Abstract: A system of additive-manufacturing by laser melting of a powder bed. The system includes a first laser unit selectively emitting a first laser beam to form at least one layer of material by melting the powder bed; a second laser unit selectively emitting a second laser beam to machine at least a portion of the layer of material; and an optical unit enabling to focus the first laser beam on the powder bed to be melted and the second laser beam on the layer of material to be machined. The system is able to produce a part by successive stacking of melted then machined layers of material. A process of additive-manufacturing by laser melting of a powder bed is also contemplated.

Abstract: The present invention relates to an antibody specific for the protofibrillar form of the A? peptide for use in the prevention and/or the treatment of a neurodegenerative disease involving A? peptide aggregation, in particular for the prevention of Alzheimer's disease and/or the treatment of an early stage of symptomatic Alzheimer's disease. The antibody may thus be used before the appearance of memory loss and impaired cognitive functions or at the earliest stages of the disease. Said antibody has indeed a neuronal cell protective effect against A? peptide-induced neurotoxicity.

Abstract: A system of additive-manufacturing by laser melting of a powder bed. The system includes a first laser unit selectively emitting a first laser beam to form at least one layer of material by melting the powder bed; a second laser unit selectively emitting a second laser beam to machine at least a portion of the layer of material; and an optical unit enabling to focus the first laser beam on the powder bed to be melted and the second laser beam on the layer of material to be machined. The system is able to produce a part by successive stacking of melted then machined layers of material. A process of additive-manufacturing by laser melting of a powder bed is also contemplated.

Abstract: An assembly for a drug delivery device (1) comprises a housing (5), a rotation member (15), a drive member (16) and at least one correction member (7). The rotation member (15) is adapted to be rotated with respect to the housing (5) in a first rotational direction for delivering a dose of a drug (11). The drive member (16) is coupleable to the rotation member (15) for delivering the dose. In a delivery mode, the drive member (16) and the rotation member (15) are coupled such that the drive member (16) follows rotational movement of the rotation member (15) in the first rotational direction due to mechanical interaction of the rotation member (15) and the drive member (16). In a correction mode, the rotation member (15) and the drive member (16) are decoupled such that the rotation member (15) is rotatable in the first rotational direction with respect to the drive member (16).

Abstract: An assembly for a drug delivery device comprises a housing, a rotation member, a drive member and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.

Abstract: An assembly for a drug delivery device (1) comprises a housing (5), a rotation member (15), a drive member (16) and at least one correction member (7). The rotation member (15) is adapted to be rotated with respect to the housing (5) in a first rotational direction for delivering a dose of a drug (11). The drive member (16) is coupleable to the rotation member (15) for delivering the dose. In a delivery mode, the drive member (16) and the rotation member (15) are coupled such that the drive member (16) follows rotational movement of the rotation member (15) in the first rotational direction due to mechanical interaction of the rotation member (15) and the drive member (16). In a correction mode, the rotation member (15) and the drive member (16) are decoupled such that the rotation member (15) is rotatable in the first rotational direction with respect to the drive member (16).

Abstract: The invention relates to a gelatin substitution product, characterized in that it contains essentially a vegetable fat, in particular in that it contains essentially cocoa butter. Application to the production of culinary confectionery preparations.

Abstract: Novel polymer nanovectors or particles and use thereof as medication and/or diagnostic agents.

Abstract: The present relates to a method and system for determining the position and orientation of implants located in a body part of a patient. The method and system comprise determining voxels having an intensity value corresponding to implants in a three-dimensional radiographic representation of the body part. The method and system further comprise generating multiple random virtual implants, providing a score for each virtual implant, until obtaining a score that identifies implants. The score is based on a number of voxels having an intensity value corresponding to implants contained in each generated virtual implant. And the method and system comprise determining, based on the score of virtual implants, the position and orientation of the implants located in the body part.

Abstract: A method for quality control of a weld bead made using a welding tool. The method collects, by an optical pyrometer having a high frequency acquisition sensor, at least one signal representative of the temperature of a melted portion of the weld bead, and includes a frequency phase for checking that the recurring frequencies are within an acceptable range of reference frequencies, to determine if the weld bead is defective.

Abstract: A method for quality control of a weld bead made using a welding tool. The method collects, by an optical pyrometer having a high frequency acquisition sensor, at least one signal representative of the temperature of a melted portion of the weld bead, and includes a frequency phase for checking that the recurring frequencies are within an acceptable range of reference frequencies, to determine if the weld bead is defective.

Abstract: The present invention relates to the use of cocoa butter as a replacement for dairy butter and oils in culinary preparations, in particular in the following applications: cooking, seasoning, preparation of emulsions and of doughs (tart dough, fritter dough and the like), preservation of foods, etc.

Abstract: A process for tempering chocolate comprising adding cryogenic cocoa butter to melted chocolate and mixing until the cryogenic cocoa butter is melted.

Abstract: The invention relates to a gelatin substitution product, characterized in that it contains essentially a vegetable fat, in particular in that it contains essentially cocoa butter. Application to the production of culinary confectionery preparations.

Abstract: The instant invention relates to the use of an alpha-2-delta ligand in the treatment of chronic obstructive pulmonary disease (COPD) and diseases associated with a diagnosis of COPD, and particularly to the treatment of chronic cough, which may be unrelated to COPD.

Abstract: The invention relates to a connection device having a switch which is particularly, but not exclusively, suited or use in making a connection between a portable appliance having an antenna, such as a radiotelephone, and a connection device, such as a device mounted in a motor vehicle and connected to the antenna of the motor vehicle.

Abstract: The electric retarder comprises a stator (1) mounted through a frame (11) to a casing (4) of a vehicle drive axle and a rotor with two disks (2) supported by a central plate (17), which plate is mounted on a collar (8) fitted on the end of a stub-shaft (3) extending from the casing and is coupled to a universal joint. For assembling the plate to the collar and the end flange (24) of the universal joint to the plate, and to close the jaw (23) of this universal joint formed by two bearing blocks (26) and two clamps (27), on the corresponding journals, recourse is had to twelve screws, namely four screws A, four screws B and four screws C staggered angularly by about 30.degree. with respect to each other about the axis X of the retarder.

Abstract: The energization of the electric speed reducer of a vehicle, whose friction brakes for the front wheels and rear wheels are respectively controlled by two independent pressurized fluid circuits, is controlled by a plurality of pressure contacts. These pressure contacts are actuated by the pressure of a fluid and this pressure is permanently given a value tied to the higher of the two pressures existing in the two independent pressurized fluid circuits. A dual control relay valve of the ++ type is connected to these two circuits and to an independent source of pressurized fluid.