Patents by Inventor Philippa Jane Webster
Philippa Jane Webster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10077466Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: GrantFiled: March 28, 2016Date of Patent: September 18, 2018Assignee: NanoString Technologies, Inc.Inventors: Philippa Jane Webster, Timothy Dahl
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Publication number: 20180135099Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods of making and using such probes are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: ApplicationFiled: January 2, 2018Publication date: May 17, 2018Inventors: Gary K. GEISS, Sean M. FERREE, Philippa Jane WEBSTER, Krassen M. DIMITROV
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Publication number: 20180066309Abstract: The invention provides compositions and methods for the detection of gene copy number and/or chromosome copy number in a multiplexed reaction. The assays and kits described herein are applicable for the identification, diagnosing, and monitoring of disorders including, but not limited to cancer, developmental and degenerative disease, neurological disorders, and stem cell disorders.Type: ApplicationFiled: October 10, 2017Publication date: March 8, 2018Inventors: Paul Nevin Hengen, Gary K. Geiss, Nathan Elliott, Philippa Jane Webster
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Patent number: 9890419Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods of making and using such probes are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: GrantFiled: May 20, 2016Date of Patent: February 13, 2018Assignees: NanoString Technologies, Inc., The Institute for Systems BiologyInventors: Gary K. Geiss, Sean M. Ferree, Philippa Jane Webster, Krassen M. Dimitrov
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Patent number: 9856519Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: GrantFiled: March 28, 2016Date of Patent: January 2, 2018Assignee: NanoString Technologies, Inc.Inventors: Philippa Jane Webster, Timothy Dahl
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Patent number: 9758834Abstract: The application describes methods for diagnosing subjects with leukemia by detecting fusion genes associated with the onset of leukemia.Type: GrantFiled: March 28, 2012Date of Patent: September 12, 2017Assignee: NanoString Technologies, Inc.Inventors: Philippa Jane Webster, Richard Kemble Boykin, Jeannette Nussbaum
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Publication number: 20160273026Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: ApplicationFiled: March 28, 2016Publication date: September 22, 2016Inventors: Philippa Jane WEBSTER, Timothy DAHL
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Publication number: 20160265025Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods of making and using such probes are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: ApplicationFiled: May 20, 2016Publication date: September 15, 2016Inventors: Gary K. GEISS, Sean M. FERREE, Philippa Jane WEBSTER, Krassen M. DIMITROV
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Publication number: 20160201120Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: ApplicationFiled: March 28, 2016Publication date: July 14, 2016Inventors: Philippa Jane WEBSTER, Timothy DAHL
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Patent number: 9376712Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: GrantFiled: August 1, 2013Date of Patent: June 28, 2016Assignee: NanoString Technologies, Inc.Inventors: Philippa Jane Webster, Timothy Dahl
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Patent number: 9371563Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods of making and using such probes are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: GrantFiled: March 11, 2013Date of Patent: June 21, 2016Assignees: NanoString Technologies, Inc., The Institute for Systems BiologyInventors: Gary K. Geiss, Sean M. Ferree, Philippa Jane Webster, Krassen M. Dimitrov
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Publication number: 20140017688Abstract: The application describes methods for diagnosing subjects with leukemia by detecting fusion genes associated with the onset of leukemia.Type: ApplicationFiled: March 28, 2012Publication date: January 16, 2014Applicant: NANOSTRING TECHNOLOGIES, INC.Inventors: Philippa Jane Webster, Richard Kemble Boykin, Jeannette Nussbaum
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Publication number: 20140005067Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: ApplicationFiled: August 1, 2013Publication date: January 2, 2014Inventors: Philippa Jane Webster, Timothy Dahl
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Publication number: 20130230851Abstract: The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to coded, labeled probes that are capable of binding to and identifying target molecules based on the probes' label codes. Methods of making and using such probes are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.Type: ApplicationFiled: March 11, 2013Publication date: September 5, 2013Applicants: THE INSTITUTE FOR SYSTEMS BIOLOGY, NANOSTRING TECHNOLOGIES, INC.Inventors: Gary K. Geiss, Sean M. Ferree, Philippa Jane Webster, Krassen M. Dimitrov