Patents by Inventor Philippe Collas

Philippe Collas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic ungulates capable of human antibody production
    Patent number: 7803981
    Abstract: The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of xenogenous antibodies (e.g., non-bovine antibodies), preferably human antibodies.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: September 28, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: James M. Robl, Philippe Collas, Eddie Sullivan, Poothappillai Kasinathan, Richard A. Goldsby, Yoshimi Kuroiwa, Kazuma Tomizuka, Isao Ishida, Barbara Osborne
  • Methods for altering cell fate
    Patent number: 7736895
    Abstract: The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type. These reprogrammed cells may be used in a variety of medical applications for treating a mammal in need of a particular cell type.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: June 15, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Philippe Collas, James M. Robl
  • Methods for altering cell fate to generate T-cells specific for an antigen of interest
    Patent number: 7491534
    Abstract: The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type (e.g., T-cells). These reprogrammed cells may be used in a variety of medical applications for treating a mammal in need of a particular cell type.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: February 17, 2009
    Assignee: Kirin Holdings Kabushiki Kaisha
    Inventors: Philippe Collas, James M. Robl, Bjorn Steen Skalhegg
  • Transgenic ungulates capable of human antibody production
    Publication number: 20080040821
    Abstract: The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of xenogenous antibodies (e.g., non-bovine antibodies), preferably human antibodies.
    Type: Application
    Filed: June 20, 2007
    Publication date: February 14, 2008
    Inventors: James Robl, Philippe Collas, Eddie Sullivan, Poothappillai Kasinathan, Richard Goldsby, Yoshimi Kuroiwa, Kazuma Tomizuka, Isao Ishida, Barbara Osborne
  • Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
    Patent number: 7253334
    Abstract: The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: August 7, 2007
    Assignee: Aurox, LLC
    Inventors: Philippe Collas, James M. Robl, Eddie Sullivan, Poothappillai Kasinathan
  • Methods for cloning mammals using reprogrammed donor chromatin or donor cells
    Publication number: 20060212952
    Abstract: The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells.
    Type: Application
    Filed: May 24, 2006
    Publication date: September 21, 2006
    Inventors: Philippe Collas, James Robl, Eddie Sullivan, P. Kasinathan
  • Methods for altering cell fate
    Publication number: 20050014258
    Abstract: The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type. These reprogrammed cells may be used in a variety of medical applications for treating a mammal in need of a particular cell type.
    Type: Application
    Filed: August 2, 2004
    Publication date: January 20, 2005
    Inventors: Philippe Collas, James Robl
  • Methods for altering cell fate to generate T-cells specific for an antigen of interest
    Publication number: 20040072288
    Abstract: The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type (e.g., T-cells). These reprogrammed cells may be used in a variety of medical applications for treating a mammal in need of a particular cell type.
    Type: Application
    Filed: April 30, 2003
    Publication date: April 15, 2004
    Inventors: Philippe Collas, James M. Robl, Bjorn Steen Skalhegg
  • Transgenic ungulates capable of human antibody production
    Publication number: 20040068760
    Abstract: The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of xenogenous antibodies (e.g., non-bovine antibodies), preferably human antibodies.
    Type: Application
    Filed: May 19, 2003
    Publication date: April 8, 2004
    Inventors: James M. Robl, Philippe Collas, Eddie Sullivan, P. Kasinathan, Richard A. Goldsby, Yoshimi Kuroiwa, Kazuma Tomizuka, Isao Ishida
  • Methods for cloning mammals using reprogrammed donor chromatin or donor cells
    Publication number: 20030046722
    Abstract: The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells.
    Type: Application
    Filed: December 21, 2001
    Publication date: March 6, 2003
    Inventors: Philippe Collas, James M. Robl, Eddie Sullivan, P. Kasinathan
  • Methods for altering cell fate
    Publication number: 20020142397
    Abstract: The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type. These reprogrammed cells may be used in a variety of medical applications for treating a mammal in need of a particular cell type.
    Type: Application
    Filed: December 10, 2001
    Publication date: October 3, 2002
    Inventors: Philippe Collas, James M. Robl