Patents by Inventor Philippe de Taxis du Poet

Philippe de Taxis du Poet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-thrombin polypeptides
    Patent number: 5439820
    Abstract: The present invention relates to anti-thrombin polypeptides isolated from the leech Hirudinaria manillensis and to processes for their preparation. The polypeptides of the invention may be modified by way of amino acid extension at either or each end, and may be subjected to post-translational modification. The anti-thrombin polypeptides may be prepared by isolating them from the tissue or secretions of the leech Hirudinaria manillensis but they also may be synthetized by recombinant DNA methods. According to this latter aspect, the invention provides DNA sequences, expression vectors and host cell lines for the recombinant preparation of the polypeptides. The anti-thrombin polypeptides of the invention find an useful application in the treatment of venous thrombosis, vascular shunt occlusion and thrombin-induced disseminated intravascular coagulation.
    Type: Grant
    Filed: June 23, 1994
    Date of Patent: August 8, 1995
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Paolo Sarmientos, Philippe De Taxis du Poet, Giampaolo Nitti, Emanuela Scacheri
  • Anti-thrombin polypeptides and pharmaceutical compositions thereof
    Patent number: 5356875
    Abstract: The present invention relates to anti-thrombin polypeptides isolated from the leech Hirudinaria manillensis and to processes for their preparation.The polypeptides of the invention may be modified by way of amino acid extension at either or each end, and may be subjected to post-translational modification.The anti-thrombin polypeptides may be prepared by isolating them from the tissue or secretions of the leech Hirudinaria manillensis but they also may be synthetized by recombinant DNA methods.According to this latter aspect, the invention provides DNA sequences, expression vectors and host cell lines for the recombinant preparation of the polypeptides.The anti-thrombin polypeptides of the invention find an useful application in the treatment of venous thrombosis, vascular shunt occlusion and thrombin-induced disseminated intravascular coagulation.
    Type: Grant
    Filed: February 26, 1992
    Date of Patent: October 18, 1994
    Assignee: Farmitalia Carlo ERBA S.r.l.
    Inventors: Paolo Sarmientos, Philippe de Taxis du Poet, Giampaolo Nitti, Emanuela Scacheri