Abstract: A method of lubricating a surface of a tubular element for a medicament delivery device includes the steps of moving a device relative to the tubular element for a medicament delivery device, contacting the tubular element with a brush portion of the device, and depositing lubricant agent on the surface of the tubular element to lubricate a surface of the tubular element.

Abstract: A device for lubricating a surface of a tubular element includes a shaft portion having a longitudinal axis, and a brush portion located on the shaft portion. The brush portion comprises at least one radial projection having a helical form. The protrusion comprises at least one contact zone for contacting a surface. An outer diameter of the helical form formed by the at least one contact zone is tapered at both longitudinal ends of the brush portion such that the outer diameter of the helical form is reduced at the longitudinal ends of the brush portion. The brush portion is formed from a brush portion material and a lubricant agent which is transferred from the at least one contact zone to a surface during use.

Abstract: A device for lubricating a surface of a tubular element includes a shaft portion having a longitudinal axis, where the shaft portion is formed from plastic, and a brush portion located on the shaft portion. The brush portion has at least one contact zone for contacting a surface. The brush portion is formed from a brush portion material and a lubricant agent, which is transferred from the at least one contact zone to a surface during use.

Abstract: An apparatus for lubricating a surface of a tubular element for a medicament delivery device includes a rotatable drum comprising a tubular element receiving section configured to receive a tubular element to be lubricated. The drum is rotatable about its central axis. The apparatus comprises a device manipulator comprising a device handler at one end of a rod. The device handler is configured to receive a shaft portion of a device, and the rod moves a device through a received tubular element. The device manipulator is rotatable about the central axis of the rotatable drum.

Abstract: A spring carrier for receiving, retaining, and discharging of a coil spring in a manufacturing process includes an elongate hollow body defining an inner cavity to receive the coil spring and an opening at a first proximal end of the hollow body for the insertion of the coil spring into the inner cavity and extraction of the coil spring from the inner cavity. The hollow body includes a second distal end opposite to the first proximal end. The hollow body includes a magnetic member to magnetically attract and retain the coil spring when the coil spring is located within the inner cavity.

Abstract: A spring carrier for receiving, retaining, and discharging of a coil spring in a manufacturing assembly process includes an elongate hollow body defining an inner cavity to receive the coil spring and an opening at a first proximal end of the hollow body for the insertion of the coil spring into the inner cavity and extraction of the coil spring from the inner cavity. A deflectable member is located proximate to the first proximal end and includes a retaining portion that retains the coil spring when the coil spring is located within the inner cavity. The deflectable member is movable between a first unbiased position, where the retaining portion extends into the inner cavity to retain the coil spring within the inner cavity, and a second biased position, where the retaining portion is disposed outwardly to allow the coil spring to be extracted from the inner cavity through the opening.

Abstract: A spring carrier for receiving, retaining and discharging of a coil spring in a manufacturing assembly process comprising an elongate hollow body defining an inner cavity configured to receive a coil spring and an opening at a first proximal end of the hollow body for the insertion and/or extraction of a coil spring into/from the inner cavity. The hollow body includes a second distal end opposite to the first proximal end. At least one deflectable member is located proximate to the second distal end of the hollow body and includes a retaining formation which is configured to engage a coil spring when located within the inner cavity. The deflectable member is movable between a first unbiased position, whereby the retaining formation extends into the inner cavity to engage the coil spring when located within the inner cavity, and a second biased position, whereby the retaining formation is disposed outwardly to disengage a coil spring when located within the inner cavity.

Abstract: A needle safety device includes a sleeve having proximal and distal portions separated by a radially-inwardly projecting ledge. A ring in the proximal portion is movable between a first position spaced from the ledge, and a second position adjacent to or abutting the ledge. A shield with at least one radially deformable tab receives the syringe and is movable in the sleeve between an initial position with the tab adjacent to or abutting the ledge, an injection position with the tab spaced from the ledge, and a protection position with the tab located distally from the ledge. The tab, during movement between initial and injection positions, deforms inwardly and traverses the inner surface of the ring, and during movement between injection and protection positions, translates with the ring from the first to the second position, and subsequently deforms inwardly and traverses the inner surface of the ring and the ledge.

Abstract: A needle safety device includes a sleeve having proximal and distal portions separated by a radially-inwardly projecting ledge. A ring in the proximal portion is movable between a first position spaced from the ledge, and a second position adjacent to or abutting the ledge. A shield with at least one radially deformable tab receives the syringe and is movable in the sleeve between an initial position with the tab adjacent to or abutting the ledge, an injection position with the tab spaced from the ledge, and a protection position with the tab located distally from the ledge. The tab, during movement between initial and injection positions, deforms inwardly and traverses the inner surface of the ring, and during movement between injection and protection positions, translates with the ring from the first to the second position, and subsequently deforms inwardly and traverses the inner surface of the ring and the ledge.

Abstract: A preventive and therapeutic drug for a neurodegenerative disease containing, as an active ingredient, a cyclohexenone long-chain alcohol compound represented by formula (1) wherein each of R1, R2, and R3 represents a hydrogen atom or a methyl group; and X represents a C10–C28 alkylene group or alkenylene group. Since the compound of the present invention exhibits excellent neurite-extension ability and an inhibition effect on disorders caused by mutation in an SOD gene, it is useful as the active ingredient of a preventive and therapeutic drug for neurodegenerative diseases, inter alia, amyotrophic lateral sclerosis, and as the active ingredient of an inhibitory drug for disorders caused by mutation in an SOD gene.