Patents by Inventor Philippe Cronet

Philippe Cronet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CYCLODEXTRINS TO IMPROVE THE SPECIFICITY, SENSITIVITY AND YIELD OF NUCLEIC ACID AMPLIFICATION REACTIONS
    Publication number: 20110256592
    Abstract: The invention is directed to methods for in vitro DNA synthesis catalysed by a DNA polymerase using cyclodextrins. The invention also relates to methods, compositions and kits comprising cyclodextrins for the amplification of a nucleic acid. The use of cyclodextrins improves the specificity, sensibility and/or yield of the amplification reaction. The invention is related more particularly to kits, compositions and methods for carrying out PCR reactions comprising a cyclodextrin.
    Type: Application
    Filed: December 14, 2009
    Publication date: October 20, 2011
    Applicant: EUROGENTEC S.A
    Inventors: Marie-Claire Beckers, Philippe Cronet, Adeline Vitale, Eric Collette, Arzu Gullukaya
  • Carboxypertidase U (Cpu) Mutants
    Publication number: 20080175834
    Abstract: This invention relates to mutant forms of carboxypeptidase U with increased thermal stability relative to wild-type. In addition to the individual thermal stabilizing mutations identified (at positions 166, 204, 219, 230, 251, 315), the inventors have identified a region (S327-H357) that is crucial to the stability of CPU. The invention relates to nucleic acid encoding such mutant forms and the polypeptides encoded thereby. The invention also relates to methods and materials for making CPU mutants with increased thermal stability relative to wild-type and their use, for example to produce crystals of CPU or proCPU for 3-dimensional structure determination, or in therapy.
    Type: Application
    Filed: November 10, 2004
    Publication date: July 24, 2008
    Applicant: AstraZenca AB
    Inventors: Philippe Cronet, Wolfgang Knecht, Cecilia Ann-Christin Malmborg Hager, Mats Andersson, Christina Furebring