract: An anastomosis tool may include a tissue effector having an anvil and a staple holder movable relative to one another, where that tissue effector may be movable from an open position to a closed position. A fluid-driven actuator may be utilized to move the tissue effector between those positions, and/or to deploy connectors from the staple holder when the tissue effector is in the closed position. The fluid-driven actuator may utilize pressurized gas stored in a cylinder or reservoir within the anastomosis tool. A separate clip applier may be used to close the entry hole made by the anvil in a target vessel.

Abstract: A method of performing anastomosis between a graft vessel and a target vessel, each having a circumferential wall and a lumen therethrough, may include providing an anastomosis tool including a tissue effector and a fluid-driven actuator operationally connected to that tissue effector; connecting the fluid-driven actuator to an energy source; placing an end of the graft vessel in proximity to the side of the target vessel; and actuating the fluid-driven actuator to connect the end of the graft vessel to the side of the target vessel.

Abstract: A method for closing a patent foramen ovale in the heart tissue of a patient may include percutaneously advancing a connector applicator to the patent foramen ovale, registering the connector applicator with the patent foramen ovale, deploying connectors into heart tissue to close the patent foramen ovale; and percutaneously removing the connector applicator from the heart. One or more anchors may be used to register the connector applicator with the patent foramen ovale. The connector applicator may include a driver having a longitudinal passage therein, where at least part of at least one connector is positioned within said passage.

Abstract: An anastomosis tool may include a connector holder connected to an anvil. The connector holder may be bifurcated and configured to straddle the graft vessel. The connector holder may be generally U-shaped. The connector holder may be shaped to extend around more than half of the circumference of the graft vessel.

Abstract: A system for performing anastomosis between a graft vessel and a target vessel includes a tissue effector that may be configured to deploy a user-selectable number of connectors. The system includes an anvil that enters the wall of the target vessel through an entry hole that is spaced apart from the anastomosis site, and at least one anvil entry hole sealer may be utilized to substantially seal the anvil entry hole upon withdrawal of the anvil. The system may include a shield and a cutter, both of which are movable relative to the anvil, where the shield is configured to protect the graft vessel from the cutter. The cutter may include an incising element movable from a stowed position to an active position.

Abstract: An anastomosis staple has a base from which multiple deformable tines extend. At least one tine may be offset from at least one other tine. The tines are moveable from a first configuration to a second configuration. The staple optionally includes at least one alignment guide.