Patents by Inventor Philippe Alexandre Guy

Philippe Alexandre Guy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 9-oxo-ODE as a biomarker for healthy aging
    Patent number: 9817003
    Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort including centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose a method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using 9-oxo-ODE as biomarker.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: November 14, 2017
    Assignee: NESTEC S.A.
    Inventors: Sebastiano Collino, Ivan Montoliu Roura, Francois-Pierre Martin, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • 4-oxo-2-pentenoic acid and skin pigmentation
    Patent number: 9693942
    Abstract: The present invention relates generally to the field of enhancing skin appearance. One aspect of the invention aims to provide a composition comprising 4-oxo-2-pentenoic acid for use in the reduction or prevention of regions of the skin with darker pigmentation. The present invention also relates to cosmetic use of a composition comprising 4-oxo-2-pentenoic acid for the reduction or prevention of regions of the skin with darker pigmentation.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: July 4, 2017
    Assignee: Nestec S.A.
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Francis Foata, Marjorie Guitard, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi
  • 4-oxo-2-pentenoic acid and liver disorders
    Patent number: 9486425
    Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to treatment or prevention of liver disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders. A further subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders linked to an insufficient activity of phase II enzymes in the liver.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: November 8, 2016
    Assignee: Nestec S.A.
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi
  • PC-O 40:1 as a biomarker for healthy aging
    Patent number: 9341615
    Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort including centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose a method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using PC-O 40:1 as biomarker.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: May 17, 2016
    Assignee: NESTEC S.A.
    Inventors: Sebastiano Collino, Ivan Montoliu Roura, Francois-Pierre Martin, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • P-cresol sulphate as a biomarker for healthy aging
    Patent number: 9322821
    Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort including centenarians, elderly and young adults. The invention provides biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose an in vitro method of diagnosing a lifestyle that allows to delay and/or avoid ageing related chronic inflammatory disorders using p-cresol sulphate as biomarker.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: April 26, 2016
    Assignee: NESTEC S.A.
    Inventors: Sebastiano Collino, Ivan Montoliu Roura, Francois-Pierre Martin, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • PC-O 44:4—a biomarker for visceral adiposity
    Patent number: 9261520
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 44:4 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: February 16, 2016
    Assignee: NESTEC S.A.
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • 4-oxo-2-pentenoic acid and brain health
    Patent number: 9259404
    Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of brain health, for example brain protection, maintenance of cognitive function, prevention of cognitive decline and prevention of cognitive disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cognitive decline.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: February 16, 2016
    Assignee: Nestec S.A.
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Jane Durga, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi, Pierre Magistretti, Evelyne Ruchti, Sylvain Lengacher, Igor Allaman
  • PC-O 42:4—a biomarker for visceral adiposity
    Patent number: 9261521
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 42:4 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: February 16, 2016
    Assignee: NETSEC S.A.
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • 4-oxo-2-pentenoic acid and cardiovascular health
    Patent number: 9238015
    Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of cardiovascular disorders, for example, atherosclerosis, high blood pressure, coronary heart disease, myocardial infarction, angina pectoris, stroke, and heart failure. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cardiovascular disorders.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: January 19, 2016
    Assignee: Nestec S.A.
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi
  • PC-O 44:6—a biomarker for visceral adiposity
    Patent number: 9201081
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 44:6 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: December 1, 2015
    Assignee: NESTEC S.A.
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • Phenylacetylglutamine as a biomarker for healthy aging
    Patent number: 9201064
    Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort including centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose an in vitro method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using phenylacetylglutamine (PAG) as biomarker.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: December 1, 2015
    Assignee: NESTEC S.A.
    Inventors: Sebastiano Collino, Ivan Montoliu Roura, Francois-Pierre Martin, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • PC-O 44:4 - A BIOMARKER FOR VISCERAL ADIPOSITY
    Publication number: 20150147817
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 44:4 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Application
    Filed: November 25, 2014
    Publication date: May 28, 2015
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • 4-OXO-2-PENTENOIC ACID AND BRAIN HEALTH
    Publication number: 20150105464
    Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of brain health, for example brain protection, maintenance of cognitive function, prevention of cognitive decline and prevention of cognitive disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cognitive decline.
    Type: Application
    Filed: March 25, 2013
    Publication date: April 16, 2015
    Applicant: NESTEC S.A.
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Jane Durga, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi, Pierre Magistretti, Evelyne Ruchti, Sylvain Lengacher, Igor Allaman
  • HYDROXY-SPHINGOMYELIN 22:1 AS A BIOMARKER FOR HEALTHY AGING
    Publication number: 20150105296
    Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort compromising centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose a method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using hydroxy-sphingomyelin SM-OH-22:1 as biomarker.
    Type: Application
    Filed: September 19, 2014
    Publication date: April 16, 2015
    Inventors: Sebastiano Collino, Ivan Montoliu Roura, Francois-Pierre Martin, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • PC-O 42:4 - A BIOMARKER FOR VISCERAL ADIPOSITY
    Publication number: 20150096357
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 42:4 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Application
    Filed: December 12, 2014
    Publication date: April 9, 2015
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • 4-OXO-2-PENTENOIC ACID AND CARDIOVASCULAR HEALTH
    Publication number: 20150087707
    Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of cardiovascular disorders, for example, atherosclerosis, high blood pressure, coronary heart disease, myocardial infarction, angina pectoris, stroke, and heart failure. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cardiovascular disorders.
    Type: Application
    Filed: March 25, 2013
    Publication date: March 26, 2015
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi
  • 4-OXO-2-PENTENOIC ACID AND LIVER DISORDERS
    Publication number: 20150087706
    Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to treatment or prevention of liver disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders. A further subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders linked to an insufficient activity of phase II enzymes in the liver.
    Type: Application
    Filed: March 25, 2013
    Publication date: March 26, 2015
    Inventors: Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi
  • PC-O 44:6 - A BIOMARKER FOR VISCERAL ADIPOSITY
    Publication number: 20150080264
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 44:6 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 19, 2015
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • PC-O 44:4 - A BIOMARKER FOR VISCERAL ADIPOSITY
    Publication number: 20150075262
    Abstract: The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 44:4 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 19, 2015
    Inventors: Francois-Pierre Martin, Ivan Montoliu Roura, Philippe Alexandre Guy, Serge Andre Dominique Rezzi
  • PC-O 40:1 AS A BIOMARKER FOR HEALTHY AGING
    Publication number: 20150072320
    Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort compromising centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose a method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using PC—O 40:1 as biomarker.
    Type: Application
    Filed: September 19, 2014
    Publication date: March 12, 2015
    Inventors: Sebastiano Collino, Ivan Montoliu Roura, Francois-Pierre Martin, Philippe Alexandre Guy, Serge Andre Dominique Rezzi