Patents by Inventor Philippe Delagrange

Philippe Delagrange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted cyclic compounds
    Patent number: 7115752
    Abstract: The invention concerns compounds of formula (I): R—A—R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 3, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renaud, Philippe Delagrange
  • Phenylnaphthalene compounds
    Publication number: 20060106111
    Abstract: The invention relates to compounds of formula (I): wherein: A represents R3 represents alkoxy, R4 is as defined in the description, p is 1, 2 or 3, and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Application
    Filed: November 4, 2003
    Publication date: May 18, 2006
    Inventors: Sophie Poissonnier-Durieux, Said Yous, Daniel Lesieur, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Substituted cyclic compounds
    Publication number: 20050124682
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Application
    Filed: September 23, 2004
    Publication date: June 9, 2005
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
    Patent number: 6872851
    Abstract: The invention concerns compounds of formula (I): R—A—R? wherein: A is as defined in the description; R represent, a group (V), wherein R?a and R?a are as defined in the description, or R forms with A a cyclic structure as defined in the description; R? represents a (CH2)t—R2 group wherein q, t, and R2 are as defined in the description. The invention is useful for preparing medicines.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: March 29, 2005
    Assignee: Les Laboratories Servier
    Inventors: Daniel Lesieur, Frédérique Klupsch, Gérald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Substituted cyclic compounds
    Publication number: 20050059729
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Application
    Filed: September 23, 2004
    Publication date: March 17, 2005
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Indenoindolone compounds
    Patent number: 6844445
    Abstract: Compound of formula (I): wherein: R represents hydrogen or a group selected from alkenyl and optionally substituted alkyl, each of R1 to R8, which may be identical or different, represents hydrogen or a group selected from alkyl, alkenyl, hydroxy, alkoxy, alkenyloxy, arylalkyl, arylalkoxy, carboxy, acyloxy and arylcarbonyloxy, or one of R1 to R8 forms with an adjacent one R1 to R8 an alkylenedioxy group, its optical isomers when they exist, and addition salts thereof with a pharmaceutically acceptable acid or base, with the proviso that: when R does not represent hydrogen, then at least one of R1 to R8 represents hydroxy or acyloxy, and the compounds of formula (I) are other than indeno[1,2-b]indol-10(5H)-one and medicinal products containing the same which are useful for treatment of disorders of the melatoninergic system.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: January 18, 2005
    Assignee: Les Laboratoires Servier
    Inventors: Michel Wierzbicki, Marie-Françoise Boussard, Anne Rousseau, Jean Albert Boutin, Philippe Delagrange
  • New isoquinoline compounds
    Publication number: 20040204449
    Abstract: The invention relatests compound of formula (I): 1
    Type: Application
    Filed: April 8, 2004
    Publication date: October 14, 2004
    Inventors: Sophie Poissonnier-Durieux, Valerie Wallez, Anne Gasnereau, Said Yous, Daniel Lesieur, Philippe Delagrange, Pierre Renard, Caroline Bennejean, Jean Albert Boutin, Valerie Audinot
  • Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
    Publication number: 20040002490
    Abstract: The invention concerns compounds of formula (I): R-A-R′ wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description, and medicaments containing the same.
    Type: Application
    Filed: June 16, 2003
    Publication date: January 1, 2004
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
    Publication number: 20040002491
    Abstract: The invention concerns compounds of formula (1): R-A-R′ wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description, and medicaments containing the same.
    Type: Application
    Filed: June 16, 2003
    Publication date: January 1, 2004
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Polycyclic azaindole compounds
    Patent number: 6667304
    Abstract: The invention relates to compound of formula (I): wherein: G1 represents an alkylene chain as defined in the description, A represents R2 and R3 represent hydrogen, alkyl, alkoxy or hydroxy or together form oxo, R4 and R5 represent hydrogen, R1 is as defined in the description, and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: December 23, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Hervé Van De Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard
  • Substituted dimeric compounds
    Patent number: 6635650
    Abstract: The invention relates to compounds of formula (I): A-G1-Cy-G2-Cy-G3-B  (I) wherein: A represents NR1C(Q)R2, C(Q)NR2R3 or NR1C(Q)NR2R3, B represents NR1C(Q)R2, C(Q)NR2R3, NR1C(Q)NR2R3, C(Q)OR1, NR1C(Q)OR2 or NR2R3, G1 and G3 represent an optionally substituted alkylene chain, Cy represents a ring structure G2 represents a chain and medicinal products containing the same which are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: October 21, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Said Yous, Carole Descamps-Francois, François Lefoulon, Gérald Guillaumet, Marie-Claude Viaud, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds
    Patent number: 6620809
    Abstract: The invention relates to compound of formula (I): wherein: G represents an alkylene chain containing from 1 to 4 carbon atoms, A represents X represents oxygen or sulphur and R2 and R1 are as defined in the description and medicinal products containing the same which are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: September 16, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Marie-Claude Viaud, Gérald Guillaumet, Philippe Daubos, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
    Patent number: 6605632
    Abstract: The invention concerns compounds of formula (I): R—A—R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: August 12, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frédérique Klupsch, Gérald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • New polycyclic azaindole compounds
    Publication number: 20030134847
    Abstract: The invention relates to compound of formula (I): 1
    Type: Application
    Filed: October 9, 2002
    Publication date: July 17, 2003
    Inventors: Gerald Guillaumet, Marie-Claude Viaud, Herve Van De Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard
  • Cyclic compounds having a cycloalkylene chain
    Patent number: 6583319
    Abstract: The invention relates to compounds of for a (I): wherein: R represents ORa, SRa or Ra or a cyclic group A is a cyclic structure G1 and G2 represent an alkylene chain or a single bond B represents —NR1aC(Q)R2a, —NR1aC(Q)NR2aR3a or C(Q)NR1aR2a p and q are such that 1≦p+q≦4, and medicinal products containing the same which are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: June 24, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Michel Langlois, Monique Mathe-Allainmat, Marie Lefas-Le Gall, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • New polycyclic azaindole compounds
    Publication number: 20030105087
    Abstract: The invention relates to compound of formula (I): 1
    Type: Application
    Filed: October 9, 2002
    Publication date: June 5, 2003
    Inventors: Gerald Guillaumet, Marie-Claude Viaud, Herve Van De Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard
  • Polycyclic azaindole compounds
    Patent number: 6495543
    Abstract: The invention relates to compounds of formula (I): wherein: G1 represents an alkylene chain as defined in the description, A represents R2 and R3 represent hydrogen, alkyl, alkoxy or hydroxy or together form oxo, R4 and R5 represent hydrogen or together form aryl, R1 is as defined in the description. and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: December 17, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Hervé Van De Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard
  • Indenoindolone compounds
    Publication number: 20020173531
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: March 19, 2002
    Publication date: November 21, 2002
    Inventors: Michel Wierzbicki, Marie-Francoise Boussard, Anne Rousseau, Jean Albert Boutin, Philippe Delagrange
  • Isoindoloindolone compounds
    Patent number: 6465660
    Abstract: Compound of formula (I): wherein: R1, R2, R3, R4, R5, R6 and R8, which may be identical or different, each represents hydrogen, alkyl, arylalkyl, hydroxy, alkoxy, arylalkoxy, acyloxy, arylcarbonyloxy, carboxyalkyl or carboxy, R7 represents hydrogen, hydroxy, alkoxy, arylalkoxy, acyloxy or arylcarbonyloxy group, or one of R1 to R8, together with another of R1 to R8 adjacent to it, forms an alkylenedioxy, its optical isomers, and addition salts thereof with a pharmaceutically acceptable acid or base.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: October 15, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Michel Wierzbicki, Marie-Françoise Boussard, Anne Rousseau, Jean Albert Boutin, Philippe Delagrange
  • Tricyclic compounds, preparation method and pharmaceutical compositions containing same
    Patent number: 6423870
    Abstract: The invention concerns compounds of formula (I) in which: A forms a tricyclic system of formula A1, A2, A3 or A4; R1 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or oxo group; (R2)m and (R3)m′ are such as defined in the description; n represents an integer such that 0≦n≦3; p represents an integer such as defined in the description; B represents a group (a) or (b). The invention is useful for preparing medicines.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: July 23, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Michel Langlois, Monique Mathe-Allainmat, Carole Jellimann, Jean Andrieux, Caroline Bennejean, Pierre Renard, Philippe Delagrange