Abstract: Biocompatible macroporous microcarriers, including microcarrier beads, microspheres, capsules, microsponges, hydrogels and other matrix forms, appropriate for use in a shaking flask or bioreactor to culture cells are described herein that can be used to create an edible structure for consumption or research investigation. Biocompatible, macroporous microcarriers can be dissolved or remain in the final product. Biocompatible macroporous microcarriers are formed by saccharides that are cross-linked via chemical induction with agitated cryo-gelation. Cross-linked macroporous, saccharide-microcarriers are coupled to adherence factors that enable cell binding. Finally, the cells are attached to the microcarrier for proliferation.

Abstract: The invention is directed to a device for obtaining accurate registration of handwritten impressions on continuous business form sets which are detachable into individual form sets by means of longitudinally spaced transverse perforations. The device includes a pocket for receiving the continuous business form sets folded in a zig-zag manner and has a registration plate defining a writing surface for the individual business form set upon which a handwritten entry is made. The outer edge of the registration plate coacts with the transverse perforation to ensure accurate registration of the original sheet and copy sheets of an individual business form set upon which a handwritten entry is made.